Keyword search (4,164 papers available)

"Cossette MP" Authored Publications:

Title Authors PubMed ID
1 Does phasic dopamine release cause policy updates? Carter F; Cossette MP; Trujillo-Pisanty I; Pallikaras V; Breton YA; Conover K; Caplan J; Solis P; Voisard J; Yaksich A; Shizgal P; 38039083
PSYCHOLOGY
2 Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation. Hernandez G, Cossette MP, Shizgal P, Rompré PP 27616984
PSYCHOLOGY
3 17β-estradiol locally increases phasic dopamine release in the dorsal striatum. Shams WM, Cossette MP, Shizgal P, Brake WG 29175028
CSBN
4 Early Adolescence is a Critical Period for the Maturation of Inhibitory Behavior. Reynolds LM, Yetnikoff L, Pokinko M, Wodzinski M, Epelbaum JG, Lambert LC, Cossette MP, Arvanitogiannis A, Flores C 30295713
PSYCHOLOGY
5 The neural substrates for the rewarding and dopamine-releasing effects of medial forebrain bundle stimulation have partially discrepant frequency responses. Cossette MP, Conover K, Shizgal P 26477378
CSBN
6 High Oestradiol Replacement Reverses Response Memory Bias in Ovariectomised Female Rats Regardless of Dopamine Levels in the Dorsal Striatum. Hussain D, Cossette MP, Brake WG 26929121
PSYCHOLOGY

 

Title:Early Adolescence is a Critical Period for the Maturation of Inhibitory Behavior.
Authors:Reynolds LMYetnikoff LPokinko MWodzinski MEpelbaum JGLambert LCCossette MPArvanitogiannis AFlores C
Link:https://www.ncbi.nlm.nih.gov/pubmed/30295713?dopt=Abstract
Publication:
Keywords:
PMID:30295713 Category:Cereb Cortex Date Added:2019-06-03
Dept Affiliation: PSYCHOLOGY
1 Integrated Program in Neuroscience, McGill University, Montréal, QC, Canada.
2 Department of Psychiatry and Department of Neurology and Neurosurgery, McGill University, Douglas Mental Health University Institute, Montréal, QC, Canada.
3 Department of Psychology, College of Staten Island, City University of New York, Staten Island, NY, USA.
4 CUNY Neuroscience Collaborative, The Graduate Center, City University of New York, New York, NY, USA.
5 Department of Psychology, Center for Studies in Behavioural Neurobiology, Concordia University, Montréal, QC, Canada.

Description:

Early Adolescence is a Critical Period for the Maturation of Inhibitory Behavior.

Cereb Cortex. 2018 Oct 06;:

Authors: Reynolds LM, Yetnikoff L, Pokinko M, Wodzinski M, Epelbaum JG, Lambert LC, Cossette MP, Arvanitogiannis A, Flores C

Abstract

Psychiatric conditions marked by impairments in cognitive control often emerge during adolescence, when the prefrontal cortex (PFC) and its inputs undergo structural and functional maturation and are vulnerable to disruption by external events. It is not known, however, whether there exists a specific temporal window within the broad range of adolescence when the development of PFC circuitry and its related behaviors are sensitive to disruption. Here we show, in male mice, that repeated exposure to amphetamine during early adolescence leads to impaired behavioral inhibition, aberrant PFC dopamine connectivity, and reduced PFC dopamine function in adulthood. Remarkably, these deficits are not observed following exposure to the exact same amphetamine regimen at later times. These findings demonstrate that there is a critical period for the disruption of the adolescent maturation of cognitive control and PFC dopamine function and suggest that early adolescence is particularly relevant to the emergence of psychopathology in humans.

PMID: 30295713 [PubMed - as supplied by publisher]





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