Keyword search (4,164 papers available)

"Das S" Authored Publications:

Title Authors PubMed ID
1 Basic Science and Pathogenesis Borrie MJ; Phillips NA; Best S; Anastasiou-Ventura P; Aydogan T; Beaudoin C; Beuk J; Celotto I; Cole L; Das S; Fogarty J; Fouquet C; Gnassi L; Henri-Bellemare C; Pilon R; Sands J; Stirbu A; Truemner J; Chan S; Tucker A; Gajraj J; Bhangu J; Chertkow H; 41435411
CONCORDIA
2 Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA) Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W; 39636028
HKAP
3 Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses Steindorff AS; Aguilar-Pontes MV; Robinson AJ; Andreopoulos B; LaButti K; Kuo A; Mondo S; Riley R; Otillar R; Haridas S; Lipzen A; Grimwood J; Schmutz J; Clum A; Reid ID; Moisan MC; Butler G; Nguyen TTM; Dewar K; Conant G; Drula E; Henrissat B; Hansel C; Singer S; Hutchinson MI; de Vries RP; Natvig DO; Powell AJ; Tsang A; Grigoriev IV; 39266695
CSFG
4 A chloromethyl-triazole fluorescent chemosensor for O6-methylguanine DNA methyltransferase Ayan S; Rotaru AM; Kaye EG; Juneau G; Das S; Wilds CJ; Beharry AA; 38502038
CHEMBIOCHEM
5 Data and Tools Integration in the Canadian Open Neuroscience Platform Poline JB; Das S; Glatard T; Madjar C; Dickie EW; Lecours X; Beaudry T; Beck N; Behan B; Brown ST; Bujold D; Beauvais M; Caron B; Czech C; Dharsee M; Dugré M; Evans K; Gee T; Ippoliti G; Kiar G; Knoppers BM; Kuehn T; Le D; Lo D; Mazaheri M; MacFarlane D; Muja N; O' Brien EA; O' Callaghan L; Paiva S; Park P; Quesnel D; Rabelais H; Rioux P; Legault M; Tremblay-Mercier J; Rotenberg D; Stone J; Strauss T; Zaytseva K; Zhou J; Duchesne S; Khan AR; Hill S; Evans AC; 37024500
ENCS
6 A Simulation Toolkit for Testing the Sensitivity and Accuracy of Corticometry Pipelines OmidYeganeh M; Khalili-Mahani N; Bermudez P; Ross A; Lepage C; Vincent RD; Jeon S; Lewis LB; Das S; Zijdenbos AP; Rioux P; Adalat R; Van Eede MC; Evans AC; 34381348
PERFORM
7 The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ 31309917
PSYCHOLOGY
8 Cyberinfrastructure for Open Science at the Montreal Neurological Institute. Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C, Durcan TM, Campbell T, Moreau J, Dagher A, Collins DL, Karamchandani J, Bar-Or A, Fon EA, Hoge R, Baillet S, Rouleau G, Evans AC 28111547
IMAGING
9 Best practices in data analysis and sharing in neuroimaging using MRI. Nichols TE, Das S, Eickhoff SB, Evans AC, Glatard T, Hanke M, Kriegeskorte N, Milham MP, Poldrack RA, Poline JB, Proal E, Thirion B, Van Essen DC, White T, Yeo BT 28230846
IMAGING
10 Flavanone glycosides inhibit β-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Aβ aggregation in the amyloidogenic pathway. Ali MY, Jannat S, Edraki N, Das S, Chang WK, Kim HC, Park SK, Chang MS 31194956
BIOLOGY
11 Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri. Vesth TC, Nybo JL, Theobald S, Frisvad JC, Larsen TO, Nielsen KF, Hoof JB, Brandl J, Salamov A, Riley R, Gladden JM, Phatale P, Nielsen MT, Lyhne EK, Kogle ME, Strasser K, McDonnell E, Barry K, Clum A, Chen C, LaButti K, Haridas S, Nolan M, Sandor L, Kuo A, Lipzen A, Hainaut M, Drula E, Tsang A, Magnuson JK, Henrissat B, Wiebenga A, Simmons BA, Mäkelä MR, de Vries RP, Grigoriev IV, Mortensen UH, Baker SE, Andersen MR 30349117
CSFG
12 Boutiques: a flexible framework to integrate command-line applications in computing platforms. Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, Rousseau MÉ, Evans AC 29718199
ENCS

