Keyword search (4,164 papers available)

"Gardner MPH" Authored Publications:

Title Authors PubMed ID
1 Different behavioral measures of conditioned magazine activity can tell different stories about brain function Volz S; Loewinger G; Marquez I; Fevola S; Kang M; Reverte I; Krishnan A; Gardner MPH; Iordanova MD; Esber GR; 41922165
CSBN
2 Disentangling prediction error and value in a formal test of dopamine s role in reinforcement learning Usypchuk AA; Maes EJP; Lozzi M; Avramidis DK; Schoenbaum G; Esber GR; Gardner MPH; Iordanova MD; 40738112
CSBN
3 Hippocampal output suppresses orbitofrontal cortex schema cell formation Zong W; Zhou J; Gardner MPH; Zhang Z; Costa KM; Schoenbaum G; 40229506
CONCORDIA
4 Integrating past experiences Leir TMW; Gardner MPH; 40146623
PSYCHOLOGY
5 Neuroscience: Setting the neurobiological occasions for hierarchical learning and inference Ratemi M; Gardner MPH; 39626624
PSYCHOLOGY
6 Calcium activity is a degraded estimate of spikes Hart EE; Gardner MPH; Panayi MC; Kahnt T; Schoenbaum G; 36368324
PSYCHOLOGY
7 Anterior cingulate neurons signal neutral cue pairings during sensory preconditioning Hart EE; Gardner MPH; Schoenbaum G; 34936884
PSYCHOLOGY
8 Causal evidence supporting the proposal that dopamine transients function as temporal difference prediction errors. Maes EJP, Sharpe MJ, Usypchuk AA, Lozzi M, Chang CY, Gardner MPH, Schoenbaum G, Iordanova MD 31959935
CSBN

 

Title:Causal evidence supporting the proposal that dopamine transients function as temporal difference prediction errors.
Authors:Maes EJPSharpe MJUsypchuk AALozzi MChang CYGardner MPHSchoenbaum GIordanova MD
Link:https://www.ncbi.nlm.nih.gov/pubmed/31959935?dopt=Abstract
DOI:10.1038/s41593-019-0574-1
Publication:Nature neuroscience
Keywords:
PMID:31959935 Category:Nat Neurosci Date Added:2020-01-22
Dept Affiliation: CSBN
1 Department of Psychology/Centre for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada.
2 Department of Psychology, University of California, Los Angeles, CA, USA.
3 Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, USA.
4 Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, USA. geoffrey.schoenbaum@nih.gov.
5 Departments of Anatomy & Neurobiology and Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA. geoffrey.schoenbaum@nih.gov.
6 Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University, Baltimore, MD, USA. geoffrey.schoenbaum@nih.gov.
7 Department of Psychology/Centre for Studies in Behavioural Neurobiology, Concordia University, Montreal, Quebec, Canada. mihaela.iordanova@concordia.ca.

Description:

Causal evidence supporting the proposal that dopamine transients function as temporal difference prediction errors.

Nat Neurosci. 2020 Jan 20;:

Authors: Maes EJP, Sharpe MJ, Usypchuk AA, Lozzi M, Chang CY, Gardner MPH, Schoenbaum G, Iordanova MD

Abstract

Reward-evoked dopamine transients are well established as prediction errors. However, the central tenet of temporal difference accounts-that similar transients evoked by reward-predictive cues also function as errors-remains untested. In the present communication we addressed this by showing that optogenetically shunting dopamine activity at the start of a reward-predicting cue prevents second-order conditioning without affecting blocking. These results indicate that cue-evoked transients function as temporal-difference prediction errors rather than reward predictions.

PMID: 31959935 [PubMed - as supplied by publisher]





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