PERFORM Publications

Keyword search (4,164 papers available)

Title		Authors	PubMed ID
1	The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond	Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterbe	41020412 SOH
2	The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond	Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterberg H; S	40778177 PSYCHOLOGY
3	Individualized prediction of future cognition based on developmental changes in cortical anatomy	Khundrakpam B; Booij L; Jeon S; Karama S; Tohka J; Evans AC;	40567557 PSYCHOLOGY
4	Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA)	Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; Bélanger N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello C; Cynader M; Dang-Vu T; Das S; Dixon RA; Ducharme S; Einstein G; Evans AC; Fahnestock M; Feldman H; Ferland G; Finger E; Fisk JD; Fogarty J; Fon E; Gan-Or Z; Gauthier S; Greenwood C; Henri-Bellemare C; Herrmann N; Hogan DB; Hsiung R; Itzhak I; Jacklin K; Lanctôt K; Lim A; MacKenzie I; Masellis M; Maxwell C; McAiney C; McGilton K; McLaurin J; Mihailidis A; Mohades Z; Montero-Odasso M; Morgan D; Naglie G; Nygaard H; O' Connell M; Petersen R; Pilon R; Rajah MN; Rapoport M; Roach P; Robillard JM; Rogaeva E; Rosa-Neto P; Rylett J; Sadavoy J; St George-Hyslop P; Seitz D; Smith E; Stefanovic B; Vedel I; Walker JD; Wellington C; Whitehead V; Wittich W;	39636028 HKAP
5	Web-based processing of physiological noise in fMRI: addition of the PhysIO toolbox to CBRAIN	Valevicius D; Beck N; Kasper L; Boroday S; Bayer J; Rioux P; Caron B; Adalat R; Evans AC; Khalili-Mahani N;	37841811 ENCS
6	Data and Tools Integration in the Canadian Open Neuroscience Platform	Poline JB; Das S; Glatard T; Madjar C; Dickie EW; Lecours X; Beaudry T; Beck N; Behan B; Brown ST; Bujold D; Beauvais M; Caron B; Czech C; Dharsee M; Dugré M; Evans K; Gee T; Ippoliti G; Kiar G; Knoppers BM; Kuehn T; Le D; Lo D; Mazaheri M; MacFarlane D; Muja N; O' Brien EA; O' Callaghan L; Paiva S; Park P; Quesnel D; Rabelais H; Rioux P; Legault M; Tremblay-Mercier J; Rotenberg D; Stone J; Strauss T; Zaytseva K; Zhou J; Duchesne S; Khan AR; Hill S; Evans AC;	37024500 ENCS
7	Numerical uncertainty in analytical pipelines lead to impactful variability in brain networks	Kiar G; Chatelain Y; de Oliveira Castro P; Petit E; Rokem A; Varoquaux G; Misic B; Evans AC; Glatard T;	34724000 ENCS
8	The BigBrainWarp toolbox for integration of BigBrain 3D histology with multimodal neuroimaging	Paquola C; Royer J; Lewis LB; Lepage C; Glatard T; Wagstyl K; DeKraker J; Toussaint PJ; Valk SL; Collins DL; Khan A; Amunts K; Evans AC; Dickscheid T; Bernhardt BC;	34431476 IMAGING
9	A Simulation Toolkit for Testing the Sensitivity and Accuracy of Corticometry Pipelines	OmidYeganeh M; Khalili-Mahani N; Bermudez P; Ross A; Lepage C; Vincent RD; Jeon S; Lewis LB; Das S; Zijdenbos AP; Rioux P; Adalat R; Van Eede MC; Evans AC;	34381348 PERFORM
10	File-based localization of numerical perturbations in data analysis pipelines.	Salari A, Kiar G, Lewis L, Evans AC, Glatard T	33269388 ENCS
11	Comparing perturbation models for evaluating stability of neuroimaging pipelines.	Kiar G, de Oliveira Castro P, Rioux P, Petit E, Brown ST, Evans AC, Glatard T	32831546 IMAGING
12	Cyberinfrastructure for Open Science at the Montreal Neurological Institute.	Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C, Durcan TM, Campbell T, Moreau J, Dagher A, Collins DL, Karamchandani J, Bar-Or A, Fon EA, Hoge R, Baillet S, Rouleau G, Evans AC	28111547 IMAGING
13	Best practices in data analysis and sharing in neuroimaging using MRI.	Nichols TE, Das S, Eickhoff SB, Evans AC, Glatard T, Hanke M, Kriegeskorte N, Milham MP, Poldrack RA, Poline JB, Proal E, Thirion B, Van Essen DC, White T, Yeo BT	28230846 IMAGING
14	Boutiques: a flexible framework to integrate command-line applications in computing platforms.	Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, Rousseau MÉ, Evans AC	29718199 ENCS
15	A Serverless Tool for Platform Agnostic Computational Experiment Management.	Kiar G, Brown ST, Glatard T, Evans AC	30890927 ENCS
16	Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: A review of state-of-the-Art, challenges, and opportunities for studying brain chemistry.	Khalili-Mahani N, Rombouts SA, van Osch MJ, Duff EP, Carbonell F, Nickerson LD, Becerra L, Dahan A, Evans AC, Soucy JP, Wise R, Zijdenbos AP, van Gerven JM	28145075 PERFORM

