BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,164 papers available) |  |
"Postuma RB" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Increased brain cholinergic innervation in isolated REM sleep behaviour disorder from prodromal multiple system atrophy | Wickens RH; Postuma RB; de Villers-Sidani É; Pelletier A; Blinder S; Gagnon JF; Soucy JP; Montplaisir J; Bedard MA; | 37939636 PERFORM |
| 2 | A dataset of multi-contrast unbiased average MRI templates of a Parkinson's disease population | Madge V; Fonov VS; Xiao Y; Zou L; Jackson C; Postuma RB; Dagher A; Fon EA; Collins DL; | 37213552 IMAGING |
| 3 | Insomnia disorder increases the risk of subjective memory decline in middle-aged and older adults: a longitudinal analysis of the Canadian Longitudinal Study on Aging | Zhao JL; Cross N; Yao CW; Carrier J; Postuma RB; Gosselin N; Kakinami L; Dang-Vu TT; | 35877203 PERFORM |
| 4 | Insomnia symptom subtypes and manifestations of prodromal neurodegeneration: a population-based study in the CLSA | Yao CW; Pelletier A; Fereshtehnejad SM; Cross N; Dang-Vu T; Postuma RB; | 34314348 PERFORM |
| 5 | Effects of menopause on sleep quality and sleep disorders: Canadian Longitudinal Study on Aging. | Zolfaghari S, Yao C, Thompson C, Gosselin N, Desautels A, Dang-Vu TT, Postuma RB, Carrier J | 31851117 PERFORM |
| 6 | Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies | Krohn L; Öztürk TN; Vanderperre B; Ouled Amar Bencheikh B; Ruskey JA; Laurent SB; Spiegelman D; Postuma RB; Arnulf I; Hu MTM; Dauvilliers Y; Högl B; Stefani A; Monaca CC; Plazzi G; Antelmi E; Ferini-Strambi L; Heidbreder A; Rudakou U; Cochen De Cock V; Young P; Wolf P; Oliva P; Zhang XK; Greenbaum L; Liong C; Gagnon JF; Desautels A; Hassin-Baer S; Montplaisir JY; Dupré N; Rouleau GA; Fon EA; Trempe JF; Lamoureux G; Alcalay RN; Gan-Or Z; | 31658403 CERMM |
| 7 | Brain cholinergic alterations in idiopathic REM sleep behaviour disorder: a PET imaging study with 18F-FEOBV. | Bedard MA, Aghourian M, Legault-Denis C, Postuma RB, Soucy JP, Gagnon JF, Pelletier A, Montplaisir J | 31078078 PERFORM |
| 8 | Association between insomnia disorder and cognitive function in middle-aged and older adults: a cross-sectional analysis of the Canadian Longitudinal Study on Aging | Cross NE; Carrier J; Postuma RB; Gosselin N; Kakinami L; Thompson C; Chouchou F; Dang-Vu TT; | 31089710 PERFORM |
| Title: | Association between insomnia disorder and cognitive function in middle-aged and older adults: a cross-sectional analysis of the Canadian Longitudinal Study on Aging | ||||
| Authors: | Cross NE, Carrier J, Postuma RB, Gosselin N, Kakinami L, Thompson C, Chouchou F, Dang-Vu TT | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/31089710/ | ||||
| DOI: | 10.1093/sleep/zsz114 | ||||
| Publication: | Sleep | ||||
| Keywords: | CLSA; aging; cognition; cohort; insomnia; | ||||
| PMID: | 31089710 | Category: | Sleep | Date Added: | 2019-05-16 |
| Dept Affiliation: |
PERFORM
1 Institut Universitaire de Geriatrie de Montreal and CRIUGM, CIUSSS du Centre-Sud-de-l'Ile-de-Montreal, Montreal, Canada. 2 PERFORM Centre, Concordia University, Montreal, Canada. 3 Center for Studies in Behavioral Neurobiology, Department of Health, Kinesiology and Applied Physiology, Concordia University, Montreal, Canada. 4 Canadian Sleep and Circadian Network, Montreal, Canada. 5 Center for Advanced Research in Sleep Medicine, Hopital du Sacre- Coeur de Montreal, CIUSSS du Nord-de-l'Ile-de-Montreal, Montreal, Canada. 6 Department of Neurology, McGill University - Montreal General Hospital, Montreal, Canada. 7 Department of Psychology, Universite de Montreal, Montreal, Canada. 8 Department of Mathematics and Statistics, Concordia University. 9 IRISSE Laboratory, UFR SHE, University of La Réunion, Le Tampon, France. |
||||
Description: |
Objectives: This study examined the differences in cognitive function between middle-aged and older adults with insomnia disorder, insomnia symptoms only (ISO) or no insomnia symptoms (NIS), in the context of other health and lifestyle factors. Methods: Twenty-eight thousand four hundred eighty-five participants >45 years completed questionnaires, physical examinations, and neuropsychological testing across domains of processing speed, memory, and executive functions. An eight-question instrument assessed participants' sleep, defining subjects with insomnia symptoms, probable insomnia disorder (PID), or NIS. The associations between these three groups and cognitive performance were examined with linear regression models adjusted for lifestyle and clinical factors. Results: PID was identified in 1,068 participants (3.7% of the sample) while 7,813 (27.5%) experienced ISO. Participants with PID exhibited greater proportions of adverse medical and lifestyle features such as anxiety, depression, and diabetes than both other groups. Analyses adjusting for age, sex, education, as well as medical and lifestyle factors demonstrated that adults with PID exhibited declarative memory deficits (Rey Auditory Verbal Learning Test) compared with ISO or NIS. Adults with insomnia symptoms exhibited better performance on a task of mental flexibility than both other groups. Conclusions: These findings suggest that insomnia disorder in middle-aged and older adults is associated with poorer health outcomes and worse memory performance than adults with insomnia symptoms alone or without any sleep complaints, even after adjustment for comorbidities. The assessment of longitudinal data within this cohort will be critical to understand if insomnia disorder may increase the risk of further cognitive decline. |