 

Title:Basic Science and Pathogenesis
Authors:Borrie MJPhillips NABest SAnastasiou-Ventura PAydogan TBeaudoin CBeuk JCelotto ICole LDas SFogarty JFouquet CGnassi LHenri-Bellemare CPilon RSands JStirbu ATruemner JChan STucker AGajraj JBhangu JChertkow H
Link:https://pubmed.ncbi.nlm.nih.gov/41435411/
DOI:10.1002/alz70855_100224
Publication:Alzheimer s & dementia : the journal of the Alzheimer s Association
Keywords:
PMID:41435411 Category: Date Added:2025-12-23
Dept Affiliation: CONCORDIA
1 Division of Geriatric Medicine, Western University, London, ON, Canada.
2 Lawson Research Institute, London, ON, Canada.
3 St. Joseph's Health Care London, London, ON, Canada.
4 Parkwood Institute, London, ON, Canada.
5 Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
6 Concordia University, Montréal, QC, Canada.
7 Lady Davis Research Institute, Montréal, QC, Canada.
8 Lady Davis Institute, Montréal, QC, Canada.
9 McGill Centre for Integrative Neuroscience, Montréal, QC, Canada.
10 Baycrest Health Sciences, Toronto, ON, Canada.
11 Institut universitaire de gériatrie de Montréal, Montréal, QC, Canada.
12 Lady Davis Resesarch Institute, Montréal, QC, Canada.
13 Lady Davis Research Insitute, Montréal, QC, Canada.
14 University of Toronto, Toronto, ON, Canada.
15 Western University, London, ON, Canada.
16 Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, QC, Canada.
17 Kimel Family Centre for Brain Health and Wellness and Anne & Allan Bank Centre for Clinical Research Trials, Baycrest Health Sciences, Toronto, ON, Canada.
18 Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
19 Baycrest and Rotman Research Institute, Toronto, ON, Canada.
20 McGill University, Montreal, QC, Canada.

Description:

Background: The Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND) used wide inclusion criteria recruiting participants across the spectrum from normal cognition to cognitive impairment to all types of clinical dementia, including mixed dementia. 1173 participants comprising 11 diagnostic cohorts, completed screening, clinical, neuropsychology, sensory and motor assessments, magnetic resonance imaging (MRI) and provided biomarker bio-samples.

Method: Recruitment was from advertising and specialty clinics for neurocognitive disorders and/or memory impairment. Robust data monitoring and cleaning occurred on the baseline and Time 2 data. Genetic, MRI, Cerebrospinal Fluid (CSF) and the majority of blood biomarkers analyses have been completed.

Result: Data releases uploaded to the Longitudinal Online Research and Imaging System (LORIS) include alpha numeric baseline data, neuroimaging analyses, CSF, genetic and blood biomarkers. 40 autopsies have been completed. 119 data access requests have been submitted to the Data Access Subcommittee. All returning participants will repeat Time 3 extensive clinical and neuropsychology assessments, MRI and provide bio-samples. Phase III new recruitment will include 400 diverse participants, with up to Grade 12 education, who are not cognitively impaired, or who have cognitive impairment, but not dementia. The balance of each cohort for sex/gender will be a consideration.

Conclusion: COMPASS-ND fills a knowledge gap by recruiting participants representing the full spectrum of neurodegeneration. This distinguishes COMPASS-ND from other large-scale studies. Challenges and strategies for engagement and research site level funding will be discussed. Data are available to registered researchers and trainees in Canada and around the world through data access requests.





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