Title:	Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: A review of state-of-the-Art, challenges, and opportunities for studying brain chemistry.
Authors:	Khalili-Mahani N, Rombouts SA, van Osch MJ, Duff EP, Carbonell F, Nickerson LD, Becerra L, Dahan A, Evans AC, Soucy JP, Wise R, Zijdenbos AP, van Gerven JM
Link:	https://www.ncbi.nlm.nih.gov/pubmed/28145075?dopt=Abstract
DOI:	10.1002/hbm.23516
Publication:	Human brain mapping
Keywords:	PK/PD modeling; arterial spin labeling; biomarkers; brain chemistry; drug; functional connectivity; pharma-fMRI; pharmacological neuroimaging; resting state fMRI; translational research;
PMID:	28145075	Category:	Hum Brain Mapp	Date Added:	2019-04-15
Dept Affiliation:	PERFORM 1 McGill Centre for Integrative Neuroscience, Montreal Neurological Institute, McGill University, Montreal, Canada. 2 PERFORM Centre, Concordia University, Montreal, Canada. 3 Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands. 4 Institute of Psychology and Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands. 5 Oxford Centre for Functional MRI of the Brain, Oxford University, Oxford, United Kingdom. 6 Biospective Inc, Montreal, Quebec, Canada. 7 McLean Hospital, Belmont, Massachusetts. 8 Harvard Medical School, Boston, Massachusetts. 9 Center for Pain and the Brain, Harvard Medical School & Boston Children's Hospital, Boston, Massachusetts. 10 Department of Anesthesiology, Leiden University Medical Centre, Leiden, The Netherlands. 11 McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Canada. 12 Cardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff, United Kingdom. 13 Centre for Human Drug Research, Leiden University Medical Centre, Leiden, The Netherlands.

Description:

Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: A review of state-of-the-Art, challenges, and opportunities for studying brain chemistry.

Hum Brain Mapp. 2017 04;38(4):2276-2325

Authors: Khalili-Mahani N, Rombouts SA, van Osch MJ, Duff EP, Carbonell F, Nickerson LD, Becerra L, Dahan A, Evans AC, Soucy JP, Wise R, Zijdenbos AP, van Gerven JM

Abstract

A decade of research and development in resting-state functional MRI (RSfMRI) has opened new translational and clinical research frontiers. This review aims to bridge between technical and clinical researchers who seek reliable neuroimaging biomarkers for studying drug interactions with the brain. About 85 pharma-RSfMRI studies using BOLD signal (75% of all) or arterial spin labeling (ASL) were surveyed to investigate the acute effects of psychoactive drugs. Experimental designs and objectives include drug fingerprinting dose-response evaluation, biomarker validation and calibration, and translational studies. Common biomarkers in these studies include functional connectivity, graph metrics, cerebral blood flow and the amplitude and spectrum of BOLD fluctuations. Overall, RSfMRI-derived biomarkers seem to be sensitive to spatiotemporal dynamics of drug interactions with the brain. However, drugs cause both central and peripheral effects, thus exacerbate difficulties related to biological confounds, structured noise from motion and physiological confounds, as well as modeling and inference testing. Currently, these issues are not well explored, and heterogeneities in experimental design, data acquisition and preprocessing make comparative or meta-analysis of existing reports impossible. A unifying collaborative framework for data-sharing and data-mining is thus necessary for investigating the commonalities and differences in biomarker sensitivity and specificity, and establishing guidelines. Multimodal datasets including sham-placebo or active control sessions and repeated measurements of various psychometric, physiological, metabolic and neuroimaging phenotypes are essential for pharmacokinetic/pharmacodynamic modeling and interpretation of the findings. We provide a list of basic minimum and advanced options that can be considered in design and analyses of future pharma-RSfMRI studies. Hum Brain Mapp 38:2276-2325, 2017. © 2017 Wiley Periodicals, Inc.

PMID: 28145075 [PubMed - indexed for MEDLINE]

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