Keyword search (4,164 papers available)

"Li K" Authored Publications:

Title Authors PubMed ID
1 ADPv2: A hierarchical histological tissue type-annotated dataset for potential biomarker discovery of colorectal disease Yang Z; Li K; Ramandi SG; Brassard P; Khellaf A; Trinh VQ; Zhang J; Chen L; Rowsell C; Varma S; Plataniotis K; Hosseini MS; 41658283
ENCS
2 Dementia Care Research and Psychosocial Factors Mancor E; Montero-Odasso M; Bherer L; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Li K; 41448628
CONCORDIA
3 Clinical Manifestations Gagnon C; Montero-Odasso M; Zou G; Speechley MR; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li K; Fraser S; Pieruccini-Faria F; Burhan AM; Berryman N; Lussier M; Son S; Shoemaker JK; Bherer L; 41447475
CONCORDIA
4 Public Health Pieruccini-Faria F; Son S; Liu-Ambrose T; Burhan AM; Almeida QJ; Middleton LE; Li K; Fraser S; Bherer L; Montero-Odasso M; 41435121
CONCORDIA
5 Cardiometabolic disease risk in relation to objectively measured physical activity, sedentary behaviour in South African adults with knee and hip osteoarthritis Kaoje YS; Mokete L; Dafkin C; Pietrzak J; Sikhauli K; Frimpong E; Meiring RM; 39162078
HKAP
6 The impact of cognitive-motor interference on balance and gait in hearing-impaired older adults: a systematic review Wunderlich A; Wollesen B; Asamoah J; Delbaere K; Li K; 38914940
PSYCHOLOGY
7 Advancements in Sensor Technologies and Control Strategies for Lower-Limb Rehabilitation Exoskeletons: A Comprehensive Review Yao Y; Shao D; Tarabini M; Moezi SA; Li K; Saccomandi P; 38675301
ENCS
8 At-home computerized executive-function training to improve cognition and mobility in normal-hearing adults and older hearing aid users: a multi-centre, single-blinded randomized controlled trial Downey R; Gagné N; Mohanathas N; Campos JL; Pichora-Fuller KM; Bherer L; Lussier M; Phillips NA; Wittich W; St-Onge N; Gagné JP; Li K; 37864139
PERFORM
9 Droplet digital microfluidic system for screening filamentous fungi based on enzymatic activity Samlali K; Alves CL; Jezernik M; Shih SCC; 36438986
BIOLOGY
10 Community-led risk analysis of direct-to-consumer whole-genome sequencing Samlali K; Thornbury M; Venter A; 35939839
ENCS
11 Uncovering global-scale risks from commercial chemicals in air Liu Q; Li L; Zhang X; Saini A; Li W; Hung H; Hao C; Li K; Lee P; Wentzell JJB; Huo C; Li SM; Harner T; Liggio J; 34912090
CHEMBIOCHEM
12 Digital Microfluidics Chips for the Execution and Real-Time Monitoring of Multiple Ribozymatic Cleavage Reactions Davis AN; Samlali K; Kapadia JB; Perreault J; Shih SCC; Kharma N; 34514224
BIOLOGY
13 The effect of step-feeding distribution ratio on high concentration perchlorate removal performance in ABR system with heterotrophic combined sulfur autotrophic process. Li H, Li K, Guo J, Chen Z, Han Y, Song Y, Lu C, Hou Y, Zhang D, Zhang Y 33485237
ENCS
14 Evaluation of System Modelling Techniques for Waste Identification in Lean Healthcare Applications. Alkaabi M, Simsekler MCE, Jayaraman R, Al Kaf A, Ghalib H, Quraini D, Ellahham S, Tuzcu EM, Demirli K 33447104
ENCS
15 CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; 33094146
CRDH
16 One Cell, One Drop, One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation. Samlali K, Ahmadi F, Quach ABV, Soffer G, Shih SCC 32705796
BIOLOGY
17 Reflective and Reflexive Stress Responses of Older Adults to Three Gaming Experiences In Relation to Their Cognitive Abilities: Mixed Methods Crossover Study. Khalili-Mahani N, Assadi A, Li K, Mirgholami M, Rivard ME, Benali H, Sawchuk K, De Schutter B 32213474
PERFORM
18 Dual Reduction/Acid-Responsive Disassembly and Thermoresponsive Tunability of Degradable Double Hydrophilic Block Copolymer. Maruya-Li K, Shetty C, Moini Jazani A, Arezi N, Oh JK 32118189
CHEMBIOCHEM
19 Facile Strategies to Synthesize Dual Location Dual Acidic pH/Reduction-Responsive Degradable Block Copolymers Bearing Acetal/Disulfide Block Junctions and Disulfide Pendants. Jazani AM, Arezi N, Maruya-Li K, Jung S, Oh JK 31459031
CHEMBIOCHEM
20 Testing continuity and activity variables as predictors of positive and negative affect in retirement. Pushkar D, Chaikelson J, Conway M, Etezadi J, Giannopoulus C, Li K, Wrosch C 19875749
PSYCHOLOGY
21 A Crowdsensing Based Analytical Framework for Perceptional Degradation of OTT Web Browsing. Li K, Wang H, Xu X, Du Y, Liu Y, Ahmad MO 29762493
ENCS
22 Guidelines for Gait Assessments in the Canadian Consortium on Neurodegeneration in Aging (CCNA). Cullen S, Montero-Odasso M, Bherer L, Almeida Q, Fraser S, Muir-Hunter S, Li K, Liu-Ambrose T, McGibbon CA, McIlroy W, Middleton LE, Sarquis-Adamson Y, Beauchet O, McFadyen BJ, Morais JA, Camicioli R, Canadian Gait and Cognition Network 29977431
ENCS
23 An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting. Ahmadi F, Samlali K, Vo PQN, Shih SCC 30633267
ENCS
24 A combined heterotrophic and sulfur-based autotrophic process to reduce high concentration perchlorate via anaerobic baffled reactors: Performance advantages of a step-feeding strategy. Li K, Guo J, Li H, Han Y, Chen Z, Song Y, Xing Y, Zhang C 30738356
ENCS
25 Effects of pool size and spacing on burning rate and flame height of two square heptane pool fires. Wan H, Gao Z, Ji J, Zhang Y, Li K, Wang L 30776594
ENCS
26 Big Data-Driven Cellular Information Detection and Coverage Identification. Wang H, Xie S, Li K, Ahmad MO 30813353
ENCS
27 SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L 29661156
PERFORM
28 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano 26799652
NA
29 A cross-sectional analysis on the effects of age on dual tasking in typically developing children. Saxena S, Majnemer A, Li K, Beauchamp M, Gagnon I 30506524
PSYCHOLOGY
30 Brain gray matter volume associations with gait speed and related structural covariance networks in cognitively healthy individuals and in patients with mild cognitive impairment: A cross-sectional study. Beauchet O, Montembeault M, Barden JM, Szturm T, Bherer L, Liu-Ambrose T, Chester VL, Li K, Helbostad JL, Allali G, Canadian Gait Consortium 31075383
PSYCHOLOGY

