Keyword search (4,163 papers available)

"Titorenko VI" Authored Publications:

Title Authors PubMed ID
1 Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast Leonov A; Feldman R; Piano A; Arlia-Ciommo A; Junio JAB; Orfanos E; Tafakori T; Lutchman V; Mohammad K; Elsaser S; Orfali S; Rajen H; Titorenko VI; 35937500
BIOLOGY
2 Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast Mohammad K; Orfanos E; Titorenko VI; 34853658
BIOLOGY
3 Caloric restriction creates a metabolic pattern of chronological aging delay that in budding yeast differs from the metabolic design established by two other geroprotectors Mohammad K; Titorenko VI; 33868583
BIOLOGY
4 Quantitative Metabolomics of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry Mohammad K; Jiang H; Titorenko VI; 33491678
BIOLOGY
5 Mechanisms that Link Chronological Aging to Cellular Quiescence in Budding Yeast. Mohammad K, Baratang Junio JA, Tafakori T, Orfanos E, Titorenko VI 32630624
BIOLOGY
6 Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast. Dakik P, Rodriguez MEL, Junio JAB, Mitrofanova D, Medkour Y, Tafakori T, Taifour T, Lutchman V, Samson E, Arlia-Ciommo A, Rukundo B, Simard É, Titorenko VI 32577164
BIOLOGY
7 Quantitative Analysis of the Cellular Lipidome of Saccharomyces Cerevisiae Using Liquid Chromatography Coupled with Tandem Mass Spectrometry Mohammad K; Jiang H; Hossain MI; Titorenko VI; 32202524
BIOLOGY
8 Mechanisms by which PE21, an extract from the white willow Salix alba, delays chronological aging in budding yeast. Medkour Y, Mohammad K, Arlia-Ciommo A, Svistkova V, Dakik P, Mitrofanova D, Rodriguez MEL, Junio JAB, Taifour T, Escudero P, Goltsios FF, Soodbakhsh S, Maalaoui H, Simard É, Titorenko VI 31645900
BIOLOGY
9 Aging and Age-related Disorders: From Molecular Mechanisms to Therapies. Titorenko VI 31277345
BIOLOGY
10 Metabolomic and lipidomic analyses of chronologically aging yeast. Richard VR, Bourque SD, Titorenko VI 25213255
BIOLOGY
11 Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome. Beach A, Richard VR, Bourque S, Boukh-Viner T, Kyryakov P, Gomez-Perez A, Arlia-Ciommo A, Feldman R, Leonov A, Piano A, Svistkova V, Titorenko VI 25839782
MASSSPEC
12 Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK). Draz H, Goldberg AA, Titorenko VI, Tomlinson Guns ES, Safe SH, Sanderson JT 28923415
BIOLOGY
13 Lipid metabolism and transport define longevity of the yeast Saccharomyces cerevisiae. Mitrofanova D, Dakik P, McAuley M, Medkour Y, Mohammad K, Titorenko VI 28930594
BIOLOGY
14 Caloric restriction extends yeast chronological lifespan via a mechanism linking cellular aging to cell cycle regulation, maintenance of a quiescent state, entry into a non-quiescent state and survival in the non-quiescent state. Leonov A, Feldman R, Piano A, Arlia-Ciommo A, Lutchman V, Ahmadi M, Elsaser S, Fakim H, Heshmati-Moghaddam M, Hussain A, Orfali S, Rajen H, Roofigari-Esfahani N, Rosanelli L, Titorenko VI 29050207
BIOLOGY
15 Some Metabolites Act as Second Messengers in Yeast Chronological Aging. Mohammad K, Dakik P, Medkour Y, McAuley M, Mitrofanova D, Titorenko VI 29543708
BIOLOGY
16 Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die. Mohammad K, Dakik P, Medkour Y, McAuley M, Mitrofanova D, Titorenko VI 29636840
BIOLOGY
17 Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death. Arlia-Ciommo A, Leonov A, Beach A, Richard VR, Bourque SD, Burstein MT, Kyryakov P, Gomez-Perez A, Koupaki O, Feldman R, Titorenko VI 29662634
BIOLOGY
18 Yeast chronological aging is linked to cell cycle regulation. Mohammad K, Titorenko VI 29895227
BIOLOGY
19 Molecular and Cellular Mechanisms of Aging and Age-related Disorders. Titorenko VI 30011889
BIOLOGY
20 Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions. Arlia-Ciommo A, Leonov A, Mohammad K, Beach A, Richard VR, Bourque SD, Burstein MT, Goldberg AA, Kyryakov P, Gomez-Perez A, Koupaki O, Titorenko VI 30405886
BIOLOGY
21 Pairwise combinations of chemical compounds that delay yeast chronological aging through different signaling pathways display synergistic effects on the extent of aging delay. Dakik P, McAuley M, Chancharoen M, Mitrofanova D, Lozano Rodriguez ME, Baratang Junio JA, Lutchman V, Cortes B, Simard É, Titorenko VI 30719227
BIOLOGY
22 Quiescence Entry, Maintenance, and Exit in Adult Stem Cells. Mohammad K, Dakik P, Medkour Y, Mitrofanova D, Titorenko VI 31052375
BIOLOGY
23 Mechanisms Through Which Some Mitochondria-Generated Metabolites Act as Second Messengers That Are Essential Contributors to the Aging Process in Eukaryotes Across Phyla. Dakik P, Medkour Y, Mohammad K, Titorenko VI 31057428
BIOLOGY

 

Title:Metabolomic and lipidomic analyses of chronologically aging yeast.
Authors:Richard VRBourque SDTitorenko VI
Link:https://www.ncbi.nlm.nih.gov/pubmed/25213255?dopt=Abstract
DOI:10.1007/978-1-4939-1363-3_21
Publication:Methods in molecular biology (Clifton, N.J.)
Keywords:
PMID:25213255 Category:Methods Mol Biol Date Added:2019-06-20
Dept Affiliation: BIOLOGY
1 Department of Biology, Concordia University, 7141 Sherbrooke Street, West, SP Building, Montreal, QC, Canada, H4B 1R6.

Description:

Metabolomic and lipidomic analyses of chronologically aging yeast.

Methods Mol Biol. 2014;1205:359-73

Authors: Richard VR, Bourque SD, Titorenko VI

Abstract

Metabolomic and lipidomic analyses of yeast cells provide comprehensive empirical datasets for unveiling mechanisms underlying complex biological processes. In this chapter, we describe detailed protocols for using such analyses to study the age-related dynamics of changes in intracellular and extracellular levels of various metabolites and membrane lipids in chronologically aging yeast. The protocols for the following high-throughput analyses are described: (1) microanalytic biochemical assays for monitoring intracellular concentrations of trehalose and glycogen; (2) gas chromatographic quantitative assessment of extracellular concentrations of ethanol and acetic acid; and (3) mass spectrometric identification and quantitation of the entire complement of cellular lipids. These protocols are applicable to the exploration of the metabolic patterns associated not only with aging but also with many other vital processes in yeast. The described here methodology complements the powerful genetic approaches available for mechanistic studies of fundamental aspects of yeast biology.

PMID: 25213255 [PubMed - indexed for MEDLINE]





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