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PubMed Publications| Keyword search (4,164 papers available) |  |
"Li L" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | A Fully Virtual Graded Exertion Test Is Safe and Feasible in Symptomatic and Asymptomatic Children With Concussion | Coupal J; Shabanova D; Gagnon I; Grilli L; Beaulieu C; Teel E; | 41816309 SOH |
| 2 | Organic chemicals of Arctic concern in Russian coastal seas | Min XZ; Zhang X; Xie ZY; Nikolaev A; Vorkamp K; Ma JM; Reiersen LO; Li L; Cai MH; Ren NQ; Li YF; Zhang ZF; Kallenborn R; Muir D; | 41571477 CHEMBIOCHEM |
| 3 | Personalized biomarkers of multiscale functional alterations in temporal lobe epilepsy | Xie K; Sahlas E; Ngo A; Chen J; Arafat T; Royer J; Zhou Y; Rodríguez-Cruces R; Dascal A; Caldairou B; Fadaie F; Barnett A; Audrain S; Larivière S; Caciagli L; Pana R; Weil AG; Grova C; Frauscher B; Schrader DV; Zhang Z; Concha L; Bernasconi A; Bernasconi N; Bernhardt BC; | 41258102 SOH |
| 4 | Multiphase OH Oxidation of Bisphenols: Chemical Transformation and Persistence in the Environment | Yu J; Wu B; Peng C; Wentzell J; Wheeler MJ; Osagu JO; Zhang X; Li L; Abbatt JPD; Liggio J; | 40569786 CHEMBIOCHEM |
| 5 | Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia | Barbaux L; Perrault AA; Cross NE; Weiner OM; Es-Sounni M; Pomares FB; Tarelli L; McCarthy M; Maltezos A; Smith D; Gong K; O' Byrne J; Yue V; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Gilbert S; Tannenbaum C; Gouin JP; Dang-Vu TT; | 40570297 CSBN |
| 6 | A Concussion Management Policy Change Promoted Earlier Initiation of Rehabilitation Services and Improved Clinical Recovery Outcomes in Concussion | Teel EF; Dobney D; Friedman D; Grilli L; Beaulieu C; Gagnon IJ; | 39798559 HKAP |
| 7 | Exploring global oceanic persistence and ecological effects of legacy persistent organic pollutants across five decades | Zhang X; Li L; Xie Z; Ma J; Li YF; Cai M; Ren NQ; Kallenborn R; Zhang ZF; Zhang X; C G Muir D; | 39321284 CHEMBIOCHEM |
| 8 | A Pilot Randomized Trial of Combined Cognitive-Behavioral Therapy and Exercise Training Versus Exercise Training Alone for the Management of Chronic Insomnia in Obstructive Sleep Apnea | Cammalleri A; Perrault AA; Hillcoat A; Carrese-Chacra E; Tarelli L; Patel R; Baltzan M; Chouchou F; Dang-Vu TT; Gouin JP; Pepin V; | 38663849 PERFORM |
| 9 | Methodological approach to sleep state misperception in insomnia disorder: Comparison between multiple nights of actigraphy recordings and a single night of polysomnography recording | Maltezos A; Perrault AA; Walsh NA; Phillips EM; Gong K; Tarelli L; Smith D; Cross NE; Pomares FB; Gouin JP; Dang-Vu TT; | 38325157 HKAP |
| 10 | Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis | Mascheretti S; Forni D; Lampis V; Fumagalli L; Paquin S; Andlauer TFM; Wang W; Dionne G; Brendgen MR; Vitaro F; Ouellet-Morin I; Rouleau G; Gouin JP; Côté S; Tremblay RE; Turecki G; Garon-Carrier G; Boivin M; Battaglia M; | 37146008 PSYCHOLOGY |
| 11 | A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols | Lu H; Li W; Whiteway M; Wang H; Zhu S; Ji Z; Feng Y; Yan L; Fang T; Li L; Ni T; Zhang X; Lv Q; Ding Z; Qiu L; Zhang D; Jiang Y; | 36475771 BIOLOGY |
| 12 | Effects of cognitive behavioral therapy for insomnia on subjective and objective measures of sleep and cognition | Perrault AA; Pomares FB; Smith D; Cross NE; Gong K; Maltezos A; McCarthy M; Madigan E; Tarelli L; McGrath JJ; Savard J; Schwartz S; Gouin JP; Dang-Vu TT; | 35691208 PERFORM |
| 13 | Uncovering global-scale risks from commercial chemicals in air | Liu Q; Li L; Zhang X; Saini A; Li W; Hung H; Hao C; Li K; Lee P; Wentzell JJB; Huo C; Li SM; Harner T; Liggio J; | 34912090 CHEMBIOCHEM |
