Keyword search (4,163 papers available)

"Morin CM" Authored Publications:

Title Authors PubMed ID
1 The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 41688421
SOH
2 The complex association between bedtime screen use and adult sleep health Vézina-Im LA; Morin CM; Chen S; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Robillard R; 40713469
HKAP
3 Efficacy of cognitive behavioral therapy for insomnia and lemborexant medication for different subtypes of chronic insomnia: study protocol for a randomized controlled trial Chen SJ; Ivers H; Dang-Vu TT; Shapiro CM; Carney CE; Robillard R; Morin CM; 40346496
HKAP
4 Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L; 39739397
SOH
5 Trends in nighttime insomnia symptoms in Canada from 2007 to 2021 Chaput JP; Morin CM; Robillard R; Carney CE; Dang-Vu TT; Davidson JR; Tomkinson GR; Lang JJ; 39556998
HKAP
6 Delphi consensus recommendations for the management of chronic insomnia in Canada Morin CM; Khullar A; Robillard R; Desautels A; Mak MSB; Dang-Vu TT; Chow W; Habert J; Lessard S; Alima L; Ayas NT; MacFarlane J; Kendzerska T; Lee EK; Carney CE; 39481275
HKAP
7 Prevalence of insomnia and use of sleep aids among adults in Canada Morin CM; Vézina-Im LA; Chen SJ; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Belleville G; Lorrain D; Horn O; Robillard R; 39369578
HKAP
8 Economic burden of insomnia symptoms in Canada Chaput JP; Janssen I; Sampasa-Kanyinga H; Carney CE; Dang-Vu TT; Davidson JR; Robillard R; Morin CM; 36319579
PERFORM

 

Title:Efficacy of cognitive behavioral therapy for insomnia and lemborexant medication for different subtypes of chronic insomnia: study protocol for a randomized controlled trial
Authors:Chen SJIvers HDang-Vu TTShapiro CMCarney CERobillard RMorin CM
Link:https://pubmed.ncbi.nlm.nih.gov/40346496/
DOI:10.1186/s12888-025-06878-1
Publication:BMC psychiatry
Keywords:Cognitive behavioral therapy for insomniaInsomnia phenotypesPharmacotherapyTreatment
PMID:40346496 Category: Date Added:2025-05-10
Dept Affiliation: HKAP
1 École de Psychologie, Université Laval, 2325 Rue Des Bibliothèques, Québec, Québec, G1V 0A6, Canada.
2 Centre de recherche CERVO/Brain Research Center, 2301 Av. D'Estimauville, Québec, Québec, G1E 1T2, Canada.
3 Li Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
4 Department of Health, Kinesiology and Applied Physiology, Concordia University, 7141 Sherbrooke Street West, Montréal, Québec, H4B 1R6, Canada.
5 Centre de Recherche de L'Institut Universitaire de Gériatrie de Montréal (CRIUGM), CIUSSS du Centre-Sud-de-L'île-de-Montréal, 4565 Queen Mary Road, Montréal, Québec, H3W 1W5, Canada.
6 Medical Sciences, University of Toronto, 399 Bathurst St, MP7, 421, Toronto, Ontario, M5T 2S8, Canada.
7 Department of Psychology, Toronto Metropolitan University, 350 Victoria Street, Toronto, Ontario, M5B 2K3, Canada.
8 School of Psychology, University of Ottawa, 136 J

Description:

Introduction: Insomnia is a prevalent yet under-characterized disorder, particularly regarding the heterogeneity of patients and their associated responses to different treatment modalities. This often leads to suboptimal management. There is a need to consider personalized approaches tailored to the characteristics of insomnia phenotypes with regard to objective evidence of shortened sleep duration (< 6 h). This study will examine whether there is a differential treatment response to cognitive behavioral therapy for insomnia (CBT-I) versus pharmacotherapy (lemborexant) as a function of insomnia phenotypes (i.e., ± 6 h of sleep).

Methods: This study is a three-arm pragmatic randomized clinical trial, which will enroll 90 adults with chronic insomnia disorder and anxiety/depressive symptoms. Eligible participants will be randomized to one of three conditions (1:1:1) involving CBT-I, lemborexant (Dual Orexin Receptor Antagonist) or placebo medication. Treatment outcomes will be assessed at post-treatment and 6-month follow-up. Insomnia symptom severity as measured by the Insomnia Severity Index will serve as the primary outcome for treatment comparisons. Secondary outcomes will include daily sleep/wake variables derived from the Consensus Sleep Diary, subjective measures of fatigue, mood, mental well-being, functional impairments, and sleep-related beliefs and attitudes. In addition, changes in cognitive performance will be examined as an exploratory outcome. Sleep reactivity and arousal level will be evaluated as potential mediators of treatment-related changes in CBT-I and pharmacotherapy.

Discussion: This study will contribute to the development of personalized medicine for managing different insomnia phenotypes and will have implication for knowledge mobilization of sleep research.

Trial registration: ClinicalTrials.gov. Identifier: NCT06779149. Registered on 12 January 2025.





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