Keyword search (4,163 papers available)

"Arterial stiffness" Keyword-tagged Publications:

Title Authors PubMed ID
1 A Cross-Sectional Study on the Impact of Arterial Stiffness on the Corpus Callosum, a Key White Matter Tract Implicated in Alzheimer's Disease Badji A; de la Colina AN; Boshkovski T; Sabra D; Karakuzu A; Robitaille-Grou MC; Gros C; Joubert S; Bherer L; Lamarre-Cliche M; Stikov N; Gauthier CJ; Cohen-Adad J; Girouard H; 32741837
PERFORM
2 Arterial stiffness and brain integrity: A review of MRI findings. Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ 31063866
PERFORM

 

Title:Arterial stiffness and brain integrity: A review of MRI findings.
Authors:Badji A,  Sabra D,  Bherer L,  Cohen-Adad J,  Girouard H,  Gauthier CJ
Link:https://www.ncbi.nlm.nih.gov/pubmed/31063866?dopt=Abstract
DOI:10.1016/j.arr.2019.05.001
Publication:Ageing research reviews
Keywords:Aging;  Arterial spin labell;  Arterial stiffness;  Diffusion;  Magnetic resonance imaging;  Pulse wave velocity;  White matter;  ing; 
PMID:31063866 Category:Ageing Res Rev Date Added:2019-06-04
Dept Affiliation: PERFORM
1 NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montréal, QC, Canada; Neuroimaging Functional Unit (UNF), Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, QC, Canada; Department of Neurosciences, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
2 Neuroimaging Functional Unit (UNF), Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, QC, Canada; Department of Biomedical Science, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
3 Neuroimaging Functional Unit (UNF), Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, QC, Canada; Research Center, Montreal Heart Institute, Montréal, QC, Canada; Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
4 Neuroimaging Functional Unit (UNF), Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, QC, Canada; Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
5 Physics Department, Concordia University, Montréal, QC, Canada; PERFORM Centre, Concordia University, Montréal, QC, Canada; Research Center, Montreal Heart Institute, Montréal, QC, Canada. Electronic address: claudine.gauthier@concordia.ca.

Description:

Arterial stiffness and brain integrity: A review of MRI findings.

Ageing Res Rev. 2019 May 04;53:100907

Authors: Badji A, Sabra D, Bherer L, Cohen-Adad J, Girouard H, Gauthier CJ

Abstract

BACKGROUND: Given the increasing incidence of vascular diseases and dementia, a better understanding of the cerebrovascular changes induced by arterial stiffness is important for early identification of white and gray matter abnormalities that might antedate the appearance of clinical cognitive symptoms. Here, we review the evidence from neuroimaging demonstrating the impact of arterial stiffness on the aging brain.

METHOD: This review presents findings from recent studies examining the association between arterial stiffness, cognitive function, cerebral hypoperfusion, and markers of neuronal fiber integrity using a variety of MRI techniques.

RESULTS: Overall, changes associated with arterial stiffness indicates that the corpus callosum, the internal capsule and the corona radiata may be the most vulnerable regions to microvascular damage. In addition, the microstructural integrity of these regions appears to be associated with cognitive performance. Changes in gray matter structure have also been found to be associated with arterial stiffness and are present as early as the 5th decade. Moreover, low cerebral perfusion has been associated with arterial stiffness as well as lower cognitive performance in age-sensitive tasks such as executive function.

CONCLUSION: Considering the established relationship between arterial stiffness, brain and cognition, this review highlights the need for future studies of brain structure and function in aging to implement measurements of arterial stiffness in parallel with quantitative imaging.

PMID: 31063866 [PubMed - as supplied by publisher]




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