Keyword search (4,163 papers available)

"Messina C" Authored Publications:

Title Authors PubMed ID
1 Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C-H Arylation Buonomano C; Patterson S; Ngou JS; Messina C; Taylor S; Bilodeau F; Forgione P; 41900086
CHEMBIOCHEM
2 A Modular and Regioselective Synthesis of Di- and Triarylated Thiophenes: Strategies for Accessing Challenging Isomeric Motifs Messina C; McKibbon K; Wong KS; Prevost P; Petkov V; Forgione P; 41160050
CONCORDIA
3 Diverse Applications of Biomass-Derived 5-Hydroxymethylfurfural and Derivatives as Renewable Starting Materials Chacón-Huete F; Messina C; Cigana B; Forgione P; 35652539
CHEMBIOCHEM
4 Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity Messina C; Ottenwaelder X; Forgione P; 34506149
CHEMBIOCHEM

 

Title:Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity
Authors:Messina COttenwaelder XForgione P
Link:https://pubmed.ncbi.nlm.nih.gov/34506149/
DOI:10.1021/acs.orglett.1c02447
Publication:Organic letters
Keywords:
PMID:34506149 Category: Date Added:2021-09-11
Dept Affiliation: CHEMBIOCHEM
1 Department of Chemistry and Biochemistry, Concordia University, Montreal, Quebec H4B 1R6, Canada.

Description:

Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of individual positions of thiophene sequentially via regioselective halogenations and cross-coupling reactions. The reaction sequence described provides tetra-arylated thiophenes in higher yields than previous routes and employs practical reaction protocols, simple catalytic systems, and short reaction times.





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