 

Title:One Cell, One Drop, One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation.
Authors:Samlali KAhmadi FQuach ABVSoffer GShih SCC
Link:https://www.ncbi.nlm.nih.gov/pubmed/32705796
DOI:10.1002/smll.202002400
Publication:Small (Weinheim an der Bergstrasse, Germany)
Keywords:digital microfluidicsdroplet microfluidicsgene-editingsingle-celltransfection
PMID:32705796 Category:Small Date Added:2020-07-27
Dept Affiliation: BIOLOGY
1 Department of Electrical and Computer Engineering, Concordia University, Montréal, Québec, H3G 1M8, Canada.
2 Centre for Applied Synthetic Biology, Concordia University, Montréal, Québec, H4B 1R6, Canada.
3 Department of Biology, Concordia University, Montréal, Québec, H4B 1R6, Canada.

Description:

One Cell, One Drop, One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation.

Small. 2020 Jul 23;:e2002400

Authors: Samlali K, Ahmadi F, Quach ABV, Soffer G, Shih SCC

Abstract

Generating a stable knockout cell line is a complex process that can take several months to complete. In this work, a microfluidic method that is capable of isolating single cells in droplets, selecting successful edited clones, and expansion of these isoclones is introduced. Using a hybrid microfluidics method, droplets in channels can be individually addressed using a co-planar electrode system. In the hybrid microfluidics device, it is shown that single cells can be trapped and subsequently encapsulate them on demand into pL-sized droplets. Furthermore, droplets containing single cells are either released, kept in the traps, or merged with other droplets by the application of an electric potential to the electrodes that is actuated through an in-house user interface. This high precision control is used to successfully sort and recover single isoclones to establish monoclonal cell lines, which is demonstrated with a heterozygous NCI-H1299 lung squamous cell population resulting from loss-of-function eGFP and RAF1 gene knockout transfections.

PMID: 32705796 [PubMed - as supplied by publisher]





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