| 14 | Fast oscillations >40 Hz localize the epileptogenic zone: An electrical source imaging study using high-density electroencephalography. | Avigdor T, Abdallah C, von Ellenrieder N, Hedrich T, Rubino A, Lo Russo G, Bernhardt B, Nobili L, Grova C, Frauscher B | 33450578 PERFORM |
| 15 | Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis | Lyubenova A; Neupane D; Levis B; Wu Y; Sun Y; He C; Krishnan A; Bhandari PM; Negeri Z; Imran M; Rice DB; Azar M; Chiovitti MJ; Saadat N; Riehm KE; Boruff JT; Ioannidis JPA; Cuijpers P; Gilbody S; Kloda LA; Patten SB; Shrier I; Ziegelstein RC; Comeau L; Mitchell ND; Tonelli M; Vigod SN; Aceti F; Barnes J; Bavle AD; Beck CT; Bindt C; Boyce PM; Bunevicius A; Chaudron LH; Favez N; Figueiredo B; Garcia-Esteve L; Giardinelli L; Helle N; Howard LM; Kohlhoff J; Kusminskas L; Kozinszky Z; Lelli L; Leonardou AA; Meuti V; Radoš SN; García PN; Pawlby SJ; Quispel C; Robertson-Blackmore E; Rochat TJ; Sharp DJ; Siu BWM; Stein A; Stewart RC; Tadinac M; Tandon SD; Tendais I; Töreki A; Torres-Giménez A; Tran TD; Trevillion K; Turner K; Vega-Dienstmaier JM; Benedetti A; Thombs BD; | 33089942 CONCORDIA |
| 16 | Contactless Capacitive Electrocardiography Using Hybrid Flexible Printed Electrodes. | Lessard-Tremblay M, Weeks J, Morelli L, Cowan G, Gagnon G, Zednik RJ | 32927651 ENCS |
| 17 | The antibacterial activity of p-tert-butylcalix[6]arene and its effect on a membrane model: molecular dynamics and Langmuir film studies. | Wrobel EC, de Lara LS, do Carmo TAS, Castellen P, Lazzarotto M, de Lázaro SR, Camilo A, Caseli L, Schmidt R, DeWolf CE, Wohnrath K | 32124897 CNSR |
| 18 | Dexamethasone-Induced Perturbations in Tissue Metabolomics Revealed by Chemical Isotope Labeling LC-MS analysis | Dahabiyeh LA; Malkawi AK; Wang X; Colak D; Mujamammi AH; Sabi EM; Li L; Dasouki M; Abdel Rahman AM; | 31973046 CHEMBIOCHEM |
| 19 | Computer-Aided Diagnosis System of Alzheimer's Disease Based on Multimodal Fusion: Tissue Quantification Based on the Hybrid Fuzzy-Genetic-Possibilistic Model and Discriminative Classification Based on the SVDD Model. | Lazli L, Boukadoum M, Ait Mohamed O | 31652635 ENCS |
| 20 | Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis | Levis B; McMillan D; Sun Y; He C; Rice DB; Krishnan A; Wu Y; Azar M; Sanchez TA; Chiovitti MJ; Bhandari PM; Neupane D; Saadat N; Riehm KE; Imran M; Boruff JT; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; Patten SB; Shrier I; Ziegelstein RC; Comeau L; Mitchell ND; Tonelli M; Vigod SN; Aceti F; Alvarado R; Alvarado-Esquivel C; Bakare MO; Barnes J; Beck CT; Bindt C; Boyce PM; Bunevicius A; Couto TCE; Chaudron LH; Correa H; de Figueiredo FP; Eapen V; Fernandes M; Figueiredo B; Fisher JRW; Garcia-Esteve L; Giardinelli L; Helle N; Howard LM; Khalifa DS; Kohlhoff J; Kusminskas L; Kozinszky Z; Lelli L; Leonardou AA; Lewis BA; Maes M; Meuti V; Nakic Radoš S; Navarro García P; Nishi D; Okitundu Luwa E-Andjafono D; Robertson-Blackmore E; Rochat TJ; Rowe HJ; Siu BWM; Skalkidou A; Stein A; Stewart RC; Su KP; Sundström-Poromaa I; Tadinac M; Tandon SD; Tendais I; Thiagayson P; Töreki A; Torres-Giménez A; Tran TD; Trevillion K; Turner K; Vega-Dienstmaier JM; Wynter K; Yonkers KA; Benedetti A; Thombs BD; | 31568624 LIBRARY |
| 21 | The first MICCAI challenge on PET tumor segmentation. | Hatt M, Laurent B, Ouahabi A, Fayad H, Tan S, Li L, Lu W, Jaouen V, Tauber C, Czakon J, Drapejkowski F, Dyrka W, Camarasu-Pop S, Cervenansky F, Girard P, Glatard T, Kain M, Yao Y, Barillot C, Kirov A, Visvikis D | 29268169 IMAGING |
| 22 | Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state. | Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, Roofigari-Esfahani N, Rosanelli L, Titorenko VI | 29050207 BIOLOGY |
