Keyword search (4,164 papers available)

"Prognosis" Keyword-tagged Publications:

Title Authors PubMed ID
1 Microfluidic Liquid Biopsy Minimally Invasive Cancer Diagnosis by Nano-Plasmonic Label-Free Detection of Extracellular Vesicles: Review Neriya Hegade KP; Bhat RB; Packirisamy M; 40650129
ENCS
2 5P Risk Classification Predicts Performance on Self-Reported but Not Objective Clinical Outcomes at 4-Weeks Post-Concussion in Children Teel E; Brossard-Racine M; Corbin-Berrigan LA; Gagnon I; 39988038
HKAP
3 Pattern and Visual Prognostic Factors of Behcet's Uveitis in Northwest Iran Alizadeh Ghavidel L; Bagheri M; Mousavi F; Rezaei L; Hazeri S; Hashemi HS; 35765637
BIOLOGY
4 Circulating miR-1246 Targeting UBE2C, TNNI3, TRAIP, UCHL1 Genes and Key Pathways as a Potential Biomarker for Lung Adenocarcinoma: Integrated Biological Network Analysis Huang S; Wei YK; Kaliamurthi S; Cao Y; Nangraj AS; Sui X; Chu D; Wang H; Wei DQ; Peslherbe GH; Selvaraj G; Shi J; 33050659
CHEMBIOCHEM

 

Title:5P Risk Classification Predicts Performance on Self-Reported but Not Objective Clinical Outcomes at 4-Weeks Post-Concussion in Children
Authors:Teel EBrossard-Racine MCorbin-Berrigan LAGagnon I
Link:https://pubmed.ncbi.nlm.nih.gov/39988038/
DOI:10.1016/j.apmr.2025.02.008
Publication:Archives of physical medicine and rehabilitation
Keywords:adolescentsbrain injury (traumatic)childrenfatigueprognosis
PMID:39988038 Category: Date Added:2025-02-24
Dept Affiliation: HKAP
1 Department of Health, Kinesiology, & Applied Physiology, Concordia University, Montreal, QC, Canada. Electronic address: elizabeth.teel@concordia.ca.
2 School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada; Division of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada; Department of Neurology and Neurosurgery, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.
3 Département des Sciences de l'Activité Physique, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada.
4 School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada; Division of Pediatric Emergency Medicine, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.

Description:

Objective: To determine if performance on symptom, cognitive, balance, fatigue, physical activity, and quality of life outcomes at 4-weeks post-injury in children with concussion differs based on acute 5P risk classification.

Design: Prospective cohort.

Setting: Laboratory.

Patients: Sixty-two children (age: 13.27 ± 2.50 years; 29 (46.7%) females) with diagnosed concussion.

Interventions: Not applicable.

Main outcome measures: Patient demographics and post-injury assessments were completed within 72 hours of concussion and used to classify patients as "high", "moderate", or "low" PPCS risk. Children then completed a multi-modal assessment battery at 4-weeks post-concussion. Kruskal-Wallis assessments analyzed whether study outcomes differed between 5P risk groups.

Results: Significant group differences were observed in symptom (?2(2)= 9.76, p=0.008), fatigue (?2(2)= 14.60, p<0.001), physical activity (?2(2)= 15.76, p<0.001), and quality of life (?2(2)= 7.82, p=0.02) outcomes. The low-risk group had fewer symptoms and less fatigue but increased physical activity levels and quality of life compared to the high-risk group. No significant differences in cognitive or balance outcomes were observed (p>0.05).

Conclusion: The 5P rule provides clinicians with valuable prognostic information related to PPCS and self-reported outcomes 4-weeks post-concussion, but not objective cognitive or balance outcomes. This information may help clinicians prioritize treatment resources to children most at-risk of prolonged concussion recovery.





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