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PubMed Publications| Keyword search (4,163 papers available) |  |
"Gauthier CJ" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Cardiorespiratory fitness in relation to cerebral vascular and metabolic health in older adults with coronary artery disease | Sanami S; Tremblay SA; Potvin-Jutras Z; Rezaei A; Sabra D; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41680492 SOH |
| 2 | Greater cardiorespiratory fitness is associated with higher cerebral blood flow and lower oxygen extraction fraction in healthy older adults | Sanami S; Rezaei A; Tremblay SA; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41543005 SOH |
| 3 | Biomarkers | Zhou J; Wearn A; Huck J; Hughes CS; Baracchini G; Sylvain E; Tremblay-Mercier J; Poirier J; Breitner JCSCS; Villeneuve S; Chakravarty MM; Tardif CL; Gauthier CJ; Daugherty AM; Turner GR; Spreng RN; | 41499788 ENCS |
| 4 | The Impact of Coronary Artery Disease on Brain Vascular and Metabolic Health: Links to Cognitive Function | Sanami S; Tremblay SA; Rezaei A; Potvin-Jutras Z; Sabra D; Intzandt B; Gagnon C; Mainville-Berthiaume A; Wright L; Gayda M; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 41452711 SOH |
| 5 | Alzheimer s Imaging Consortium | Intzandt B; Potvin-Jutras Z; Whittingstall K; Gauthier CJ; | 41433411 CONCORDIA |
| 6 | Public Health | Intzandt B; Potvin-Jutras Z; Whittingstall K; Gauthier CJ; | 41435069 CONCORDIA |
| 7 | Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition | Potvin-Jutras Z; Tremblay PL; Mohammadi H; Villeneuve S; Spreng RN; Gauthier CJ; | 41353310 SOH |
| 8 | The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond | Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterbe | 41020412 SOH |
| 9 | Multivariate white matter microstructure alterations in older adults with coronary artery disease | Tremblay SA; Potvin-Jutras Z; Sabra D; Rezaei A; Sanami S; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Leppert IR; Tardif CL; Steele CJ; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ; | 40829939 SOH |
| 10 | The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond | Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterberg H; S | 40778177 PSYCHOLOGY |
| 11 | Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan | Farahani A; Liu ZQ; Ceballos EG; Hansen JY; Wennberg K; Zeighami Y; Dadar M; Gauthier CJ; Dagher A; Misic B; | 40729400 PHYSICS |
| 12 | Assessing quantitative MRI techniques using multimodal comparisons | Carter F; Anwander A; Johnson M; Goucha T; Adamson H; Friederici AD; Lutti A; Gauthier CJ; Weiskopf N; Bazin PL; Steele CJ; | 40705745 SOH |
| 13 | Variations in perfusion detectable in advance of microstructure in white matter aging | Robinson TD; Sun YL; Chang PTH; Gauthier CJ; Chen JJ; | 40694306 PHYSICS |
| 14 | Longitudinal relationships among cerebrospinal fluid biomarkers, cerebral blood flow, and grey matter volume in individuals with a familial history of Alzheimer s disease | Sanami S; Intzandt B; Huck J; Villeneuve S; Iturria-Medina Y; Gauthier CJ; Prevent-Ad Research Group None; | 40347524 CONCORDIA |
| 15 | Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer s disease | Tremblay SA; Nathan Spreng R; Wearn A; Alasmar Z; Pirhadi A; Tardif CL; Chakravarty MM; Villeneuve S; Leppert IR; Carbonell F; Medina YI; Steele CJ; Gauthier CJ; | 40086421 PSYCHOLOGY |
| 16 | Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility | Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ; | 40079560 SOH |
| 17 | Alzheimer's Imaging Consortium | Tremblay SA; Spreng RN; Wearn A; Alasmar Z; Pirhadi A; Tardif CL; Chakravarty MM; Villeneuve S; Leppert IR; Carbonell F; Medina YI; Steele CJ; Gauthier CJ; | 39782998 CONCORDIA |
| 18 | Biomarkers | Tremblay SA; Spreng RN; Wearn A; Alasmar Z; Pirhadi A; Tardif CL; Chakravarty MM; Villeneuve S; Leppert IR; Carbonell F; Medina YI; Steele CJ; Gauthier CJ; | 39785351 CONCORDIA |
| 19 | Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility | Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ; | 39416007 SOH |
| 20 | Neuromodulatory subcortical nucleus integrity is associated with white matter microstructure, tauopathy and APOE status | Wearn A; Tremblay SA; Tardif CL; Leppert IR; Gauthier CJ; Baracchini G; Hughes C; Hewan P; Tremblay-Mercier J; Rosa-Neto P; Poirier J; Villeneuve S; Schmitz TW; Turner GR; Spreng RN; | 38830849 SOH |
| 21 | MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics | Tremblay SA; Alasmar Z; Pirhadi A; Carbonell F; Iturria-Medina Y; Gauthier CJ; Steele CJ; | 38463982 SOH |
