Keyword search (4,163 papers available)

"Dopamine" Keyword-tagged Publications:

Title Authors PubMed ID
1 Dopamine inhibits excitatory synaptic responses in layer I of the rat parasubiculum Carter F; Hobishi H; Chapman CA; 40818632
PSYCHOLOGY
2 Insights into dietary phytochemicals targeting Parkinson's disease key genes and pathways: A network pharmacology approach Sasikumar DSN; Thiruselvam P; Sundararajan V; Ravindran R; Gunasekaran S; Madathil D; Kaliamurthi S; Peslherbe GH; Selvaraj G; Sudhakaran SL; 38460310
CHEMBIOCHEM
3 Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms Pando-Naude V; Matthews TE; Højlund A; Jakobsen S; Østergaard K; Johnsen E; Garza-Villarreal EA; Witek MAG; Penhune V; Vuust P; 37724707
PSYCHOLOGY
4 Behavioral, Neural, and Molecular Mechanisms of Conditioned Mate Preference: The Role of Opioids and First Experiences of Sexual Reward Gonzalo R Quintana 36012194
PSYCHOLOGY
5 The Convergence Model of Brain Reward Circuitry: Implications for Relief of Treatment-Resistant Depression by Deep-Brain Stimulation of the Medial Forebrain Bundle Pallikaras V; Shizgal P; 35431828
PSYCHOLOGY
6 The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands Howland JG; Ito R; Lapish CC; Villaruel FR; 35131398
PSYCHOLOGY
7 The trade-off between pulse duration and power in optical excitation of midbrain dopamine neurons approximates Bloch's law Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P; 34864162
PSYCHOLOGY
8 Anxiety-like behavior in female mice is modulated by STAT3 signaling in midbrain dopamine neurons Fernandes MF; Lau D; Sharma S; Fulton S; 33872705
CSBN
9 Neural substrates of appetitive and aversive prediction error. Iordanova MD, Yau JO, McDannald MA, Corbit LH 33453307
CSBN
10 Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value. Mendoza JA, Lafferty CK, Yang AK, Britt JP 31693885
CSBN
11 High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats. Madularu D, Kulkarni P, Yee JR, Kenkel WM, Shams WM, Ferris CF, Brake WG 27154458
CSBN
12 Ventral Midbrain NMDA Receptor Blockade: From Enhanced Reward and Dopamine Inactivation. Hernandez G, Cossette MP, Shizgal P, Rompré PP 27616984
PSYCHOLOGY
13 Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment. Servonnet A, Minogianis EA, Bouchard C, Bédard AM, Lévesque D, Rompré PP, Samaha AN 28522313
CSBN
14 Microbial Factories for the Production of Benzylisoquinoline Alkaloids. Narcross L, Fossati E, Bourgeois L, Dueber JE, Martin VJJ 26775900
BIOLOGY
15 Posterior dopamine D2/3 receptors and brain network functional connectivity. Nagano-Saito A, Lissemore JI, Gravel P, Leyton M, Carbonell F, Benkelfat C 28700819
PERFORM

 

Title:High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats.
Authors:Madularu DKulkarni PYee JRKenkel WMShams WMFerris CFBrake WG
Link:https://www.ncbi.nlm.nih.gov/pubmed/27154458?dopt=Abstract
DOI:10.1016/j.yhbeh.2016.04.007
Publication:Hormones and behavior
Keywords:AntipsychoticDopamineEstradiolOvariectomySchizophreniafMRI
PMID:27154458 Category:Horm Behav Date Added:2019-06-20
Dept Affiliation: CSBN
1 Concordia University, Department of Psychology, Center for Studies in Behavioural Neurobiology, 7141 Sherbrooke St. West, Montreal, QC, Canada, H4B 1R6. Electronic address: dan.madularu@gmail.com.
2 Northeastern University, Department of Psychology, Center for Translational Neuroimaging, 360 Huntington Ave, Boston, MA, USA, 02115.
3 Concordia University, Department of Psychology, Center for Studies in Behavioural Neurobiology, 7141 Sherbrooke St. West, Montreal, QC, Canada, H4B 1R6.

Description:

High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats.

Horm Behav. 2016 06;82:56-63

Authors: Madularu D, Kulkarni P, Yee JR, Kenkel WM, Shams WM, Ferris CF, Brake WG

Abstract

The ovarian hormone estrogen has been implicated in schizophrenia symptomatology. Low levels of estrogen are associated with an increase in symptom severity, while exogenous estrogen increases the efficacy of antipsychotic medication, pointing at a possible interaction between estrogen and the dopaminergic system. The aim of this study is to further investigate this interaction in an animal model of some aspects of schizophrenia using awake functional magnetic resonance imaging. Animals receiving 17ß-estradiol and haloperidol were scanned and BOLD activity was assessed in response to amphetamine. High 17ß-estradiol replacement and chronic haloperidol treatment showed increased BOLD activity in regions of interest and neural networks associated with schizophrenia (hippocampal formations, habenula, amygdala, hypothalamus etc.), compared with low, or no 17ß-estradiol. These data show that chronic haloperidol treatment has a sensitizing effect, possibly on the dopaminergic system, and this effect is dependent on hormonal status, with high 17ß-estradiol showing the greatest BOLD increase. Furthermore, these experiments further support the use of imaging techniques in studying schizophrenia, as modeled in the rat, but can be extended to addiction and other disorders.

PMID: 27154458 [PubMed - indexed for MEDLINE]





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