Keyword search (4,163 papers available)

"Kostikov A" Authored Publications:

Title Authors PubMed ID
1 Brain PET Imaging in Small Animals: Tracer Formulation, Data Acquisition, Image Reconstruction, and Data Analysis Bdair H; Kang MS; Ottoy J; Aliaga A; Kunach P; Singleton TA; Blinder S; Soucy JP; Leyton M; Rosa-Neto P; Kostikov A; 38006502
PERFORM
2 Dosimetry of [18F]TRACK, the first PET tracer for imaging of TrkB/C receptors in humans Thiel A; Kostikov A; Ahn H; Daoud Y; Soucy JP; Blinder S; Jaworski C; Wängler C; Wängler B; Juengling F; Enger SA; Schirrmacher R; 37870640
PERFORM
3 Radiosynthesis and In Vivo Evaluation of Four Positron Emission Tomography Tracer Candidates for Imaging of Melatonin Receptors Bdair H; Singleton TA; Ross K; Jolly D; Kang MS; Aliaga A; Tuznik M; Kaur T; Yous S; Soucy JP; Massarweh G; Scott PJH; Koeppe R; Spadoni G; Bedini A; Rudko DA; Gobbi G; Benkelfat C; Rosa-Neto P; Brooks AF; Kostikov A; 35420022
PERFORM
4 Development of "[11C]kits" for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography. Jolly D, Hopewell R, Kovacevic M, Li QY, Soucy JP, Kostikov A 28038410
PERFORM
5 Effect of (Z)-isomer content on [11C]ABP688 binding potential in humans. Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M 30607444
CSBN
6 Quantification of brain cholinergic denervation in Alzheimer's disease using PET imaging with [18F]-FEOBV. Aghourian M, Legault-Denis C, Soucy JP, Rosa-Neto P, Gauthier S, Kostikov A, Gravel P, Bédard MA 28894304
PERFORM

 

Title:Development of "[11C]kits" for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography.
Authors:Jolly DHopewell RKovacevic MLi QYSoucy JPKostikov A
Link:https://www.ncbi.nlm.nih.gov/pubmed/28038410?dopt=Abstract
DOI:10.1016/j.apradiso.2016.11.020
Publication:Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Keywords:Automated radiolabelingCarbon-11 radiotracersKit-like productionPositron Emission Tomography
PMID:28038410 Category:Appl Radiat Isot Date Added:2019-06-20
Dept Affiliation: PERFORM
1 Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, QC, Canada H3A2B4.
2 Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, QC, Canada H3A2B4; Concordia-PERFORM Centre, Concordia University, Montreal, Canada.

Description:

Development of "[11C]kits" for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography.

Appl Radiat Isot. 2017 Mar;121:76-81

Authors: Jolly D, Hopewell R, Kovacevic M, Li QY, Soucy JP, Kostikov A

Abstract

Translation of carbon-11 labeled PET tracers to clinical settings is currently impeded by the technical difficulties associated with [11C]CO2 conversion into the highly reactive methylating agents [11C]CH3I and [11C]CH3OTf using automated modules relying on stationary valves. Here we describe development of the first in its kind "[11C]kit" for production of carbon-11 radiotracer using disposable manifolds. This method proved to be very reliable and allows for consecutive production of PET tracers with minimal intervals between the syntheses.

PMID: 28038410 [PubMed - indexed for MEDLINE]





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