| 22 | Iron Deposition and Distribution Across the Hippocampus Is Associated with Pattern Separation and Pattern Completion in Older Adults at Risk for Alzheimer's Disease | Zhou J; Wearn A; Huck J; Hughes C; Baracchini G; Tremblay-Mercier J; Poirier J; Villeneuve S; Tardif CL; Chakravarty MM; Daugherty AM; Gauthier CJ; Turner GR; Spreng RN; | 38388425 PSYCHOLOGY |
| 23 | Decreased long-range temporal correlations in the resting-state functional magnetic resonance imaging blood-oxygen-level-dependent signal reflect motor sequence learning up to 2 weeks following training | Jäger AP; Bailey A; Huntenburg JM; Tardif CL; Villringer A; Gauthier CJ; Nikulin V; Bazin PL; Steele CJ; | 38124341 SOH |
| 24 | Modeling venous bias in resting state functional MRI metrics | Huck J; Jäger AT; Schneider U; Grahl S; Fan AP; Tardif C; Villringer A; Bazin PL; Steele CJ; Gauthier CJ; | 37498014 PERFORM |
| 25 | Cerebral blood flow in schizophrenia: A systematic review and meta-analysis of MRI-based studies | Percie du Sert O; Unrau J; Gauthier CJ; Chakravarty M; Malla A; Lepage M; Raucher-Chéné D; | 36341843 CRDH |
| 26 | Motor sequences; separating the sequence from the motor. A longitudinal rsfMRI study | Jäger AP; Huntenburg JM; Tremblay SA; Schneider U; Grahl S; Huck J; Tardif CL; Villringer A; Gauthier CJ; Bazin PL; Steele CJ; | 34704176 PERFORM |
| 27 | Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults | Sabra D; Intzandt B; Desjardins-Crepeau L; Langeard A; Steele CJ; Frouin F; Hoge RD; Bherer L; Gauthier CJ; | 34582484 PERFORM |
| 28 | Comparing the effect of Cognitive vs. Exercise Training on brain MRI outcomes in healthy older adults: A systematic review | Intzandt B; Vrinceanu T; Huck J; Vincent T; Montero-Odasso M; Gauthier CJ; Bherer L; | 34245760 PERFORM |
| 29 | White matter microstructural changes in short-term learning of a continuous visuomotor sequence | Tremblay SA; Jäger AT; Huck J; Giacosa C; Beram S; Schneider U; Grahl S; Villringer A; Tardif CL; Bazin PL; Steele CJ; Gauthier CJ; | 33885965 PERFORM |
| 30 | A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer's Disease | Badji A; de la Colina AN; Boshkovski T; Sabra D; Karakuzu A; Robitaille-Grou MC; Gros C; Joubert S; Bherer L; Lamarre-Cliche M; Stikov N; Gauthier CJ; Cohen-Adad J; Girouard H; | 32741837 PERFORM |
| 31 | BOLD signal physiology: Models and applications. | Gauthier CJ, Fan AP | 29544818 IMAGING |
| 32 | High resolution atlas of the venous brain vasculature from 7 T quantitative susceptibility maps. | Huck J, Wanner Y, Fan AP, Jäger AT, Grahl S, Schneider U, Villringer A, Steele CJ, Tardif CL, Bazin PL, Gauthier CJ | 31278570 PSYCHOLOGY |
| 33 | Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults. | Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ | 31342831 PERFORM |
| 34 | Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity. | Tardif CL, Gauthier CJ, Steele CJ, Bazin PL, Schäfer A, Schaefer A, Turner R, Villringer A | 26318050 PERFORM |
| 35 | Elevated brain oxygen extraction fraction measured by MRI susceptibility relates to perfusion status in acute ischemic stroke. | Fan AP, Khalil AA, Fiebach JB, Zaharchuk G, Villringer A, Villringer K, Gauthier CJ | 30732551 PHYSICS |
| 36 | Arterial stiffness and brain integrity: A review of MRI findings. | Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ | 31063866 PERFORM |
| 37 | Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women. | Dupuy O, Gauthier CJ, Fraser SA, Desjardins-Crèpeau L, Desjardins M, Mekary S, Lesage F, Hoge RD, Pouliot P, Bherer L | 25741267 PERFORM |
| 38 | Investigation of the confounding effects of vasculature and metabolism on computational anatomy studies. | Tardif CL, Steele CJ, Lampe L, Bazin PL, Ragert P, Villringer A, Gauthier CJ | 28159689 PERFORM |
| 39 | Age differences in brain signal variability are robust to multiple vascular controls. | Garrett DD, Lindenberger U, Hoge RD, Gauthier CJ | 28860455 PERFORM |
| Title: | The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond | ||||
| Authors: | Villeneuve S, Poirier J, Breitner JCS, Tremblay-Mercier J, Remz J, Raoult JM, Yakoub Y, Gallego-Rudolf J, Qiu T, Valdez AF, Mohammediyan B, Javanray M, Metz A, Sanami S, Ourry V, Wearn A, Pastor-Bernier A, Edde M, Gonneaud J, Strikwerda-Brown C, Tardif CL, Gauthier CJ, Descoteaux M, Dadar M, Vachon-Presseau É, Baril AA, Ducharme S, Montembeault M, Geddes MR, Soucy JP, Rajah N, Laforce R, Bocti C, Davatzikos C, Bellec L, Rosa-Neto P, Baillet S, Evans AC, Collins DL, Chakravarty MM, Blennow K, Zetterberg H, S | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40778177/ | ||||
