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PubMed Publications| Keyword search (4,163 papers available) |  |
"Krull KR" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Symptom burden, healthcare utilization, and risky behaviors in survivors of the childhood cancer survivor study (CCSS): an observation cohort study | Webster R; Srivastava DK; Xie L; Darji H; Liu W; McGrady ME; Brinkman TM; Alberts NM; Ness KK; Fuemmeler B; Kunin-Batson AS; Huang IC; Armstrong GT; Howell RM; Green DM; Yasui Y; Krull KR; | 41340862 PSYCHOLOGY |
| 2 | Intolerance of uncertainty, psychological symptoms, and pain in long-term childhood cancer survivors: a report from the Childhood Cancer Survivor Study | Alberts NM; Stratton KL; Leisenring WM; Pizzo A; Lamoureux É; Alschuler K; Flynn J; Krull KR; Jibb LA; Nathan PC; Olgin JE; Stinson JN; Armstrong GT; | 40699439 PSYCHOLOGY |
| 3 | Fear of Cancer Recurrence in Adult Survivors of Childhood Cancer | Pizzo A; Leisenring WM; Stratton KL; Lamoureux É; Flynn JS; Alschuler K; Krull KR; Jibb LA; Nathan PC; Olgin JE; Stinson JN; Armstrong GT; Alberts NM; | 39361286 PSYCHOLOGY |
| 4 | Neuropathic pain and neurocognitive functioning in children treated for acute lymphoblastic leukemia | Partanen M; Alberts NM; Conklin HM; Krull KR; Pui CH; Anghelescu DA; Jacola LM; | 34813516 CONCORDIA |
| 5 | Change in Pain Status and Subsequent Opioid and Marijuana Use Among Long-Term Adult Survivors of Childhood Cancer. | Huang IC, Alberts NM, Buckley MG, Li Z, Ehrhardt MJ, Brinkman TM, Allen J, Krull KR, Klosky JL, Greene WL, Srivastava DK, Robison LL, Hudson MM, Anghelescu DL | 33409451 PSYCHOLOGY |
| 6 | Wearable Respiratory Monitoring and Feedback for Chronic Pain in Adult Survivors of Childhood Cancer: A Feasibility Randomized Controlled Trial From the Childhood Cancer Survivor Study. | Alberts NM, Leisenring WM, Flynn JS, Whitton J, Gibson TM, Jibb L, McDonald A, Ford J, Moraveji N, Dear BF, Krull KR, Robison LL, Stinson JN, Armstrong GT | 33147073 CONCORDIA |
| 7 | Pain in long-term survivors of childhood cancer: A systematic review of the current state of knowledge and a call to action from the Children's Oncology Group. | Schulte FSM, Patton M, Alberts NM, Kunin-Batson A, Olson-Bullis BA, Forbes C, Russell KB, Neville A, Heathcote LC, Karlson CW, Racine NM, Charnock C, Hocking MC, Banerjee P, Tutelman PR, Noel M, Krull KR | 33112416 PSYCHOLOGY |
| Title: | Symptom burden, healthcare utilization, and risky behaviors in survivors of the childhood cancer survivor study (CCSS): an observation cohort study | ||||
| Authors: | Webster R, Srivastava DK, Xie L, Darji H, Liu W, McGrady ME, Brinkman TM, Alberts NM, Ness KK, Fuemmeler B, Kunin-Batson AS, Huang IC, Armstrong GT, Howell RM, Green DM, Yasui Y, Krull KR | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/41340862/ | ||||
| DOI: | 10.1016/j.eclinm.2025.103657 | ||||
| Publication: | EClinicalMedicine | ||||
| Keywords: | Childhood cancer survivors; Healthcare utilization; Risky health behaviors; Symptom burden; | ||||
| PMID: | 41340862 | Category: | Date Added: | 2025-12-04 | |
| Dept Affiliation: |
PSYCHOLOGY
1 Department of Psychology and Biobehavioral Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. 2 Comprehensive Cancer Center, St. Jude Children's Research Hospital, Memphis, TN, USA. 3 Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA. 4 Phastar Inc., Cambridge, MA, USA. 5 Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. 6 Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. 7 Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA. 8 Department of Psychology, Concordia University, Montreal, QC, Canada. 9 Virginia Commonwealth University Massey Comprehensive Cancer Center, Richmond, VA, USA. 10 University of Minnesota Medical School, Minneapolis, MI, USA. 11 The University of Texas MD Anderson Cancer Center, Houston, TX, USA. |
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Description: |
Background: Childhood cancer survivors face physical, psychological, and neurological symptoms that contribute to risky health behaviors and increased healthcare utilization. Traditional survivorship care models overlook risk associated with this symptom burden. The current study examined symptoms phenotypes to identify high-risk groups. Methods: Five-year survivors (N = 17,231; Mean [standard deviation] age = 27.4 [5.98]; 80% non-Hispanic White; 48% female) from the Childhood Cancer Survivor Study (NCT01120353) self-reported symptoms and risky behavior at baseline and first follow-up (original cohort data collection: baseline 1994-1998 and follow-up 2002-2004; expansion cohort: baseline 2008-2010 and follow-up 2014-2016). Medical records were extracted through chart review. Chronic health conditions (CHCs) were graded according to common terminology criteria for adverse events criteria. Latent class analysis derived symptom phenotypes. Findings: Five phenotypes emerged: 1) Low Burden (63.1%); 2) Cardio-Pulmonary-Pain (5.3%) 3); Neurologic-Pain (10.6%); 4) Psychological Distress-Pain (13.3%); 5) Global burden (7.7%). Compared to survivors with Low Burden, those in other symptom phenotypes were older, female, had lower education, no health insurance, smoked cigarettes, were physically inactive, and had = grade 3 CHC (all ps < 0.05). Survivors in symptom phenotypes were at-risk for future emergency room use (all ps < 0.05). Risk for future physical inactivity was higher in Cardio-Pulmonary-Pain (OR = 1.19, CI = 1.09, 1.31), Global (OR = 1.12, CI = 1.02, 1.22), and Neurologic-Pain (OR = 1.18, CI = 1.10, 1.27) phenotypes. Cigarette use was higher in Cardio-Pulmonary-Pain (OR = 1.62, CI = 1.08, 2.42) and (Global OR = 1.65, CI = 1.17, 2.31) phenotypes. Interpretation: Symptom phenotyping identified groups at-risk for future risky health behaviors, which was not explained alone by diagnosis or CHCs. Integrating symptom assessments may guide interventions to improve health outcomes. Funding: The work was supported by the National Cancer Institute (U24 CA055727, PI: GT Armstrong). Support to St. Jude Children's Research Hospital was also provided by the National Cancer Institute Cancer Center Support grant (P30 CA021765, PI: CWM Roberts) and by the American Lebanese Syrian Associated Charities. |
