BookR: School of Health Core Facilities Booking
PubMed Publications| Keyword search (4,164 papers available) |  |
"Son S" Authored Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C-H Arylation | Buonomano C; Patterson S; Ngou JS; Messina C; Taylor S; Bilodeau F; Forgione P; | 41900086 CHEMBIOCHEM |
| 2 | Clinical Manifestations | Gagnon C; Montero-Odasso M; Zou G; Speechley MR; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li K; Fraser S; Pieruccini-Faria F; Burhan AM; Berryman N; Lussier M; Son S; Shoemaker JK; Bherer L; | 41447475 CONCORDIA |
| 3 | Public Health | Pieruccini-Faria F; Son S; Liu-Ambrose T; Burhan AM; Almeida QJ; Middleton LE; Li K; Fraser S; Bherer L; Montero-Odasso M; | 41435121 CONCORDIA |
| 4 | Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial | Pieruccini-Faria F; Son S; Zou G; Almeida QJ; Middleton LE; Bray NW; Lussier M; Shoemaker JK; Speechley M; Liu-Ambrose T; Burhan AM; Camicioli R; Li KZH; Fraser S; Berryman N; Bherer L; Montero-Odasso M; | 40966614 SOH |
| 5 | Sequencing of a Dairy Isolate Unlocks em Kluyveromyces marxianus /em as a Host for Lactose Valorization | Thornbury M; Knoops A; Summerby-Murray I; Dhaliwal J; Johnson S; Utomo JC; Joshi J; Narcross L; Remondetto G; Pouliot M; Whiteway M; Martin VJJ; | 40629255 BIOLOGY |
| 6 | Self-Ambivalence Is Indirectly Associated With Obsessive-Compulsive and Eating Disorder Symptoms Through Different Feared Self-Themes | Wilson S; Mesli N; Mehak A; Racine SE; | 40227164 PSYCHOLOGY |
| 7 | Expanding a Behavioral View on Digital Health Access: Drivers and Strategies to Promote Equity | Kepper MM; Fowler LA; Kusters IS; Davis JW; Baqer M; Sagui-Henson S; Xiao Y; Tarfa A; Yi JC; Gibson B; Heron KE; Alberts NM; Burgermaster M; Njie-Carr VP; Klesges LM; | 39088246 PSYCHOLOGY |
| 8 | Feasibility and acceptability of an adapted peer-based walking intervention for adults with moderate-to-severe traumatic brain injury | Quilico EL; Wilkinson S; Duncan LR; Sweet SN; Alarie C; Bédard E; Gheta I; Brodeur CL; Colantonio A; Swaine BR; | 39051571 CONCORDIA |
| 9 | Criminal Code reform of HIV non-disclosure is urgently needed: Social science perspectives on the harms of HIV criminalization in Canada | Hastings C; French M; McClelland A; Mykhalovskiy E; Adam B; Bisaillon L; Bogosavljevic K; Gagnon M; Greene S; Guta A; Hindmarch S; Kaida A; Kilty J; Massaquoi N; Namaste V; O' Byrne P; Orsini M; Patterson S; Sanders C; Symington A; Wilson C; | 38087186 PSYCHOLOGY |
| 10 | Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to anti-fungal compounds | Dumeaux V; Massahi S; Bettauer V; Mottola A; Dukovny A; Khurdia SS; Costa ACBP; Omran RP; Simpson S; Xie JL; Whiteway M; Berman J; Hallett MT; | 37888959 BIOLOGY |
| 11 | Spatial and Temporal Availability of Cloud-free Optical Observations in the Tropics to Monitor Deforestation | Flores-Anderson AI; Cardille J; Azad K; Cherrington E; Zhang Y; Wilson S; | 37607919 ENCS |
| 12 | Effects of Exercise Alone or Combined With Cognitive Training and Vitamin D Supplementation to Improve Cognition in Adults With Mild Cognitive Impairment: A Randomized Clinical Trial | Montero-Odasso M; Zou G; Speechley M; Almeida QJ; Liu-Ambrose T; Middleton LE; Camicioli R; Bray NW; Li KZH; Fraser S; Pieruccini-Faria F; Berryman N; Lussier M; Shoemaker JK; Son S; Bherer L; | 37471089 PERFORM |
| 13 | COVID-19's impact on a community-based physical activity program for adults with moderate-to-severe TBI | Quilico EL; Wilkinson S; Bédard E; Duncan LR; Sweet SN; Swaine BR; Colantonio A; | 37184357 AHSC |
| 14 | Exploring a peer-based physical activity program in the community for adults with moderate-to-severe traumatic brain injury | Quilico E; Sweet S; Duncan L; Wilkinson S; Bonnell K; Alarie C; Swaine B; Colantonio A; | 37157834 AHSC |
| 15 | A metagenomic-based study of two sites from the Barbadian reef system | Simpson S; Bettauer V; Ramachandran A; Kraemer S; Mahon S; Medina M; Vallès Y; Dumeaux V; Vallès H; Walsh D; Hallett MT; | 37009568 BIOLOGY |
| 16 | Participatory co-creation of an adapted physical activity program for adults with moderate-to-severe traumatic brain injury | Quilico E; Wilkinson S; Duncan L; Sweet S; Bédard E; Trudel E; Colantonio A; Swaine B; | 36188895 AHSC |
| 17 | A Deep Learning Approach to Capture the Essence of Candida albicans Morphologies | Bettauer V; Costa ACBP; Omran RP; Massahi S; Kirbizakis E; Simpson S; Dumeaux V; Law C; Whiteway M; Hallett MT; | 35972285 BIOLOGY |
| 18 | Mutations in TRAPPC12 Manifest in Progressive Childhood Encephalopathy and Golgi Dysfunction. | Milev MP, Grout ME, Saint-Dic D, Cheng YH, Glass IA, Hale CJ, Hanna DS, Dorschner MO, Prematilake K, Shaag A, Elpeleg O, Sacher M, Doherty D, Edvardson S | 28777934 BIOLOGY |
| 19 | Parental Nutrition Knowledge Rather Than Nutrition Label Use Is Associated With Adiposity in Children. | Kakinami L, Houle-Johnson S, McGrath JJ | 27373860 PERFORM |
