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PubMed Publications| Keyword search (4,164 papers available) |  |
"Dimri V" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Intra-individual variability in cognitive performance predicts falls in older adults with chronic stroke | Dimri V; Davis JC; Boa Sorte Silva NC; Balbim GM; Eng JJ; Liu-Ambrose T; | 41474479 HKAP |
| Title: | Intra-individual variability in cognitive performance predicts falls in older adults with chronic stroke | ||||
| Authors: | Dimri V, Davis JC, Boa Sorte Silva NC, Balbim GM, Eng JJ, Liu-Ambrose T | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41474479/ | ||||
| DOI: | 10.1007/s40520-025-03287-y | ||||
| Publication: | Aging clinical and experimental research | ||||
| Keywords: | Chronic stroke; Cognition; Falls; Intra-individual variability; Reaction time; | ||||
| PMID: | 41474479 | Category: | Date Added: | 2025-12-31 | |
| Dept Affiliation: |
HKAP
1 Aging, Mobility, and Cognitive Health Laboratory, University of British Columbia, Vancouver, BC, Canada. 2 Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada. 3 Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. 4 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. 5 Faculty of Management, University of British Columbia Okanagan, Kelowna, BC, Canada. 6 Department of Kinesiology, Health, and Applied Physiology, Concordia University, Montreal, QC, Canada. 7 Aging, Mobility, and Cognitive Health Laboratory, University of British Columbia, Vancouver, BC, Canada. teresa.ambrose@ubc.ca. 8 Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada. teresa.ambrose@ubc.ca. 9 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada. teresa.ambrose@ubc.ca. 10 Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. teresa.ambrose@ubc.ca. 11 Djavad Mowafaghian Centre for Brain Health, c/o Liu-Ambrose Lab, 2215 Wesbrook Mall, Vancouver, BC, V6T 2B5, Canada. teresa.ambrose@ubc.ca. |
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Description: |
Background: Common consequences of a stroke include impaired motor and cognitive function, with both being linked to increased falls and frailty. Intra-individual variability (IIV) of cognitive performance, which refers to the within-person trial-to-trial variation in reaction time during cognitive tasks, may be a useful predictor for falls in older adults with chronic stroke. Objective: To examine whether IIV or "traditional" reaction time (RT) measures of cognitive performance predict falls in older adults with chronic stroke. Methods: This study is a secondary analysis of a proof-of-concept randomized controlled trial (RCT) among community-dwelling adults with a history of stroke, aged 55 years and older, able to walk 6 m, and without dementia. Residualised intraindividual standard deviation (rISD) was the measure of IIV and mean RT was the "traditional" measure of performance on a computerised Stroop Task. Falls were tracked and adjudicated over six months. Results: 120 participants with a mean (SD) age of 70 (8) years, and 46 (38%) female participants, experienced a mean of 0.61 (SD = 1.15) falls over 6 months. rISD for the congruent Stroop Task condition predicted falls, such that a one-unit increase was associated with 20.5% increase in fall rate. Conclusion: The findings suggest that IIV metrics may have the potential in fall risk screening post-stroke. Further research is required to evaluate whether IIV in cognitive performance can be improved via interventions such as cognitive training and physical activity. |