| DOI: | 10.1101/2025.07.22.25331791 | ||||
| Publication: | medRxiv : the preprint server for health sciences | ||||
| Keywords: | Biomarkers; clinical progression; cognition; data repository; neuroimaging; preclinical; | ||||
| PMID: | 40778177 | Category: | Date Added: | 2025-08-19 | |
| Dept Affiliation: |
PSYCHOLOGY
1 StoP-AD Centre, Douglas Mental Health University Institute, McGill University, Montréal, QC H4H 1R3, Canada. 2 Department of Psychiatry, McGill University, Montréal, QC H3A 1A1, Canada. 3 McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montréal, QC H3A 2B4, Canada. 4 Cerebral Imaging Centre, Douglas Mental Health University Institute, McGill University, Montréal, QC H4H 1R3, Canada. 5 Integrated Program in Neuroscience, McGill University, Montréal, QC H3A 0G4, Canada. 6 Research Center of the CIUSSS-NIM, Hôpital du Sacré-Coeur de Montréal, Montreal, QC H4J 1C5, Canada. 7 Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada. 8 Department of Physics, Concordia University, Montréal, QC H4B 1R6, Canada. 9 Department of Neurology and Neurosurgery, McGill University, Montréal, QC H3A 1A1, Canada. 10 Faculté des sciences, Département d'informatique, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada. 11 Normandie Univ, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", NeuroPresage Team, GIP Cyceron, 14032 Caen, France. 12 School of Psychological Science, The University of Western Australia, Perth, Western Australia 6009, Australia. 13 Department Biomedical Engineering, McGill University, Montréal, QC H3A 2B4, Canada. 14 Centre ÉPIC, Montreal Heart Institute, Montréal, QC H1T 1N6, Canada. 15 Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, QC H3A 1G1, Canada. 16 Department of Anesthesia, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H3G 2M1, Canada. 17 Alan Edwards Center for Research on Pain, McGill University, Montreal, QC H3A 2B4, Canada. 18 Department of Psychology, Toronto Metropolitan University, Toronto, ON M5S 2E5, Canada. 19 Clinique interdisciplinaire de mémoire, CHU de Québec affilié à l'Université Laval, Québec, QC G1V 4G2, Canada. 20 Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5H3, Canada. 21 AI2D Center for AI and Data Science for Integrated Diagnostics, University of Pennsylvania, Philadelphia, PA 19104, USA. 22 Psychology Department, Université de Montréal, Montréal, QC H2V 2S9, Canada. 23 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC H3W 1W5, Canada. 24 Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 431 39 Mölndal, Sweden. 25 Clinical Neurochemistry Lab, Sahlgrenska University Hospital, 43180 Mölndal, Sweden. 26 Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, 75013 Paris, France. 27 Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, Anhui, 230026 P.R. China. 28 Department of Neurodegenerative Disease, University College London Institute of Neurology, London WC1E 6BT, UK. 29 UK Dementia Research Institute at UCL, London NW1 3BT, UK. 30 Hong Kong Center for Neurodegenerative Diseases, InnoHK, 999077 Hong Kong, China. 31 Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA. 32 Department of Physiology and Pharmacology, Université de Montréal, Montréal, QC H3C 3J7, Canada. 33 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 224 41 Lund, Sweden. |
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Description: |
The PREVENT-AD is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now been followed annually for more than 12 years [median follow-up 8.0 years,SD 3.1]. Multimodal MRI, genetic, neurosensory, clinical, cerebrospinal fluid and cognitive data collected until 2017 on 348 participants who agreed to open sharing with the neuroscience community were already available. We now share a new release including 6 years of additional follow-up cognitive data, and additional MRI follow-ups, clinical progression, new longitudinal behavioral and lifestyle measures (questionnaires, actigraphy), longitudinal AD plasma biomarkers, amyloid-beta and tau PET, magnetoencephalography, as well as neuroimaging analytic measures from all MRI modalities. We describe the PREVENT-AD study, the data shared with the global research community as well as the model we created to sustain longitudinal follow-ups while also allowing new innovative data collection. |
