| Keyword search (4,164 papers available) | ![]() |
"Cognition" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Individual differences in empathy-related responses in early childhood: A person-centred approach | Bullinger J; Christner N; Urian R; Kellermann CM; Beaulieu S; Steinbeis N; Dunfield KA; Paulus M; | 41888065 PSYCHOLOGY |
| 2 | Nightly variations in sleep quality and next-day cognitive performance: an in-home study in healthy older adults | Brooks M; El Chami R; Jourde HR; Savard MA; Coffey EBJ; | 41878310 PSYCHOLOGY |
| 3 | Intra-individual variability in cognitive performance predicts falls in older adults with chronic stroke | Dimri V; Davis JC; Boa Sorte Silva NC; Balbim GM; Eng JJ; Liu-Ambrose T; | 41474479 HKAP |
| 4 | Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition | Potvin-Jutras Z; Tremblay PL; Mohammadi H; Villeneuve S; Spreng RN; Gauthier CJ; | 41353310 SOH |
| 5 | Effects of cognitive-behavioral therapy for insomnia during sedative-hypnotics withdrawal on sleep and cognition in older adults | Barbaux L; Cross NE; Perrault AA; Es-Sounni M; Desrosiers C; Clerc D; Andriamampionona F; Lussier D; Tannenbaum C; Guimond A; Grenier S; Gouin JP; Dang-Vu TT; | 41092866 SOH |
| 6 | The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond | Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterbe | 41020412 SOH |
| 7 | The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond | Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterberg H; S | 40778177 PSYCHOLOGY |
| 8 | Statistical or Embodied? Comparing Colorseeing, Colorblind, Painters, and Large Language Models in Their Processing of Color Metaphors | Nadler EO; Guilbeault D; Ringold SM; Williamson TR; Bellemare-Pepin A; Com?a IM; Jerbi K; Narayanan S; Aziz-Zadeh L; | 40621800 PSYCHOLOGY |
| 9 | Connected speech profiles in mild cognitive impairment reflect global cognition | Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM; | 40232260 PSYCHOLOGY |
| 10 | Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease | Páez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbé F; Dang-Vu TT; Ripoll GP; | 39878233 CONCORDIA |
| 11 | Ingestion of polyethylene microplastics impacts cichlid behaviour despite having low retention time | Felismino MEL; Chevallier Rufigny S; Gonzalez-Fleurant SE; Brown GE; | 39862685 BIOLOGY |
| 12 | In Shift and In Variance: Assessing the Robustness of HAR Deep Learning Models Against Variability | Khaked AA; Oishi N; Roggen D; Lago P; | 39860799 ENCS |
| 13 | Infants' Social Evaluation of Helpers and Hinderers: A Large-Scale, Multi-Lab, Coordinated Replication Study | Lucca K; Yuen F; Wang Y; Alessandroni N; Allison O; Alvarez M; Axelsson EL; Baumer J; Baumgartner HA; Bertels J; Bhavsar M; Byers-Heinlein K; Capelier-Mourguy A; Chijiiwa H; Chin CS; Christner N; Cirelli LK; Corbit J; Daum MM; Doan T; Dresel M; Exner A; Fei W; Forbes SH; Franchin L; Frank MC; Geraci A; Giraud M; Gornik ME; Wiesmann CG; Grossmann T; Hadley IM; Havron N; Henderson AME; Matzner EH; Immel BA; Jankiewicz G; Jedryczka W; Kanakogi Y; Kominsky JF; Lew-Williams C; Liberman Z; Liu L; Liu Y; Loeffler MT; Martin A; Mayor J; Meng X; Misiak M; Moreau D; Nencheva ML; Oña LS; Otálora Y; Paulus M; Pepe B; Pickron CB; Powell LJ; Proft M; Quinn AA; Rakoczy H; Reschke PJ; Roth-Hanania R; Rothmaler K; Schlegelmilch K; Schlingloff-Nemecz L; Schmuckler MA; Schuwerk T; Seehagen S; Sen HH; Shainy MR; Silvestri V; Soderstrom M; Sommerville J; Song HJ; Sorokowski P; Stutz SE; Su Y; Taborda-Osorio H; Tan AWM; Tatone D; Taylor-Partridge T; Tsang CKA; Urbanek A; Uzefovsky F; Visser I; Wertz AE; Williams M; Wolsey K; Wong TT; Woodward AM; Wu Y; Zeng Z; Zimmer L; Hamlin JK; | 39600132 PSYCHOLOGY |
| 14 | Effects of Cognition-based and Affect-based Trust Attitudes on Trust Intentions | Gill H; Vreeker-Williamson E; Hing LS; Cassidy SA; Boies K; | 39507389 PSYCHOLOGY |
