PERFORM Publications

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Title		Authors	PubMed ID
1	Differential role of oxytocin and vasopressin in the conditioned ejaculatory preference of the male rat.	Ménard S, Gelez H, Girard-Bériault F, Coria-Avila G, Pfaus JG	31194998 PSYCHOLOGY
2	Corrigendum to "Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial" Physiology & Behavior, Volume 191, 1 July 2018, Pages 138-145.	Goldfield GS, Kenny GP, Prud'homme D, Holcik M, Alberga AS, Fahnestock M, Cameron JD, Doucette S, Hadjiyannakis S, Tulloch H, Tremblay MS, Walsh J, Guerin E, Gunnell KE, D'Angiulli A, Sigal RJ	30428994 PSYCHOLOGY
3	Infusions of ascorbic acid into the medial preoptic area facilitate appetitive sexual behavior in the female rat.	Graham MD, Pfaus JG	24064109 PSYCHOLOGY
4	Modulatory effect of 17-β estradiol on performance of ovariectomized rats on the Shock-Probe test.	Gervais NJ, Jacob S, Brake WG, Mumby DG	24768650 PSYCHOLOGY
5	Conditioned mate-guarding behavior in the female rat.	Holley A, Shalev S, Bellevue S, Pfaus JG	24768651 PSYCHOLOGY
6	The role of oxytocin and vasopressin in conditioned mate guarding behavior in the female rat.	Holley A, Bellevue S, Vosberg D, Wenzel K, Roorda S, Pfaus JG	25724299 PSYCHOLOGY
7	The effects of extrinsic stress on somatic markers and behavior are dependent on animal housing conditions.	Huzard D, Mumby DG, Sandi C, Poirier GL, van der Kooij MA	26220463 PSYCHOLOGY
8	Inhibition of lysine-specific demethylase enzyme disrupts sexually conditioned mate guarding in the female rat.	Holley A, Joulakian L, Wenzel K, Roorda S, Gonzalez B, Sparks L, Pfaus JG	30138634 PSYCHOLOGY

Title:	Infusions of ascorbic acid into the medial preoptic area facilitate appetitive sexual behavior in the female rat.
Authors:	Graham MD, Pfaus JG
Link:	https://www.ncbi.nlm.nih.gov/pubmed/24064109?dopt=Abstract
Publication:
Keywords:
PMID:	24064109	Category:	Physiol Behav	Date Added:	2019-05-31
Dept Affiliation:	PSYCHOLOGY 1 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, QC H4B 1R6, Canada.

Description:

Infusions of ascorbic acid into the medial preoptic area facilitate appetitive sexual behavior in the female rat.

Physiol Behav. 2013 Oct 02;122:140-6

Authors: Graham MD, Pfaus JG

Abstract

Ascorbic acid (AA), also known as Vitamin C, enhances dopamine (DA) transmission in mesolimbic and nigrostriatal terminals and augments DA-mediated behaviors. It is not yet known whether AA has a similar influence in other DA terminals, in particular terminals of the incertohypothalamic system that modulate the function of the medial preoptic area (mPOA). In female rats, DA in the mPOA plays a critical role in the generation of appetitive sexual responses, notably solicitations, hops, and darts, and we have shown previously that the role of DA in this region on female sexual behavior changes depending on the hormonal profile of the female. Since AA has often been used as a vehicle control in the examination of rat sexual behavior, the present study examined the effect of infusions of AA to the mPOA of sexual experienced ovariectomized rats under two hormonal conditions: partially-primed with estradiol benzoate (EB) alone or fully-primed with EB and progesterone. Relative to saline baselines, females under both hormonal conditions displayed a significant increase in appetitive sexual behaviors following infusions of AA. No difference in lordosis behavior was observed following AA infusions relative to saline baselines. We suggest that the mechanism by which AA infusions to the mPOA increase appetitive sexual behaviors in female rats may be through dose-dependent DA receptor interactions, possibly through both presynaptic release mechanisms and postsynaptic DA D1-related messenger systems.

PMID: 24064109 [PubMed - indexed for MEDLINE]

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