Keyword search (4,163 papers available)

"Li P" Authored Publications:

Title Authors PubMed ID
1 Associations between brain and cognitive resilience, tau load and extent in Alzheimer's disease Mitchell SW; Chan T; Trudel L; Hosseini SA; Macedo AC; Gonçalves MP; Rahmouni N; Hall BJ; Socualaya KMQ; Therriault J; Servaes S; Bezgin G; Zheng Y; Aumont E; Wang YT; Arias JF; Real APB; Jia WL; Hopewell R; Hsiao C; Soucy JP; Vitali P; Pascoal TA; Rosa-Neto P; 41512332
PERFORM
2 Alzheimer s Imaging Consortium Mitchell SW; Chan T; Trudel L; Hosseini SA; Macedo AC; Gonçalves MP; Rahmouni N; Hall BJ; Socualaya KMQ; Therriault J; Servaes S; Bezgin G; Zheng Y; Aumont E; Wang YT; Arias JF; Real APB; Jia WL; Hopewell R; Hsiao C; Soucy JP; Vitali P; Pascoal TA; Rosa-Neto P; 41433447
PERFORM
3 Trends in missed paediatric preventive primary care visits during the COVID-19 pandemic using routinely collected electronic medical records in Ontario, Canada (2015-2022) Bayoumi I; Mcfadden K; Valkanas H; Tu K; Kalia S; Chen T; Christie CD; Rourke J; Rourke L; Greiver M; Leduc D; Li P; 41290264
CONCORDIA
4 Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular risk factors: the ACTIONcardioRisk protocol Bherer L; Vrinceanu T; Dupuy EG; Gayda M; Vincent T; Magnan PO; Mohammadi H; Gauthier C; Gagnon C; Duchesne S; Erickson KI; Gagnon D; Lesage F; Lupien S; Poirier J; Dubé MP; Thorin É; Juneau M; Breton J; Belleville S; Ferland G; Gaudreau-Majeau F; Blanchette CA; Vitali P; Nigam A; 40625372
PSYCHOLOGY
5 Adaptive finite-time synchronized control of multi-robotic fiber placement system with model uncertainties and disturbances Zhang R; Wang Y; Xie W; Li P; Tan H; Jiang Y; 40461302
ENCS
6 Dynamic and Reprocessable Fluorinated Poly(hindered urea) Network Materials Containing Ionic Liquids to Enhance Triboelectric Performance Nellepalli P; Kim MP; Park J; Noh SM; Ye Z; Jung HW; Ko H; Oh JK; 35385641
CHEMBIOCHEM
7 Dynamic Covalent Polyurethane Network Materials: Synthesis and Self-healability Nellepalli P; Patel T; Oh JK; 34418209
CHEMBIOCHEM
8 Macromolecularly Engineered Thermoreversible Heterogeneous Self-Healable Networks Encapsulating Reactive Multidentate Block Copolymer-Stabilized Carbon Nanotubes Zhang G; Patel T; Nellepalli P; Bhagat S; Hase H; Jazani AM; Salzmann I; Ye Z; Oh JK; 33988899
CHEMBIOCHEM
9 Self-Healable Reprocessable Triboelectric Nanogenerators Fabricated with Vitrimeric Poly(hindered Urea) Networks. Patel T, Kim MP, Park J, Lee TH, Nellepalli P, Noh SM, Jung HW, Ko H, Oh JK 32840992
CHEMBIOCHEM
10 Hypertension Canada's 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children. Rabi DM, McBrien KA, Sapir-Pichhadze R, Nakhla M, Ahmed SB, Dumanski SM, Butalia S, Leung AA, Harris KC, Cloutier L, Zarnke KB, Ruzicka M, Hiremath S, Feldman RD, Tobe SW, Campbell TS, Bacon SL, Nerenberg KA, Dresser GK, Fournier A, Burgess E, Lindsay P, Rabkin SW, Prebtani APH, Grover S, Honos G, Alfonsi JE, Arcand J, Audibert F, Benoit G, Bittman J, Bolli P, Côté AM, Dionne J, Don-Wauchope A, Edwards C, Firoz T, Gabor JY, Gilbert RE, Grégoire JC, Gryn SE, Gupta M, Hannah-Shmouni F, Hegele RA, Herman RJ, H 32389335
HKAP
11 Hypertension Canada's 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension. Leung AA, Nerenberg K, Daskalopoulou SS, McBrien K, Zarnke KB, Dasgupta K, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tobe SW, Ruzicka M, Burns KD, Vallée M, Prasad GV, Lebel M, Feldman RD, Selby P, Pipe A, Schiffrin EL, McFarlane PA, Oh P, Hegele RA, Khara M, Wilson TW, Penner SB, Burgess E, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell NR, Moe GW, Howlett JG, Boulanger JM, Prebtani A, Laroc 27118291
HKAP
12 Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults. Leung AA, Daskalopoulou SS, Dasgupta K, McBrien K, Butalia S, Zarnke KB, Nerenberg K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tran KC, Tobe SW, Ruzicka M, Burns KD, Vallée M, Prasad GVR, Gryn SE, Feldman RD, Selby P, Pipe A, Schiffrin EL, McFarlane PA, Oh P, Hegele RA, Khara M, Wilson TW, Penner SB, Burgess E, Sivapalan P, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell 28449828
HKAP
13 Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Padwal RS, Tran KC, Grover S, Rabkin SW, Moe GW, Howlett JG, Lindsay P, Hill MD, Sharma M, Field T, Wein TH, Shoamanesh A, Dresser GK, Hamet P, Herman RJ, Burgess E, Gryn SE, Grégoire JC, Lewanczuk R, Poirier L, Campbell TS, Feldman RD, Lavoie KL, Tsuyuki RT, Honos G, Prebtani APH, Kline G, Schiffrin EL, Don-Wauchope A, Tobe SW, Gilbert RE, 29731013
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Title:Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular risk factors: the ACTIONcardioRisk protocol
Authors:Bherer LVrinceanu TDupuy EGGayda MVincent TMagnan POMohammadi HGauthier CGagnon CDuchesne SErickson KIGagnon DLesage FLupien SPoirier JDubé MPThorin ÉJuneau MBreton JBelleville SFerland GGaudreau-Majeau FBlanchette CAVitali PNigam A
Link:https://pubmed.ncbi.nlm.nih.gov/40625372/
DOI:10.3389/fnagi.2025.1605128
Publication:Frontiers in aging neuroscience
Keywords:active controlcerebrovascular imagingcognitive preventionexercise trainingmultidomain training
PMID:40625372 Category: Date Added:2025-07-08
Dept Affiliation: PSYCHOLOGY
1 Research Centre and Centre EPIC, Montreal Heart Institute, Montréal, QC, Canada.
2 Department of Medicine, Université de Montréal, Montréal, QC, Canada.
3 Research Centre, Institut Universitaire de Gériatrie de Montréal, Montréal, QC, Canada.
4 Department of Physics, Concordia University, Montreal, QC, Canada.
5 Department of Radiology and nuclear medicine, Laval University, Québec City, QC, Canada.
6 AdventHealth Research Institute, Neuroscience, Orlando, FL, United States.
7 Department of Psychiatry, Université de Montréal, Montréal, QC, Canada.
8 Department of Psychiatry, McGill University, Montreal, QC, Canada.
9 Department of Psychology, Université de Montréal, Montréal, QC, Canada.
10 Department of Nutrition, Université de Montréal, QC, Canada.
11 Department of Neurology, McGill University, Montreal, QC, Canada.