| 15 | EEG-based study of design creativity: a review on research design, experiments, and analysis | Zangeneh Soroush M; Zeng Y; | 39148896 ENCS |
| 16 | An Ecological Approach to Conceptual Thinking in Material Engagement | Alessandroni N; Malafouris L; Gallagher S; | 39118997 CONCORDIA |
| 17 | Approaches to studying emotion using physiological responses to spoken narratives: A scoping review | Savard MA; Merlo R; Samithamby A; Paas A; Coffey EBJ; | 38961524 PSYCHOLOGY |
| 18 | Exposure to humans and task difficulty levels affect wild raccoons (Procyon lotor) learning | Lazure L; Weladji RB; | 38912327 BIOLOGY |
| 19 | Translating the Interplay of Cognition and Physical Performance in COPD and Interstitial Lung Disease: Meeting Report and Literature Review | Rozenberg D; Reid WD; Camp P; Campos JL; Dechman G; Davenport PW; Egan H; Fisher JH; Guenette JA; Gold D; Goldstein RS; Goodridge D; Janaudis-Ferreira T; Kaplan AG; Langer D; Marciniuk DD; Moore B; Orchanian-Cheff A; Otoo-Appiah J; Pepin V; Rassam P; Rotenberg S; Ryerson C; Spruit MA; Stanbrook MB; Stickland MK; Tom J; Wentlandt K; | 38901488 HKAP |
| 20 | The effects of competition and implicit power motive on men's testosterone, emotion recognition, and aggression | Vongas JG; Al Hajj R; | 28455183 JMSB |
| 21 | Exploring the challenges of avoiding collisions with virtual pedestrians using a dual-task paradigm in individuals with chronic moderate to severe traumatic brain injury | de Aquino Costa Sousa T; Gagnon IJ; Li KZH; McFadyen BJ; Lamontagne A; | 38755606 PERFORM |
| 22 | A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures | Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Yeo BTT; | 38659875 HKAP |
| 23 | A multidimensional investigation of sleep and biopsychosocialprofiles with associated neural signatures | Perrault AA; Kebets V; Kuek NMY; Cross NE; Tesfaye R; Pomares FB; Li J; Chee MWL; Dang-Vu TT; Thomas Yeo BT; | 38559143 HKAP |
| 24 | Loosely controlled experimental EEG datasets for higher-order cognitions in design and creativity tasks | Zangeneh Soroush M; Zhao M; Jia W; Zeng Y; | 38152489 ENCS |
| 25 | Winter's Topography, Law, and the Colonial Legal Imaginary in British Columbia | Matthew P Unger | 37885918 CONCORDIA |
| 26 | The effects of acute exercise and a nap on heart rate variability and memory in young sedentary adults | Mograss M; Frimpong E; Vilcourt F; Chouchou F; Zvionow T; Dang-Vu TT; | 37855092 PERFORM |
| 27 | Age- and sex-specific associations between obstructive sleep apnea risk and cognitive decline in middle-aged and older adults: A 3-year longitudinal analysis of the Canadian longitudinal study on aging | Julie Legault | 37832163 HKAP |
| 28 | Does social connection mediate the association between neuroticism and cognition? Cross-sectional analysis of the Canadian Longitudinal Study on Aging | Bethell J; Andrew MK; Hothi S; Mick P; Morgan D; O' Connell ME; Phillips NA; Stewart S; Walker JD; Wittich W; McGilton KS; | 37667914 CRDH |
| 29 | A Cluster Analysis of Oral and Cognitive Health Indicators: An Exploratory Study on Cholinergic Activity as the Link | Rohani K; Nicolau B; Madathil S; Booij L; Jafarpour D; Haricharan PB; Feine J; Alchini R; Tamimi F; de Souza R; | 37608643 PSYCHOLOGY |
| 30 | Invariant Pattern Recognition with Log-Polar Transform and Dual-Tree Complex Wavelet-Fourier Features | Chen G; Krzyzak A; | 37112182 ENCS |
| 31 | Understanding the impact of radical changes in diet and the gut microbiota on brain function and structure: rationale and design of the EMBRACE study | Ben-Porat T; Alberga A; Audet MC; Belleville S; Cohen TR; Garneau PY; Lavoie KL; Marion P; Mellah S; Pescarus R; Rahme E; Santosa S; Studer AS; Vuckovic D; Woods R; Yousefi R; Bacon SL; | 37088645 PERFORM |
| 32 | Helpers or halos: examining the evaluative mechanisms underlying selective prosociality | Dunfield KA; Isler L; Chang XM; Terrizzi B; Beier J; | 37035290 PSYCHOLOGY |