| Title: | Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment-secondary outcomes from the SYNERGIC trial | ||||
| Authors: | Pieruccini-Faria F, Son S, Zou G, Almeida QJ, Middleton LE, Bray NW, Lussier M, Shoemaker JK, Speechley M, Liu-Ambrose T, Burhan AM, Camicioli R, Li KZH, Fraser S, Berryman N, Bherer L, Montero-Odasso M | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40966614/ | ||||
| DOI: | 10.1093/ageing/afaf242 | ||||
| Publication: | Age and ageing | ||||
| Keywords: | Falls; Mild Cognitive Impairment; cognitive; exercises; gait; older people; training; vitamin D; | ||||
| PMID: | 40966614 | Category: | Date Added: | 2025-09-18 | |
| Dept Affiliation: |
SOH
1 Department of Medicine, Division of Geriatric Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada. 2 Parkwood Institute, Gait and Brain Laboratory, London, Ontario, Canada. 3 Western University, Schulich School of Medicine and Dentistry, Department of Epidemiology and Biostatistics, London, Ontario, Canada. 4 Alimentiv Inc., London, Ontario, Canada. 5 Carespace Health and Wellness Neurodegeneration Clinics, Waterloo, Ontario, Canada. 6 Department of Kinesiology and Health Sciences, University of Waterloo, Waterloo, Ontario, Canada. 7 Schlegel-UW Research Institute for Aging, Waterloo, Ontario, Canada. 8 Recovery and Performance Laboratory, Biomedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, Newfoundland and Labrador, Canada. 9 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Montreal, Quebec, Canada. 10 École de Réadaptation, Faculté de Médecine, Université de Montréal, Montreal, Québec, Canada. 11 School of Kinesiology, University of Western Ontario, London, Ontario, Canada. 12 Department of Epidemiology and Biostatistics, and Schulich Interfaculty Program in Public Health, Western University, London, Ontario, Canada. 13 Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada. 14 Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada. 15 Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada. 16 Ontario Shores Centre for Mental Health Sciences, Whitby, Ontario, Canada. 17 Department of Psychiatry, Temerity Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. 18 Department of Medicine and Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada. 19 Department of Psychology, Concordia University, Montréal, Québec, Canada. 20 Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada. 21 Département des Sciences de l'Activité Physique, Université du Québec à Montréal, Montréal, Québec, Canada. 22 Institut national du sport du Québec, Montréal, Québec, Canada. 23 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Québec, Canada. 24 Centre de Recherche, Institut de Cardiologie de Montréal, Montréal, Québec, Canada. 25 Département de Médecine, Université de Montréal, Montréal, Québec, Canada. |
||||
Description: |
Background: Older adults with mild cognitive impairment (MCI) have a higher risk of gait impairments and falls; yet, the effects of multimodal interventions, including combinations of exercises with cognitive training, on improving their mobility remain unclear. Objectives: To investigate the synergistic effects of aerobic-resistance exercise combined with cognitive training, with or without vitamin D supplementation, on gait performance and falls risk in older adults with MCI. Methods: The effect of 20 weeks of aerobic-resistance exercise, cognitive training, and Vitamin D supplementation (10 000 IU 3×/week) on gait and falls in older adults with MCI was evaluated in the SYNERGIC trial, using a fractional factorial design. Assessments were conducted at baseline, 6-month endpoint (after intervention) and 12-month endpoint (follow-up). Eligible participants were between the ages of 65 and 84 years with MCI enrolled from 19 September 2016 to 7 April 2020. Main outcomes of interest for gait performance were gait speed and gait variability changes, whilst for falls were incidental falls and incidental injurious falls. Results: Amongst 161 participants, the four exercise-based arms improved gait speed (+7.5 cm/s, P < .001) and reduced falls (incidence rate ratios (IRR) = 0.65, 95% confidence interval (CI): 0.32-1.42, P = .25) and injurious falls (IRR = 0.38, 95% CI: 0.15-1.05, P = .05) at 6-month endpoint. Falls reduction reached statistical significance (IRR = 0.28, 95% CI: 0.13-0.64, P = .002) at 12-month endpoint. Exercises combined with cognitive training showed the greatest gains in gait speed at 6-month endpoint (P < .001) and in reducing falls at 12-month endpoint (IRR = 0.24, 95% CI: 0.05-0.77, P = .02) compared to the control. Vitamin D did not enhance outcomes and increased gait variability, a marker of instability. Conclusion: Aerobic-resistance exercise combined with sequential computerised cognitive training improved gait performance at 6 months and decreased the risk of falls and injuries at 12 months in older adults with MCI. The addition of vitamin D did not produce benefits. |
