Keyword search (4,164 papers available)

"Li G" Authored Publications:

Title Authors PubMed ID
1 Prevalence and characteristics of neuropathic pain in adolescent survivors of childhood cancer Mesaroli G; Olaizola S; Nair A; Nishat F; Pizzo A; Nathan PC; Alberts NM; Stinson JN; 40999274
PSYCHOLOGY
2 Alzheimer's early detection in post-acute COVID-19 syndrome: a systematic review and expert consensus on preclinical assessments Vandersteen C; Plonka A; Manera V; Sawchuk K; Lafontaine C; Galery K; Rouaud O; Bengaied N; Launay C; Guérin O; Robert P; Allali G; Beauchet O; Gros A; 37416323
CONCORDIA
3 Motor and cognitive outcomes of neonates with low birth weight in Brazil: a systematic review and meta-analysis Radaelli G; Leal-Conceição E; Kalil Neto F; Taurisano MRG; Majolo F; Bruzzo FTK; Booij L; Nunes ML; 36863403
PSYCHOLOGY
4 Frailty, e-health and prevention of late-onset Alzheimer disease and related disorders: it is time to take action Beauchet O; Galery K; Lafontaine C; Sawchuk K; Plonka A; Gros A; Allali G; 35334089
CONCORDIA
5 Spatiotemporal analysis of land use pattern and stream water quality in southern Alberta, Canada Chen Z; An C; Tan Q; Tian X; Li G; Zhou Y; 34214919
ENCS
6 Disaster-related prenatal maternal stress predicts HPA reactivity and psychopathology in adolescent offspring: Project Ice Storm. Yong Ping E, Laplante DP, Elgbeili G, Jones SL, Brunet A, King S 32442863
PSYCHOLOGY
7 Reduced fear-of-self is associated with improvement in concerns related to repugnant obsessions in obsessive-compulsive disorder. Aardema F, Wong SF, Audet JS, Melli G, Baraby LP 30548626
PSYCHOLOGY
8 Brain gray matter volume associations with gait speed and related structural covariance networks in cognitively healthy individuals and in patients with mild cognitive impairment: A cross-sectional study. Beauchet O, Montembeault M, Barden JM, Szturm T, Bherer L, Liu-Ambrose T, Chester VL, Li K, Helbostad JL, Allali G, Canadian Gait Consortium 31075383
PSYCHOLOGY
9 Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial. Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G, Canadian Gait Consortium 27568453
PERFORM
10 Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults. Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium 27785698
PERFORM

 

Title:Alzheimer's early detection in post-acute COVID-19 syndrome: a systematic review and expert consensus on preclinical assessments
Authors:Vandersteen CPlonka AManera VSawchuk KLafontaine CGalery KRouaud OBengaied NLaunay CGuérin ORobert PAllali GBeauchet OGros A
Link:https://pubmed.ncbi.nlm.nih.gov/37416323/
DOI:10.3389/fnagi.2023.1206123
Publication:Frontiers in aging neuroscience
Keywords:Alzheimer's diseasebiomarkersearly diagnosisolfactory disorderspost-acute COVID-19 syndrome
PMID:37416323 Category: Date Added:2023-07-07
Dept Affiliation: CONCORDIA

Description:

Introduction: The risk of developing Alzheimer's disease (AD) in older adults increasingly is being discussed in the literature on Post-Acute COVID-19 Syndrome (PACS). Remote digital Assessments for Preclinical AD (RAPAs) are becoming more important in screening for early AD, and should always be available for PACS patients, especially for patients at risk of AD. This systematic review examines the potential for using RAPA to identify impairments in PACS patients, scrutinizes the supporting evidence, and describes the recommendations of experts regarding their use.

Methods: We conducted a thorough search using the PubMed and Embase databases. Systematic reviews (with or without meta-analysis), narrative reviews, and observational studies that assessed patients with PACS on specific RAPAs were included. The RAPAs that were identified looked for impairments in olfactory, eye-tracking, graphical, speech and language, central auditory, or spatial navigation abilities. The recommendations' final grades were determined by evaluating the strength of the evidence and by having a consensus discussion about the results of the Delphi rounds among an international Delphi consensus panel called IMPACT, sponsored by the French National Research Agency. The consensus panel included 11 international experts from France, Switzerland, and Canada.

Results: Based on the available evidence, olfaction is the most long-lasting impairment found in PACS patients. However, while olfaction is the most prevalent impairment, expert consensus statements recommend that AD olfactory screening should not be used on patients with a history of PACS at this point in time. Experts recommend that olfactory screenings can only be recommended once those under study have reported full recovery. This is particularly important for the deployment of the olfactory identification subdimension. The expert assessment that more long-term studies are needed after a period of full recovery, suggests that this consensus statement requires an update in a few years.

Conclusion: Based on available evidence, olfaction could be long-lasting in PACS patients. However, according to expert consensus statements, AD olfactory screening is not recommended for patients with a history of PACS until complete recovery has been confirmed in the literature, particularly for the identification sub-dimension. This consensus statement may require an update in a few years.





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