| 33 | Examining the influence of shyness on children's helping and comforting behaviour | Karasewich TA; Hines C; Pinheiro SGV; Buchenrieder N; Dunfield KA; Kuhlmeier VA; | 36923150 PSYCHOLOGY |
| 34 | Human Activity Recognition with an HMM-Based Generative Model | Manouchehri N; Bouguila N; | 36772428 ENCS |
| 35 | Always Saying the Wrong Thing: Negative Beliefs About Losing Control Cause Symptoms of Social Anxiety | Kelly-Turner K; Radomsky AS; | 36117751 PSYCHOLOGY |
| 36 | The fear of losing control | Adam S Radomsky | 36113905 PSYCHOLOGY |
| 37 | Insomnia disorder increases the risk of subjective memory decline in middle-aged and older adults: a longitudinal analysis of the Canadian Longitudinal Study on Aging | Zhao JL; Cross N; Yao CW; Carrier J; Postuma RB; Gosselin N; Kakinami L; Dang-Vu TT; | 35877203 PERFORM |
| 38 | Specificity of Affective Responses in Misophonia Depends on Trigger Identification | Savard MA; Sares AG; Coffey EBJ; Deroche MLD; | 35692416 PSYCHOLOGY |
| 39 | Effects of cognitive behavioral therapy for insomnia on subjective and objective measures of sleep and cognition | Perrault AA; Pomares FB; Smith D; Cross NE; Gong K; Maltezos A; McCarthy M; Madigan E; Tarelli L; McGrath JJ; Savard J; Schwartz S; Gouin JP; Dang-Vu TT; | 35691208 PERFORM |
| 40 | Association between risk of obstructive sleep apnea, inflammation and cognition after 45 years old in the Canadian Longitudinal Study on Aging | Cynthia Thompson | 35245788 HKAP |
| 41 | Neuropsychological deficits in patients with cognitive complaints after COVID-19 | García-Sánchez C; Calabria M; Grunden N; Pons C; Arroyo JA; Gómez-Anson B; Lleó A; Alcolea D; Belvís R; Morollón N; Mur I; Pomar V; Domingo P; | 35137561 PSYCHOLOGY |
| 42 | Disturbance cues function as a background risk cue but not as an associative learning cue in tadpoles | Rivera-Hernández IAE; Crane AL; Pollock MS; Ferrari MCO; | 35099624 BIOLOGY |
| 43 | Entropy-Based Variational Scheme with Component Splitting for the Efficient Learning of Gamma Mixtures | Bourouis S; Pawar Y; Bouguila N; | 35009726 ENCS |
| 44 | Assessment of the Relationship Between Executive Function and Cardiorespiratory Fitness in Healthy Older Adults | Predovan D; Berryman N; Lussier M; Comte F; Vu TTM; Villalpando JM; Bherer L; | 34803824 PERFORM |
| 45 | Human Activity Recognition: A Comparative Study to Assess the Contribution Level of Accelerometer, ECG, and PPG Signals | Afzali Arani MS; Costa DE; Shihab E; | 34770303 ENCS |
| 46 | Normal cognition in Parkinson's disease may involve hippocampal cholinergic compensation: An exploratory PET imaging study with [(18)F]-FEOBV | Legault-Denis C; Aghourian M; Soucy JP; Rosa-Neto P; Dagher A; Aumont E; Wickens R; Bedard MA; | 34628195 PERFORM |
| 47 | Persuasive Features of Scientific Explanations: Explanatory Schemata of Physical and Psychosocial Phenomena | Jordan Richard Schoenherr | 34552522 PSYCHOLOGY |
| 48 | Complementary variable- and person-centered approaches to the dimensionality of burnout among fire station workers | Sandrin E; Morin AJS; Fernet C; Gillet N; | 34314264 CONCORDIA |
| 49 | Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study. | Pieruccini-Faria F, Black SE, Masellis M, Smith EE, Almeida QJ, Li KZH, Bherer L, Camicioli R, Montero-Odasso M | 33590967 PSYCHOLOGY |
| 50 | On the Impact of Biceps Muscle Fatigue in Human Activity Recognition. | Elshafei M, Costa DE, Shihab E | 33557239 ENCS |
| 51 | Towards Detecting Biceps Muscle Fatigue in Gym Activity Using Wearables. | Elshafei M, Shihab E | 33498702 ENCS |
| 52 | A Benchmark of Data Stream Classification for Human Activity Recognition on Connected Objects. | Khannouz M; Glatard T; | 33202905 ENCS |
| 53 | Theory of mind development: State of the science and future directions. | Poulin-Dubois D | 32859285 PSYCHOLOGY |
| 54 | Hoping for more: How cognitive science has and hasn't been helpful to the OCD clinician. | Ouimet AJ, Ashbaugh AR, Radomsky AS | 29673581 PSYCHOLOGY |
