Keyword search (4,163 papers available)

"Episodic memory" Keyword-tagged Publications:

Title Authors PubMed ID
1 The predictive role of olfactory identification on episodic memory and mild cognitive impairment: Results from the CIMA-Q cohort Jobin B; Phillips NA; Frasnelli J; Boller B; 40944318
PSYCHOLOGY
2 Effects of early midlife ovarian removal on sleep: Polysomnography-measured cortical arousal, homeostatic drive, and spindle characteristics Brown A; Gervais NJ; Gravelsins L; O' Byrne J; Calvo N; Ramana S; Shao Z; Bernardini M; Jacobson M; Rajah MN; Einstein G; 39178647
HKAP
3 Olfactory function reflects episodic memory performance and atrophy in the medial temporal lobe in individuals at risk for Alzheimer's disease Papadatos Z; Phillips NA; 37146503
PSYCHOLOGY
4 Taking stock of the past: A psychometric evaluation of the Autobiographical Interview Lockrow AW; Setton R; Spreng KAP; Sheldon S; Turner GR; Spreng RN; 36944860
CONCORDIA

 

Title:Olfactory function reflects episodic memory performance and atrophy in the medial temporal lobe in individuals at risk for Alzheimer's disease
Authors:Papadatos ZPhillips NA
Link:https://pubmed.ncbi.nlm.nih.gov/37146503/
DOI:10.1016/j.neurobiolaging.2023.04.001
Publication:Neurobiology of aging
Keywords:Alzheimer's diseaseEpisodic memoryMild cognitive impairmentOlfactory dysfunctionStructural MRISubjective cognitive decline
PMID:37146503 Category: Date Added:2023-05-06
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montréal, Quebec, Canada.
2 Department of Psychology, Concordia University, Montréal, Quebec, Canada; Center for Research in Human Development (CRDH), Concordia University, Montréal, Quebec, Canada; Centre for Research on Brain, Language & Music (CRBLM), McGill University, Montréal, Quebec, Canada; Bloomfield Centre for Research in Aging, Lady Davis Institute for Medical Research/Jewish General Hospital/McGill University, Montréal, Quebec, Canada. Electronic address: Natalie.Phillips@concordia.ca.

Description:

We examined cognitive domains and brain regions associated with olfactory performance in cognitively unimpaired older adults (CU-OAs) and individuals with or at risk for Alzheimer's Disease (AD). We compared CU-OAs (N = 55), individuals with subjective cognitive decline (SCD, N = 55), mild cognitive impairment (MCI, N = 101), and AD (N = 45) on measures of olfactory function (Brief Smell Identification Test), cognition (episodic and semantic memory), and medial temporal lobe thickness and volume. Analyses controlled for age, sex, education, and total intracranial volume. Olfactory function decreased from SCD to MCI to AD. CU-OAs outperformed all groups except SCDs on tests of cognition and olfaction. Although these measures did not differ between the CU-OAs and SCDs, olfactory function correlated with episodic memory tests and with entorhinal cortex atrophy only in the SCD group. Olfactory function also correlated with hippocampal volume and right-hemisphere entorhinal cortex thickness in the MCI group. Olfactory dysfunction reflects medial temporal lobe integrity and memory performance in a group at risk for AD with normal cognition and olfaction.





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