Description:

Background: Lifestyle factors like exercise and cognitive stimulation might help improve cognitive performance in older adults. However, studies investigating this, reported mixed results. Most of the data supporting the benefit of exercise comes from cross-sectional studies, cohort studies, or short intervention studies of 3-6 months with poorly designed control groups. Meta-analyses suggest that longer intervention studies of around 1 year are more likely to show cognitive improvements and changes in brain biomarkers. Moreover, the type and content and optimal dose of the training program that best predict improvement in cognition is still poorly understood. Latest studies suggest that combining cognitive training with exercise training might have an added benefit. Moreover, functional and structural cerebral mechanisms involved are still poorly documented. Finally, few studies have systematically investigated the potential impact that cardiovascular risk factors (CVRF) progression might have on training neurocognitive outcomes.

Methods: 159 seniors over the age of 60 with CVRF and no contraindications to exercise will be assigned to one of the three 1-year training programs: (1) Physical exercise intervention (aerobic and resistance exercises); (2) Multidomain intervention (combined cognitive training with aerobic and resistance exercises); or (3) Active control (stretching and toning exercises). All interventions take place 3 times a week, are supervised and individualized to each participant's profile. Assessments will be administered before, half-way and after the intervention: cognition (primary outcome), cerebral imaging with a focus on cerebrovascular mechanisms (secondary outcomes), and exploratory outcomes (genetic profile, chronic stress biomarkers, metabolic function, inflammation markers, mood, sleep, and diet).

Discussion: The present design uses a 12-month intervention period to maximize the likelihood of identifying the cerebrovascular markers involved in exercise training effects on cognitive performance in individuals with CVRF. Moreover, we measure a series of exploratory outcomes that could also play a role in modulating the effect of the multidomain training on cognition. This will allow an investigation of their potential mediating role on the primary outcomes.

Clinical trial registration: [https://clinicaltrials.gov/] identifier [NCT04962061].





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