| 55 | A Go/No-go delayed nonmatching-to-sample procedure to measure object-recognition memory in rats. | Cole E, Chad M, Moman V, Mumby DG | 32533993 PSYCHOLOGY |
| 56 | Exercising before a nap benefits memory better than napping or exercising alone. | Mograss M, Crosetta M, Abi-Jaoude J, Frolova E, Robertson E, Pepin V, Dang-Vu TT | 32236442 PERFORM |
| 57 | Effects of perirhinal cortex and hippocampal lesions on rats' performance on two object-recognition tasks. | Cole E, Ziadé J, Simundic A, Mumby DG | 31877339 PSYCHOLOGY |
| 58 | A Quantitative Comparison of Overlapping and Non-Overlapping Sliding Windows for Human Activity Recognition Using Inertial Sensors. | Dehghani A, Sarbishei O, Glatard T, Shihab E | 31752158 ENCS |
| 59 | Knowing who knows: Metacognitive and causal learning abilities guide infants' selective social learning. | Kuzyk O, Grossman S, Poulin-Dubois D | 31519037 CONCORDIA |
| 60 | SYNERGIC TRIAL (SYNchronizing Exercises, Remedies in Gait and Cognition) a multi-Centre randomized controlled double blind trial to improve gait and cognition in mild cognitive impairment. | Montero-Odasso M, Almeida QJ, Burhan AM, Camicioli R, Doyon J, Fraser S, Li K, Liu-Ambrose T, Middleton L, Muir-Hunter S, McIlroy W, Morais JA, Pieruccini-Faria F, Shoemaker K, Speechley M, Vasudev A, Zou GY, Berryman N, Lussier M, Vanderhaeghe L, Bherer L | 29661156 PERFORM |
| 61 | Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA). | Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J, Canadian Gait and Cognition Network | 30101279 PERFORM |
| 62 | Sleep deprivation impairs inhibitory control during wakefulness in adult sleepwalkers. | Labelle MA, Dang-Vu TT, Petit D, Desautels A, Montplaisir J, Zadra A | 26087833 PERFORM |
| 63 | Association between insomnia disorder and cognitive function in middle-aged and older adults: a cross-sectional analysis of the Canadian Longitudinal Study on Aging | Cross NE; Carrier J; Postuma RB; Gosselin N; Kakinami L; Thompson C; Chouchou F; Dang-Vu TT; | 31089710 PERFORM |
| 64 | Gross Motor Skills Training Leads to Increased Brain-Derived Neurotrophic Factor Levels in Healthy Older Adults: A Pilot Study. | Grégoire CA, Berryman N, St-Onge F, Vu TTM, Bosquet L, Arbour N, Bherer L | 31031639 PERFORM |
| 65 | Developmental Changes in Learning: Computational Mechanisms and Social Influences. | Bolenz F, Reiter AMF, Eppinger B | 29250006 PERFORM |
| 66 | The effects of exercise on cognition and gait in Parkinson's disease: A scoping review. | Intzandt B, Beck EN, Silveira CRA | 30291852 PERFORM |
| 67 | Cognitive Involvement in Balance, Gait and Dual-Tasking in Aging: A Focused Review From a Neuroscience of Aging Perspective | Li KZH; Bherer L; Mirelman A; Maidan I; Hausdorff JM; | 30425679 PERFORM |
| Title: | The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond | ||||
| Authors: | Villeneuve S, Poirier J, Breitner JCS, Tremblay-Mercier J, Remz J, Raoult JM, Yakoub Y, Gallego-Rudolf J, Qiu T, Valdez AF, Mohammediyan B, Javanray M, Metz A, Sanami S, Ourry V, Wearn A, Pastor-Bernier A, Edde M, Gonneaud J, Strikwerda-Brown C, Tardif CL, Gauthier CJ, Descoteaux M, Dadar M, Vachon-Presseau É, Baril AA, Ducharme S, Montembeault M, Geddes MR, Soucy JP, Rajah N, Laforce R, Bocti C, Davatzikos C, Bellec L, Rosa-Neto P, Baillet S, Evans AC, Collins DL, Chakravarty MM, Blennow K, Zetterberg H, S | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40778177/ | ||||
| DOI: | 10.1101/2025.07.22.25331791 | ||||
| Publication: | medRxiv : the preprint server for health sciences | ||||
| Keywords: | Biomarkers; clinical progression; cognition; data repository; neuroimaging; preclinical; | ||||
| PMID: | 40778177 | Category: | Date Added: | 2025-08-19 | |
| Dept Affiliation: |
PSYCHOLOGY
