Keyword search (4,163 papers available)

"Fear" Keyword-tagged Publications:

Title Authors PubMed ID
1 Anxiolytic effects of diazepam in Trinidadian guppies exposed to chemical cues indicating predation risk Crane AL; Feyten LEA; Brusseau AJP; Dumaresq Synnott F; Ramnarine IW; Ferrari MCO; Brown GE; 40905336
CONCORDIA
2 Anxiolytic effects of diazepam in Trinidadian guppies exposed to chemical cues indicating predation risk Crane AL; Feyten LEA; Brusseau AJP; Dumaresq Synnott F; Ramnarine IW; Ferrari MCO; Brown GE; 40905351
CONCORDIA
3 Obsessive-compulsive symptoms moderate the effect of contamination motion on disgust intensity Pelzer M; Ouellet-Courtois C; Krause S; Coughtrey A; Fink-Lamotte J; 40858003
CCRH
4 Development and validation of the multidimensional Fear of Depression Recurrence Questionnaire (FoDRQ) Gumuchian ST; Boyle A; Kennedy G; Wong SF; Ellenbogen MA; 40391691
PSYCHOLOGY
5 Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear-Avoidance Beliefs, Insomnia, and Spinal Degenerative Changes Pinto SM; Cheung JPY; Samartzis D; Karppinen J; Zheng YP; Pang MYC; Fortin M; Wong AYL; 40376565
SOH
6 Self-Ambivalence Is Indirectly Associated With Obsessive-Compulsive and Eating Disorder Symptoms Through Different Feared Self-Themes Wilson S; Mesli N; Mehak A; Racine SE; 40227164
PSYCHOLOGY
7 Cultural Adaptation and Validation of the Athlete Fear-Avoidance Questionnaire in Arabic: Preliminary Analysis of Fear-Avoidance in ACL-Reconstructed Recreational Players Alanazi R; Kashoo FZ; Alrashdi N; Alanazi S; Shaik AR; Sirajudeen MS; Alenazi A; Nambi G; Dover G; Alanazi AD; 40190690
HKAP
8 Integrating past experiences Leir TMW; Gardner MPH; 40146623
PSYCHOLOGY
9 Athlete Fear Avoidance, Depression, and Anxiety Are Associated with Acute Concussion Symptoms in Athletes Patlan I; Gamelin G; Khalaj K; Castonguay T; Dover G; 38673675
HKAP
10 Fear of depression recurrence among individuals with remitted depression: a qualitative interview study Stephanie T Gumuchian 38383311
PSYCHOLOGY
11 What is Learned Determines How Pavlovian Conditioned Fear is Consolidated in the Brain Leake J; Leidl DM; Lay BPP; Fam JP; Giles MC; Qureshi OA; Westbrook RF; Holmes NM; 37963767
CSBN
12 NMDA Receptors in the Basolateral Amygdala Complex Are Engaged for Pavlovian Fear Conditioning When an Animal's Predictions about Danger Are in Error Tuval Keidar 37607821
CSBN
13 Can immorality be contracted? Appraisals of moral disgust and contamination fear Ouellet-Courtois C; Radomsky AS; 37270955
PSYCHOLOGY
14 Danger Changes the Way the Brain Consolidates Neutral Information; and Does So by Interacting with Processes Involved in the Encoding of That Information Omar A Qureshi 36927572
PSYCHOLOGY
15 The fear of losing control Adam S Radomsky 36113905
PSYCHOLOGY
16 Alarm cues and alarmed conspecifics: neural activity during social learning from different cues in Trinidadian guppies Raina Fan 36043284
CSBN
17 Experimental chambers Persistent disruption of overexpectation learning after inactivation of the lateral orbitofrontal cortex in male rats Lay BPP; Choudhury R; Esber GR; Iordanova MD; 35932299
PSYCHOLOGY
18 Prediction error determines whether NMDA receptors in the basolateral amygdala complex are involved in Pavlovian fear conditioning Williams-Spooner MJ; Delaney AJ; Westbrook RF; Holmes NM; 35410880
PSYCHOLOGY
19 The rodent medial prefrontal cortex and associated circuits in orchestrating adaptive behavior under variable demands Howland JG; Ito R; Lapish CC; Villaruel FR; 35131398
PSYCHOLOGY
20 Mechanisms of higher-order learning in the amygdala Gostolupce D; Iordanova MD; Lay BPP; 34197867
PSYCHOLOGY
21 Association Between Pain Catastrophizing and Pain and Cardiovascular Changes During a Cold-Pressor Test in Athletes Lentini M; Scalia J; Lebel FB; Touma F; Jhajj A; Darlington PJ; Dover G; 34000018
PERFORM
22 Development and validation of the multidimensional version of the Fear of Self Questionnaire: Corrupted, culpable and malformed feared possible selves in obsessive-compulsive and body-dysmorphic symptoms. Aardema F, Radomsky AS, Moulding R, Wong SF, Bourguignon L, Giraldo-O'Meara M 33547834
PSYCHOLOGY
23 Neural substrates of appetitive and aversive prediction error. Iordanova MD, Yau JO, McDannald MA, Corbit LH 33453307
CSBN
24 Pain catastrophizing in athletes correlates with pain and cardiovascular changes during a painful cold pressor test Matylda L; Joseph S; Frédérike BL; Fadi T; Aneet J; Darlington PJ; Dover G; 33150380
PERFORM
25 Different methods of fear reduction are supported by distinct cortical substrates. Lay BP, Pitaru AA, Boulianne N, Esber GR, Iordanova MD 32589138
PSYCHOLOGY
26 Failure of fear extinction in insomnia: An evolutionary perspective. Perogamvros L, Castelnovo A, Samson D, Dang-Vu TT 32143023
PERFORM
27 An ecological framework of neophobia: from cells to organisms to populations. Crane AL, Brown GE, Chivers DP, Ferrari MCO 31599483
BIOLOGY
28 The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study. Payette MC, Bélanger C, Benyebdri F, Filiatrault J, Bherer L, Bertrand JA, Nadeau A, Bruneau MA, Clerc D, Saint-Martin M, Cruz-Santiago D, Ménard C, Nguyen P, Vu TTM, Comte F, Bobeuf F, Grenier S 28452660
PERFORM

