BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,163 papers available) |  |
"Lamarre-Cliche M" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer's Disease | Badji A; de la Colina AN; Boshkovski T; Sabra D; Karakuzu A; Robitaille-Grou MC; Gros C; Joubert S; Bherer L; Lamarre-Cliche M; Stikov N; Gauthier CJ; Cohen-Adad J; Girouard H; | 32741837 PERFORM |
| 2 | Hypertension Canada's 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension. | Leung AA, Nerenberg K, Daskalopoulou SS, McBrien K, Zarnke KB, Dasgupta K, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tobe SW, Ruzicka M, Burns KD, Vallée M, Prasad GV, Lebel M, Feldman RD, Selby P, Pipe A, Schiffrin EL, McFarlane PA, Oh P, Hegele RA, Khara M, Wilson TW, Penner SB, Burgess E, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell NR, Moe GW, Howlett JG, Boulanger JM, Prebtani A, Laroc | 27118291 HKAP |
| 3 | Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults. | Leung AA, Daskalopoulou SS, Dasgupta K, McBrien K, Butalia S, Zarnke KB, Nerenberg K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tran KC, Tobe SW, Ruzicka M, Burns KD, Vallée M, Prasad GVR, Gryn SE, Feldman RD, Selby P, Pipe A, Schiffrin EL, McFarlane PA, Oh P, Hegele RA, Khara M, Wilson TW, Penner SB, Burgess E, Sivapalan P, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell | 28449828 HKAP |
| 4 | Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. | Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Padwal RS, Tran KC, Grover S, Rabkin SW, Moe GW, Howlett JG, Lindsay P, Hill MD, Sharma M, Field T, Wein TH, Shoamanesh A, Dresser GK, Hamet P, Herman RJ, Burgess E, Gryn SE, Grégoire JC, Lewanczuk R, Poirier L, Campbell TS, Feldman RD, Lavoie KL, Tsuyuki RT, Honos G, Prebtani APH, Kline G, Schiffrin EL, Don-Wauchope A, Tobe SW, Gilbert RE, | 29731013 NA |
| Title: | A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer's Disease | ||||
| Authors: | Badji A, de la Colina AN, Boshkovski T, Sabra D, Karakuzu A, Robitaille-Grou MC, Gros C, Joubert S, Bherer L, Lamarre-Cliche M, Stikov N, Gauthier CJ, Cohen-Adad J, Girouard H | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/32741837/ | ||||
| DOI: | 10.3233/JAD-200668 | ||||
| Publication: | Journal of Alzheimer' s disease : JAD | ||||
| Keywords: | Aging; Alzheimer'; s disease; arterial spin labelling; arterial stiffness; corpus callosum; diffusion weighted imaging; | ||||
| PMID: | 32741837 | Category: | Date Added: | 2020-08-18 | |
| Dept Affiliation: |
PERFORM
1 NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada. 2 Centre de recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montreal, QC, Canada. 3 Department of Neurosciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. 4 Groupe de Recherche sur le Système Nerveux Central (GRSNC), Université de Montréal, Montreal, QC, Canada. 5 Centre interdisciplinaire de recherche sur le cerveau et l'apprentissage (CIRCA), Université de Montréal, Montreal, QC, Canada. 6 Department of Biomedical Sciences, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. 7 Montreal Heart Institute, Montreal, QC, Canada. 8 PERFORM Centre, Concordia University, Montreal, QC, Canada. 9 Department of Psychology, Faculty of Arts and Sciences, Université de Montréal, Montreal, QC, Canada. 10 Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. 11 Institut de Recherches Cliniques de Montréal, Université de Montréal, Montreal, QC, Canada. 12 Physics Department, Concordia University, Montreal, QC, Canada. 13 Functional Neuroimaging Unit, Centre de recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Université de Montréal, Montreal, QC, Canada. 14 Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada. |
||||
Description: |
Background: Vascular risk factors such as arterial stiffness play an important role in the etiology of Alzheimer's disease (AD), presumably due to the emergence of white matter lesions. However, the impact of arterial stiffness to white matter structure involved in the etiology of AD, including the corpus callosum remains poorly understood. Objective: The aims of the study are to better understand the relationship between arterial stiffness, white matter microstructure, and perfusion of the corpus callosum in older adults. Methods: Arterial stiffness was estimated using the gold standard measure of carotid-femoral pulse wave velocity (cfPWV). Cognitive performance was evaluated with the Trail Making Test part B-A. Neurite orientation dispersion and density imaging was used to obtain microstructural information such as neurite density and extracellular water diffusion. The cerebral blood flow was estimated using arterial spin labelling. Results: cfPWV better predicts the microstructural integrity of the corpus callosum when compared with other index of vascular aging (the augmentation index, the systolic blood pressure, and the pulse pressure). In particular, significant associations were found between the cfPWV, an alteration of the extracellular water diffusion, and a neuronal density increase in the body of the corpus callosum which was also correlated with the performance in cognitive flexibility. Conclusion: Our results suggest that arterial stiffness is associated with an alteration of brain integrity which impacts cognitive function in older adults. |
