Keyword search (4,163 papers available)

"Dumeaux V" Authored Publications:

Title Authors PubMed ID
1 Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to anti-fungal compounds Dumeaux V; Massahi S; Bettauer V; Mottola A; Dukovny A; Khurdia SS; Costa ACBP; Omran RP; Simpson S; Xie JL; Whiteway M; Berman J; Hallett MT; 37888959
BIOLOGY
2 A metagenomic-based study of two sites from the Barbadian reef system Simpson S; Bettauer V; Ramachandran A; Kraemer S; Mahon S; Medina M; Vallès Y; Dumeaux V; Vallès H; Walsh D; Hallett MT; 37009568
BIOLOGY
3 A Deep Learning Approach to Capture the Essence of Candida albicans Morphologies Bettauer V; Costa ACBP; Omran RP; Massahi S; Kirbizakis E; Simpson S; Dumeaux V; Law C; Whiteway M; Hallett MT; 35972285
BIOLOGY
4 The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans Omran RP; Ramírez-Zavala B; Aji Tebung W; Yao S; Feng J; Law C; Dumeaux V; Morschhäuser J; Whiteway M; 34849863
PERFORM
5 ChIP-seq protocol for sperm cells and embryos to assess environmental impacts and epigenetic inheritance Lismer A; Lambrot R; Lafleur C; Dumeaux V; Kimmins S; 34159325
PERFORM
6 Signal-mediated localization of Candida albicans pheromone response pathway components Costa ACBP; Omran RP; Law C; Dumeaux V; Whiteway M; 33793759
PERFORM
7 Histone H3 lysine 4 trimethylation in sperm is transmitted to the embryo and associated with diet-induced phenotypes in the offspring. Lismer A, Dumeaux V, Lafleur C, Lambrot R, Brind'Amour J, Lorincz MC, Kimmins S 33596408
PERFORM
8 Sperm histone H3 lysine 4 trimethylation is altered in a genetic mouse model of transgenerational epigenetic inheritance Lismer A; Siklenka K; Lafleur C; Dumeaux V; Kimmins S; 33068438
PERFORM
9 Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits. Tamming RJ, Dumeaux V, Jiang Y, Shafiq S, Langlois L, Ellegood J, Qiu LR, Lerch JP, Bérubé NG 32610139
PERFORM
10 Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts. Jaju Bhattad G, Jeyarajah MJ, McGill MG, Dumeaux V, Okae H, Arima T, Lajoie P, Bérubé NG, Renaud SJ 32366868
PERFORM
11 The time-varying effect of radiotherapy after breast-conserving surgery for DCIS. Rakovitch E, Sutradhar R, Hallett M, Thompson AM, Gu S, Dumeaux V, Whelan TJ, Paszat L 31368035
PERFORM
12 Screening of Candida albicans GRACE library revealed a unique pattern of biofilm formation under repression of the essential gene ILS1. Costa ACBP, Omran RP, Correia-Mesquita TO, Dumeaux V, Whiteway M 31235750
PERFORM
13 Interactions between the tumor and the blood systemic response of breast cancer patients. Dumeaux V, Fjukstad B, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Børresen-Dale AL, Bongo LA, Lund E, Hallett M 28957325
BIOLOGY
14 Mms21: A Putative SUMO E3 Ligase in Candida albicans That Negatively Regulates Invasiveness and Filamentation, and Is Required for the Genotoxic and Cellular Stress Response. Islam A, Tebbji F, Mallick J, Regan H, Dumeaux V, Omran RP, Whiteway M 30530734
PERFORM
15 Role of SUMOylation in differential ERα transcriptional repression by tamoxifen and fulvestrant in breast cancer cells. Traboulsi T, El Ezzy M, Dumeaux V, Audemard E, Mader S 30190545
PERFORM

 

Title:Interactions between the tumor and the blood systemic response of breast cancer patients.
Authors:Dumeaux VFjukstad BFjosne HEFrantzen JOHolmen MMRodegerdts ESchlichting EBørresen-Dale ALBongo LALund EHallett M
Link:https://www.ncbi.nlm.nih.gov/pubmed/28957325?dopt=Abstract
DOI:10.1371/journal.pcbi.1005680
Publication:PLoS computational biology
Keywords:
PMID:28957325 Category:PLoS Comput Biol Date Added:2019-06-07
Dept Affiliation: BIOLOGY
1 Department of Biology, Concordia University, Montreal, QC, Canada.
2 School of Computer Science, McGill University, Montreal, QC, Canada.
3 Department of Computer Science, UiT the Arctic University of Norway, Tromsø, Norway.
4 Department of Surgery, St. Olavs University Hospital, Trondheim, Norway.
5 Faculty of Medicine, The Norwegian University of Technology and Science, Trondheim, Norway.
6 University Hospital of North-Norway, Narvik, Norway.
7 Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
8 Nordland Central Hospital, Bodø, Norway.
9 Department of Cancer, Oslo University Hospital, Oslo, Norway.
10 Department of Cancer Genetics, Oslo University Hospital, Oslo, Norway.
11 Institute of Community Medicine, UiT the Arctic University of Norway, Tromsø, Norway.

Description:

Interactions between the tumor and the blood systemic response of breast cancer patients.

PLoS Comput Biol. 2017 Sep;13(9):e1005680

Authors: Dumeaux V, Fjukstad B, Fjosne HE, Frantzen JO, Holmen MM, Rodegerdts E, Schlichting E, Børresen-Dale AL, Bongo LA, Lund E, Hallett M

Abstract

Although systemic immunity is critical to the process of tumor rejection, cancer research has largely focused on immune cells in the tumor microenvironment. To understand molecular changes in the patient systemic response (SR) to the presence of BC, we profiled RNA in blood and matched tumor from 173 patients. We designed a system (MIxT, Matched Interactions Across Tissues) to systematically explore and link molecular processes expressed in each tissue. MIxT confirmed that processes active in the patient SR are especially relevant to BC immunogenicity. The nature of interactions across tissues (i.e. which biological processes are associated and their patterns of expression) varies highly with tumor subtype. For example, aspects of the immune SR are underexpressed proportionally to the level of expression of defined molecular processes specific to basal tumors. The catalog of subtype-specific interactions across tissues from BC patients provides promising new ways to tackle or monitor the disease by exploiting the patient SR.

PMID: 28957325 [PubMed - indexed for MEDLINE]





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