| 23 | Expedition Cognition: A Review and Prospective of Subterranean Neuroscience With Spaceflight Applications. | Mogilever NB, Zuccarelli L, Burles F, Iaria G, Strapazzon G, Bessone L, Coffey EBJ | 30425628 PSYCHOLOGY |
| 24 | Human Physiology During Exposure to the Cave Environment: A Systematic Review With Implications for Aerospace Medicine. | Zuccarelli L, Galasso L, Turner R, Coffey EJB, Bessone L, Strapazzon G | 31068833 PSYCHOLOGY |
| Title: | Effect of chronic benzodiazepine and benzodiazepine receptor agonist use on sleep architecture and brain oscillations in older adults with chronic insomnia | ||||
| Authors: | Barbaux L, Perrault AA, Cross NE, Weiner OM, Es-Sounni M, Pomares FB, Tarelli L, McCarthy M, Maltezos A, Smith D, Gong K, O', Byrne J, Yue V, Desrosiers C, Clerc D, Andriamampionona F, Lussier D, Gilbert S, Tannenbaum C, Gouin JP, Dang-Vu TT | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40570297/ | ||||
| DOI: | 10.1093/sleep/zsaf168 | ||||
| Publication: | Sleep | ||||
| Keywords: | aging; benzodiazepine; brain oscillations; sleep; | ||||
| PMID: | 40570297 | Category: | Date Added: | 2025-06-26 | |
| Dept Affiliation: |
CSBN
1 Sleep, Cognition and Neuroimaging Lab, Department of Health, Kinesiology and Applied Physiology, School of Health & Center for Studies in Behavioural Neurobiology, Concordia University, Montreal, QC, Canada. 2 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, CIUSSS Centre-Sud-de-l'Ile-de-Montréal, Québec, Canada. 3 Sleep and Circadian Group, Woolcock Institute of Medical Research, Macquarie University, Sydney, NSW, Australia. 4 School of Psychology, University of Sydney, NSW, Australia. 5 Statistics Canada Biobank, Statistics Canada, ON, Canada. 6 Department of Psychology, Université de Montréal, Montreal, QC, Canada. 7 Stress, Interpersonal Relationship and Health Lab, Department of Psychology & Centre for Clinical Research in Health, Concordia University, Quebec, Canada. |
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Description: |
Study objectives: Insomnia in older adults is associated with widespread benzodiazepine (BZD) and benzodiazepine receptor agonist (BZRA) use, despite evidence that chronic use disrupts sleep regulation and cognition. Little is known about BZD/BZRA effects on NREM slow oscillations (SO), spindles and their coupling, which is crucial for memory, in older adults. Our objective was to investigate the effects of chronic BZD/BZRA use on sleep macro-architecture, EEG relative power, SO and spindle characteristics and coupling. Methods: After habituation polysomnography (PSG), second-night data were analyzed from 101 participants (66.05 ± 5.84 years, range: 55-80 years, 73% female) were categorized into three groups: good sleepers (GS, n = 28), individuals with insomnia (INS, n = 26) or individuals with insomnia who chronically use BZD/BZRA (MED, n = 47; diazepam equivalent: 6.1 ± 3.8 mg per use; >3 nights/week). We performed a comprehensive comparison of sleep architecture, EEG relative spectrum, and associated brain oscillatory activities, focusing on SO and spindles, and their temporal coupling. Results: MED showed disrupted sleep architecture with lower N3 and higher N1 duration and spectral activity, and altered sleep-related brain oscillations synchrony, compared to INS and GS. An exploratory interaction model suggested that chronic use of higher doses (mg per use) correlated with more pronounced disruptions in sleep micro-architecture and EEG spectrum. Conclusions: Our results suggest that chronic BZD and BZRA use is associated with poorer sleep quality. Such alteration of sleep regulation - at the macro and micro-architectural levels - may contribute to the reported association between BZD/BZRA use and cognitive impairment in older adults. |
