Keyword search (4,163 papers available)

"Darwish A" Authored Publications:

Title Authors PubMed ID
1 Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L; 40325266
ENCS
2 An Anatomically Shaped Mitral Valve for Hemodynamic Testing Darwish A; Papolla C; Rieu R; Kadem L; 38228812
ENCS
3 Spectral-Clustering of Lagrangian Trajectory Graphs: Application to Abdominal Aortic Aneurysms Darwish A; Norouzi S; Kadem L; 34845627
ENCS
4 Energy loss associated with in-vitro modeling of mitral annular calcification. Wiener PC, Darwish A, Friend E, Kadem L, Pressman GS 33591991
ENCS
5 Proper Orthogonal Decomposition Analysis of the Flow Downstream of a Dysfunctional Bileaflet Mechanical Aortic Valve. Darwish A, Di Labbio G, Saleh W, Kadem L 33469847
ENCS
6 Impact of Mitral Regurgitation on the Flow in a Model of a Left Ventricle. Papolla C, Darwish A, Kadem L, Rieu R 33000444
ENCS
7 Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve. Darwish A, Di Labbio G, Saleh W, Smadi O, Kadem L 31066923
ENCS

 

Title:Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve.
Authors:Darwish A,  Di Labbio G,  Saleh W,  Smadi O,  Kadem L
Link:https://www.ncbi.nlm.nih.gov/pubmed/31066923?dopt=Abstract
Publication:
Keywords:
PMID:31066923 Category:Artif Organs Date Added:2019-06-04
Dept Affiliation: ENCS
1 Laboratory of Cardiovascular Fluid Dynamics, Mechanical, Industrial and Aerospace Engineering, Concordia University, Montreal, Quebec, Canada.
2 Department of Biomedical Engineering, Hashemite University, Zarqa, Jordan.

Description:

Experimental investigation of the flow downstream of a dysfunctional bileaflet mechanical aortic valve.

Artif Organs. 2019 May 08;:

Authors: Darwish A, Di Labbio G, Saleh W, Smadi O, Kadem L

Abstract

Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart valves. This leads to risks of valve leaflet dysfunctions, a life-threatening event. In this experimental study, we investigate, using time-resolved planar particle image velocimetry, the flow characteristics in the ascending aorta in the presence of a dysfunctional bileaflet mechanical heart valve. Several configurations of leaflet dysfunctions are investigated and the induced flow disturbances in terms of velocity fields, viscous energy dissipation, wall shear stress and accumulation of viscous shear stresses are evaluated. We also explore the ability of a new set of parameters, solely based on the analysis of the normalized axial velocity profiles in the ascending aorta, to detect bileaflet mechanical heart valve dysfunctions and differentiate between the different configurations tested in this study. Our results show that a bileaflet mechanical heart valve dysfunction leads to a complex spectrum of flow disturbances with each flow characteristic evaluated having its own worst case scenario in terms of dysfunction configuration. We also show that the suggested approach based on the analysis of the normalized axial velocity profiles in the ascending aorta has the potential to clearly discriminate not only between normal and dysfunctional bilealfet heart valves but also between the different leaflet dysfunction configurations. This approach could be easily implemented using phase-contrast MRI to follow up patients with bileaflet mechanical heart valves. This article is protected by copyright. All rights reserved.

PMID: 31066923 [PubMed - as supplied by publisher]




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