 

Title:Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear-Avoidance Beliefs, Insomnia, and Spinal Degenerative Changes
Authors:Pinto SM,  Cheung JPY,  Samartzis D,  Karppinen J,  Zheng YP,  Pang MYC,  Fortin M,  Wong AYL
Link:https://pubmed.ncbi.nlm.nih.gov/40376565/
DOI:10.1002/jsp2.70071
Publication:JOR spine
Keywords:Modic changes;  chronic low back pain;  facet joint degeneration;  fear avoidance beliefs;  insomnia;  lumbar multifidus; 
PMID:40376565 Category: Date Added:2025-05-16
Dept Affiliation: SOH
1 Department of Rehabilitation Sciences The Hong Kong Polytechnic University Hong Kong SAR China.
2 Department of Orthopaedics and Traumatology The University of Hong Kong Hong Kong SAR China.
3 Department of Orthopaedics Surgery Rush University Medical Center Chicago Illinois USA.
4 Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland.
5 Rehabilitation Services of Wellbeing Services County of South Karelia Lappeenranta Finland.
6 Research Unit of Health Sciences and Technology University of Oulu Oulu Finland.
7 Department of Biomedical Engineering The Hong Kong Polytechnic University Hong Kong SAR China.
8 Department of Health, Kinesiology & Applied Physiology Concordia University Montreal Quebec Canada.
9 School of Health Concordia University Montreal Quebec Canada.
10 Research Institute for Smart Ageing, The Hong Kong Polytechnic University Hong Kong SAR China.

Description:

Background: Although individuals with chronic low back pain (CLBP) show increased fatty infiltration in the lumbar multifidus muscle (LMM), it remains unclear whether LMM changes are related to clinical outcomes (such as pain and disability) after considering confounders (spinal phenotypes, fear-avoidance beliefs [FABs] and insomnia). This study examined: (1) differences in confounders and LMM characteristics between individuals with and without CLBP; and (2) associations between confounders, LMM parameters, and clinical outcomes in the CLBP group alone.

Methods: Participants (CLBP = 70 and asymptomatic people = 67) underwent lumbar magnetic resonance imaging. Outcome measures comprised the numeric pain rating scale, the Roland-Morris Disability Questionnaire, the Fear-Avoidance Beliefs Questionnaire (FABQ), and the Insomnia Severity Index (ISI) Scale. LMM morphometry at L3-S1 (cross-sectional area, total volume, and fatty infiltration) was measured using a customized MATLAB program. Spinal phenotypes (disc degeneration, high-intensity zones, Modic changes [MCs], Schmorl's nodes, facet joint degeneration [FJD], and facet tropism [FT]) were scored. The between-group differences were analyzed using linear mixed models and chi-squared/Fisher's exact tests. Univariate and multivariate analyses evaluated associations between clinical outcomes and other outcome measures in the CLBP group.

Results: The CLBP group demonstrated more severe disc degeneration and FJD at all levels, and greater FT at L5/S1 than asymptomatic participants (p < 0.05). The average LMM total volume at L3/4 and the percentage of fatty infiltration in LMM in the L3-S1 region were greater in the CLBP group than in asymptomatic counterparts (p < 0.05). The presence of MC at L4 and FJD at L4/5 and L4-S1 was significantly related to pain intensity in the CLBP group. Similarly, FABQ-Work and ISI scores were significantly related to pain intensity (explaining 37% of the variance in pain).

Conclusions: The CLBP group displays more fatty infiltration in the LMM, but their LMM morphometric parameters are unrelated to pain/disability after considering spinal phenotypes, FABs, and insomnia.





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