Keyword search (4,163 papers available)

"Ih" Keyword-tagged Publications:

Title Authors PubMed ID
1 Functional analysis of the protocatechuate branch of the β-ketoadipate pathway in Aspergillus niger Sgro M; Chow N; Olyaei F; Arentshorst M; Geoffrion N; Ram AFJ; Powlowski J; Tsang A; 37399977
BIOLOGY
2 TRAPPC11-related muscular dystrophy with hypoglycosylation of alpha-dystroglycan in skeletal muscle and brain Munot P; McCrea N; Torelli S; Manzur A; Sewry C; Chambers D; Feng L; Ala P; Zaharieva I; Ragge N; Roper H; Marton T; Cox P; Milev MP; Liang WC; Maruyama S; Nishino I; Sacher M; Phadke R; Muntoni F; 34648194
BIOLOGY
3 Chronic Neuroleptic-Induced Parkinsonism Examined with Positron Emission Tomography. Galoppin M, Berroir P, Soucy JP, Suzuki Y, Lavigne GJ, Gagnon JF, Montplaisir JY, Stip E, Blanchet PJ 32353194
PERFORM
4 The non-aromatizable androgen dihydrotestosterone (DHT) facilitates sexual behavior in ovariectomized female rats primed with estradiol. Maseroli E, Santangelo A, Lara-Fontes B, Quintana GR, Mac Cionnaith CE, Casarrubea M, Ricca V, Maggi M, Vignozzi L, Pfaus JG 32087523
PSYCHOLOGY
5 Angiotensin-I-Converting Enzyme Inhibitory Activity of Coumarins from Angelica decursiva. Ali MY, Seong SH, Jung HA, Choi JS 31683604
CHEMBIOCHEM
6 Heterosynaptic modulation of evoked synaptic potentials in layer II of the entorhinal cortex by activation of the parasubiculum. Sparks DW, Chapman CA 27146979
PSYCHOLOGY
7 Mining Enzyme Diversity of Transcriptome Libraries through DNA Synthesis for Benzylisoquinoline Alkaloid Pathway Optimization in Yeast. Narcross L, Bourgeois L, Fossati E, Burton E, Martin VJ 27442619
BIOLOGY

 

Title:Heterosynaptic modulation of evoked synaptic potentials in layer II of the entorhinal cortex by activation of the parasubiculum.
Authors:Sparks DW,  Chapman CA
Link:https://www.ncbi.nlm.nih.gov/pubmed/27146979?dopt=Abstract
DOI:10.1152/jn.00095.2016
Publication:Journal of neurophysiology
Keywords:Ih;  entorhinal cortex;  heterosynaptic;  parasubiculum;  plasticity; 
PMID:27146979 Category:J Neurophysiol Date Added:2019-06-20
Dept Affiliation: PSYCHOLOGY
1 Centre for Studies in Behavioural Neurobiology, Department of Psychology, Concordia University, Montréal, Québec, Canada.
2 Centre for Studies in Behavioural Neurobiology, Department of Psychology, Concordia University, Montréal, Québec, Canada andrew.chapman@concordia.ca.

Description:

Heterosynaptic modulation of evoked synaptic potentials in layer II of the entorhinal cortex by activation of the parasubiculum.

J Neurophysiol. 2016 08 01;116(2):658-70

Authors: Sparks DW, Chapman CA

Abstract

The superficial layers of the entorhinal cortex receive sensory and associational cortical inputs and provide the hippocampus with the majority of its cortical sensory input. The parasubiculum, which receives input from multiple hippocampal subfields, sends its single major output projection to layer II of the entorhinal cortex, suggesting that it may modulate processing of synaptic inputs to the entorhinal cortex. Indeed, stimulation of the parasubiculum can enhance entorhinal responses to synaptic input from the piriform cortex in vivo. Theta EEG activity contributes to spatial and mnemonic processes in this region, and the current study assessed how stimulation of the parasubiculum with either single pulses or short, five-pulse, theta-frequency trains may modulate synaptic responses in layer II entorhinal stellate neurons evoked by stimulation of layer I afferents in vitro. Parasubicular stimulation pulses or trains suppressed responses to layer I stimulation at intervals of 5 ms, and parasubicular stimulation trains facilitated layer I responses at a train-pulse interval of 25 ms. This suggests that firing of parasubicular neurons during theta activity may heterosynaptically enhance incoming sensory inputs to the entorhinal cortex. Bath application of the hyperpolarization-activated cation current (Ih) blocker ZD7288 enhanced the facilitation effect, suggesting that cholinergic inhibition of Ih may contribute. In addition, repetitive pairing of parasubicular trains and layer I stimulation induced a lasting depression of entorhinal responses to layer I stimulation. These findings provide evidence that theta activity in the parasubiculum may promote heterosynaptic modulation effects that may alter sensory processing in the entorhinal cortex.

PMID: 27146979 [PubMed - indexed for MEDLINE]




BookR developed by Sriram Narayanan
for the Concordia University School of Health
Copyright © 2011-2026
Cookie settings
Concordia University