Keyword search (4,163 papers available)

"Placebo" Keyword-tagged Publications:

Title Authors PubMed ID
1 The Role of Sleep in Learning Placebo Effects. Chouchou F, Dang-Vu TT, Rainville P, Lavigne G 30146053
PERFORM

 

Title:The Role of Sleep in Learning Placebo Effects.
Authors:Chouchou F,  Dang-Vu TT,  Rainville P,  Lavigne G
Link:https://www.ncbi.nlm.nih.gov/pubmed/30146053?dopt=Abstract
DOI:10.1016/bs.irn.2018.07.013
Publication:International review of neurobiology
Keywords:Conditioning;  Expectations;  Pain;  Placebo;  REM sleep;  Relief;  Sleep; 
PMID:30146053 Category:Int Rev Neurobiol Date Added:2019-05-31
Dept Affiliation: PERFORM
1 PERFORM Center & Department of Exercise Science, Concordia University, Montreal, QC, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Montreal, QC, Canada.
2 Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Université de Montréal, Montreal, QC, Canada; Faculté de Médecine Dentaire, Université de Montréal, Montreal, QC, Canada.
3 Faculté de Médecine Dentaire, Université de Montréal, Montreal, QC, Canada; Centre d'Etudes Avancées en Médecine du Sommeil, Hôpital du Sacré-Coeur de Montréal, Montreal, QC, Canada. Electronic address: gilles.lavigne@umontreal.ca.

Description:

The Role of Sleep in Learning Placebo Effects.

Int Rev Neurobiol. 2018;139:321-355

Authors: Chouchou F, Dang-Vu TT, Rainville P, Lavigne G

Abstract

The placebo effect is a psychobiological phenomenon producing clinical benefits attributed to a wide range of neurobiological mechanisms. Independently from placebo effects, these mechanisms may also be under the influence of processes that can take place during sleep. The relationship between sleep and placebo effects has received very little attention. Three experimental studies, conducted on healthy subjects, have examined sleep changes following placebo conditioning associated with analgesic suggestions and the effects of sleep deprivation on placebo effects. A relation between rapid eye movement (REM) sleep, expectations of relief and placebo analgesia was observed in which REM sleep deprivation seems to improve placebo-induced expectations and analgesia. Moreover, analgesic expectations developed before sleep produced a reduction in cortical arousals evoked by noxious stimuli during REM sleep. In this article, we describe sleep and pain/analgesia interactions, the relationship between sleep and placebo analgesia, and finally the potential mechanisms underlying this relationship.

PMID: 30146053 [PubMed - indexed for MEDLINE]




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