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PubMed Publications| Keyword search (4,163 papers available) |  |
"Goldfield GS" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | The BDNF Val66Met polymorphism and health-related quality of life in youth with obesity | Goldfield GS; Cameron JD; Sigal RJ; Kenny GP; Prud' homme D; Ngu M; Alberga AS; Doucette S; Goldfield DB; Tulloch H; Thai H; Simas KR; Walsh J; | 38997217 HKAP |
| 2 | Exploring the association between internalized weight bias and mental health among Canadian adolescents | Lucibello KM; Goldfield GS; Alberga AS; Leatherdale ST; Patte KA; | 38676448 HKAP |
| 3 | Effects of the HEARTY exercise randomized controlled trial on eating behaviors in adolescents with obesity | Alberga AS; Edache IY; Sigal RJ; von Ranson KM; Russell-Mayhew S; Kenny GP; Doucette S; Prud' homme D; Hadjiyannakis S; Cameron JD; Goldfield GS; | 37034563 HKAP |
| 4 | Associations of the BDNF Val66Met Polymorphism With Body Composition, Cardiometabolic Risk Factors, and Energy Intake in Youth With Obesity: Findings From the HEARTY Study | Goldfield GS; Walsh J; Sigal RJ; Kenny GP; Hadjiyannakis S; De Lisio M; Ngu M; Prud' homme D; Alberga AS; Doucette S; Goldfield DB; Cameron JD; | 34867148 IMAGING |
| 5 | The Association Between Weight-Based Teasing from Peers and Family in Childhood and Depressive Symptoms in Childhood and Adulthood: A Systematic Review. | Szwimer E, Mougharbel F, Goldfield GS, Alberga AS | 32002762 HKAP |
| 6 | Understanding low adherence to an exercise program for adolescents with obesity: the HEARTY trial. | Alberga AS, Sigal RJ, Sweet SN, Doucette S, Russell-Mayhew S, Tulloch H, Kenny GP, Prud'homme D, Hadjiyannakis S, Goldfield GS | 31687168 HKAP |
| 7 | Edmonton Obesity Staging System for Pediatrics, quality of life and fitness in adolescents with obesity. | Kakon GA, Hadjiyannakis S, Sigal RJ, Doucette S, Goldfield GS, Kenny GP, Prud'homme D, Buchholz A, Lamb M, Alberga AS | 31687169 HKAP |
| 8 | Corrigendum to "Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial" Physiology & Behavior, Volume 191, 1 July 2018, Pages 138-145. | Goldfield GS, Kenny GP, Prud'homme D, Holcik M, Alberga AS, Fahnestock M, Cameron JD, Doucette S, Hadjiyannakis S, Tulloch H, Tremblay MS, Walsh J, Guerin E, Gunnell KE, D'Angiulli A, Sigal RJ | 30428994 PSYCHOLOGY |
| 9 | Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomized Controlled Trial. | Walsh JJ, D'Angiulli A, Cameron JD, Sigal RJ, Kenny GP, Holcik M, Doucette S, Alberga AS, Prud'homme D, Hadjiyannakis S, Gunnell K, Goldfield GS | 30363954 HKAP |
| 10 | Interindividual variability and individual responses to exercise training in adolescents with obesity. | Walsh JJ, Bonafiglia JT, Goldfield GS, Sigal RJ, Kenny GP, Doucette S, Hadjiyannakis S, Alberga AS, Prud'homme D, Gurd BJ | 31121100 HKAP |
| Title: | Associations of the BDNF Val66Met Polymorphism With Body Composition, Cardiometabolic Risk Factors, and Energy Intake in Youth With Obesity: Findings From the HEARTY Study | ||||
| Authors: | Goldfield GS, Walsh J, Sigal RJ, Kenny GP, Hadjiyannakis S, De Lisio M, Ngu M, Prud' homme D, Alberga AS, Doucette S, Goldfield DB, Cameron JD | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/34867148/ | ||||
| DOI: | 10.3389/fnins.2021.715330 | ||||
| Publication: | Frontiers in neuroscience | ||||
| Keywords: | BDNF; Val66Met; adolescents; cardiometabolic risk; energy intake; gene; obesity; | ||||
| PMID: | 34867148 | Category: | Date Added: | 2021-12-06 | |
| Dept Affiliation: |
IMAGING
1 Healthy Active Living and Obesity Research Group, Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada. 2 Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada. 3 School of Human Kinetics, University of Ottawa, Ottawa, ON Canada. 4 Department of Kinesiology, McMaster University, Hamilton, ON, Canada. 5 Department of Medicine, Cardiac Sciences and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. 6 Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada. 7 Centre for Healthy Active Living, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada. 8 President and Vice Chancellor, University of Moncton, Moncton, NB, Canada. 9 Department of Kinesiology, Concordia University, Montreal, QC, Canada. |
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Description: |
The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is functionally related to BDNF, and is associated with obesity and metabolic complications in adults, but limited research exists among adolescents. This study comparatively examined carriers and non-carriers of the BDNF Val66Met polymorphism on body composition, energy intake, and cardiometabolic profile among adolescents with obesity. The sample consisted of 187 adolescents with obesity; 99 were carriers of the homozygous Val (G/G) alleles and 88 were carriers of the Val/Met (G/A) or Met (A/A) alleles. Cardiometabolic profile and DNA were quantified from fasted blood samples. Body composition was assessed by magnetic resonance imaging (MRI). Compared to carriers of the homozygous Val (G/G) allele, carriers of the Val/Met (G/A) or Met/Met (A/A) variants exhibited significantly higher protein (p = 0.01) and fat (p = 0.05) intake, C-Reactive protein (p = 0.05), and a trend toward higher overall energy intake (p = 0.07), fat-free mass (p = 0.07), and lower HDL-C (p = 0.07) Results showed for the first time that among youth with obesity, carriers of the Val66Met BDNF Met-alleles exhibited significantly higher C-reactive protein and energy intake in the form of fat and protein compared to Val-allele carriers, thereby providing support for the possible role of BDNF in appetite, weight, and metabolic regulation during adolescence. Clinical Trial Registration: http://clinicaltrials.gov/, identifier NCT00195858. |