1 StoP-AD Centre, Douglas Mental Health University Institute, McGill University, Montréal, QC H4H 1R3, Canada. 2 Department of Psychiatry, McGill University, Montréal, QC H3A 1A1, Canada. 3 McConnell Brain Imaging Center, Montreal Neurological Institute, McGill University, Montréal, QC H3A 2B4, Canada. 4 Cerebral Imaging Centre, Douglas Mental Health University Institute, McGill University, Montréal, QC H4H 1R3, Canada. 5 Integrated Program in Neuroscience, McGill University, Montréal, QC H3A 0G4, Canada. 6 Research Center of the CIUSSS-NIM, Hôpital du Sacré-Coeur de Montréal, Montreal, QC H4J 1C5, Canada. 7 Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada. 8 Department of Physics, Concordia University, Montréal, QC H4B 1R6, Canada. 9 Department of Neurology and Neurosurgery, McGill University, Montréal, QC H3A 1A1, Canada. 10 Faculté des sciences, Département d'informatique, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada. 11 Normandie Univ, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", NeuroPresage Team, GIP Cyceron, 14032 Caen, France. 12 School of Psychological Science, The University of Western Australia, Perth, Western Australia 6009, Australia. 13 Department Biomedical Engineering, McGill University, Montréal, QC H3A 2B4, Canada. 14 Centre ÉPIC, Montreal Heart Institute, Montréal, QC H1T 1N6, Canada. 15 Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, QC H3A 1G1, Canada. 16 Department of Anesthesia, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC H3G 2M1, Canada. 17 Alan Edwards Center for Research on Pain, McGill University, Montreal, QC H3A 2B4, Canada. 18 Department of Psychology, Toronto Metropolitan University, Toronto, ON M5S 2E5, Canada. 19 Clinique interdisciplinaire de mémoire, CHU de Québec affilié à l'Université Laval, Québec, QC G1V 4G2, Canada. 20 Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC J1H 5H3, Canada. 21 AI2D Center for AI and Data Science for Integrated Diagnostics, University of Pennsylvania, Philadelphia, PA 19104, USA. 22 Psychology Department, Université de Montréal, Montréal, QC H2V 2S9, Canada. 23 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, QC H3W 1W5, Canada. 24 Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 431 39 Mölndal, Sweden. 25 Clinical Neurochemistry Lab, Sahlgrenska University Hospital, 43180 Mölndal, Sweden. 26 Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, 75013 Paris, France. 27 Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, and Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, Anhui, 230026 P.R. China. 28 Department of Neurodegenerative Disease, University College London Institute of Neurology, London WC1E 6BT, UK. 29 UK Dementia Research Institute at UCL, London NW1 3BT, UK. 30 Hong Kong Center for Neurodegenerative Diseases, InnoHK, 999077 Hong Kong, China. 31 Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53792, USA. 32 Department of Physiology and Pharmacology, Université de Montréal, Montréal, QC H3C 3J7, Canada. 33 Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 224 41 Lund, Sweden. |
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Description: |
The PREVENT-AD is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now been followed annually for more than 12 years [median follow-up 8.0 years,SD 3.1]. Multimodal MRI, genetic, neurosensory, clinical, cerebrospinal fluid and cognitive data collected until 2017 on 348 participants who agreed to open sharing with the neuroscience community were already available. We now share a new release including 6 years of additional follow-up cognitive data, and additional MRI follow-ups, clinical progression, new longitudinal behavioral and lifestyle measures (questionnaires, actigraphy), longitudinal AD plasma biomarkers, amyloid-beta and tau PET, magnetoencephalography, as well as neuroimaging analytic measures from all MRI modalities. We describe the PREVENT-AD study, the data shared with the global research community as well as the model we created to sustain longitudinal follow-ups while also allowing new innovative data collection. |



