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PubMed Publications| Keyword search (4,163 papers available) |  |
"biomarker" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | ADPv2: A hierarchical histological tissue type-annotated dataset for potential biomarker discovery of colorectal disease | Yang Z; Li K; Ramandi SG; Brassard P; Khellaf A; Trinh VQ; Zhang J; Chen L; Rowsell C; Varma S; Plataniotis K; Hosseini MS; | 41658283 ENCS |
| 2 | The PREVENT-AD cohort: Accelerating Alzheimer s disease research and treatment in Canada and beyond | Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Fajardo Valdez A; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterbe | 41020412 SOH |
| 3 | Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics | Abicumaran Uthamacumaran | 40848317 PSYCHOLOGY |
| 4 | The PREVENT-AD cohort: accelerating Alzheimer s disease research and treatment in Canada and beyond | Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda-Brown C; Tardif CL; Gauthier CJ; Descoteaux M; Dadar M; Vachon-Presseau É; Baril AA; Ducharme S; Montembeault M; Geddes MR; Soucy JP; Rajah N; Laforce R; Bocti C; Davatzikos C; Bellec L; Rosa-Neto P; Baillet S; Evans AC; Collins DL; Chakravarty MM; Blennow K; Zetterberg H; S | 40778177 PSYCHOLOGY |
| 5 | Exosome Innovations in Ophthalmology and Sjögren s Syndrome | Wu KY; Dave A; Nirwal GK; Giunta M; Nguyen VDH; Tran SD; | 40360847 CONCORDIA |
| 6 | Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease | Páez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbé F; Dang-Vu TT; Ripoll GP; | 39878233 CONCORDIA |
| 7 | A multimodal neuroimaging study of youth at risk for substance use disorders: Functional magnetic resonance imaging and [18F]fallypride positron emission tomography | Nikolic M; Cox SML; Jaworska N; Castellanos-Ryan N; Dagher A; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M; | 39725679 CSBN |
| 8 | Isotopic and molecular analyses of n-alkanes in a temporal study of coastal sediment contributions to organic carbon degradation induced by algal bloom and terrestrial runoff | Mirzaei Y; Douglas PMJ; Gélinas Y; | 39700996 CHEMBIOCHEM |
| 9 | Alzheimer's early detection in post-acute COVID-19 syndrome: a systematic review and expert consensus on preclinical assessments | Vandersteen C; Plonka A; Manera V; Sawchuk K; Lafontaine C; Galery K; Rouaud O; Bengaied N; Launay C; Guérin O; Robert P; Allali G; Beauchet O; Gros A; | 37416323 CONCORDIA |
| 10 | New metabolic signature for Chagas disease reveals sex steroid perturbation in humans and mice | Golizeh M; Nam J; Chatelain E; Jackson Y; Ohlund LB; Rasoolizadeh A; Camargo FV; Mahrouche L; Furtos A; Sleno L; Ndao M; | 36590505 CHEMBIOCHEM |
| 11 | Defective GaAs nanoribbon-based biosensor for lung cancer biomarkers: a DFT study | Tarun T; Singh P; Kaur H; Walia GK; Randhawa DKK; Choudhary BC; | 34459994 ENCS |
| 12 | Tools and Techniques for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)/COVID-19 Detection | Safiabadi Tali SH; LeBlanc JJ; Sadiq Z; Oyewunmi OD; Camargo C; Nikpour B; Armanfard N; Sagan SM; Jahanshahi-Anbuhi S; | 33980687 IMAGING |
| 13 | Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain Study. | Pieruccini-Faria F, Black SE, Masellis M, Smith EE, Almeida QJ, Li KZH, Bherer L, Camicioli R, Montero-Odasso M | 33590967 PSYCHOLOGY |
| 14 | Methodological and clinical challenges associated with biomarkers for psychiatric disease: A scoping review. | Kirkpatrick RH; Munoz DP; Khalid-Khan S; Booij L; | 33221025 PSYCHOLOGY |
| 15 | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R; | 33094146 CRDH |
| 16 | Evidence of a Relation Between Hippocampal Volume, White Matter Hyperintensities, and Cognition in Subjective Cognitive Decline and Mild Cognitive Impairment | Caillaud M; Hudon C; Boller B; Brambati S; Duchesne S; Lorrain D; Gagnon JF; Maltezos S; Mellah S; Phillips N; Belleville S; | 31758692 CRDH |
| 17 | The Comprehensive Assessment of Neurodegeneration and Dementia: Canadian Cohort Study. | Chertkow H, Borrie M, Whitehead V, Black SE, Feldman HH, Gauthier S, Hogan DB, Masellis M, McGilton K, Rockwood K, Tierney MC, Andrew M, Hsiung GR, Camicioli R, Smith EE, Fogarty J, Lindsay J, Best S, Evans A, Das S, Mohaddes Z, Pilon R, Poirier J, Phillips NA, MacNamara E, Dixon RA, Duchesne S, MacKenzie I, Rylett RJ | 31309917 PSYCHOLOGY |
| 18 | Parental Nutrition Knowledge Rather Than Nutrition Label Use Is Associated With Adiposity in Children. | Kakinami L, Houle-Johnson S, McGrath JJ | 27373860 PERFORM |
| 19 | Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment. | Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J | 28522082 PERFORM |
| 20 | Sleep spindles may predict response to cognitive-behavioral therapy for chronic insomnia | Dang-Vu TT; Hatch B; Salimi A; Mograss M; Boucetta S; O' Byrne J; Brandewinder M; Berthomier C; Gouin JP; | 29157588 PERFORM |
| 21 | Gross Motor Skills Training Leads to Increased Brain-Derived Neurotrophic Factor Levels in Healthy Older Adults: A Pilot Study. | Grégoire CA, Berryman N, St-Onge F, Vu TTM, Bosquet L, Arbour N, Bherer L | 31031639 PERFORM |
| 22 | Biomarkers, designs, and interpretations of resting-state fMRI in translational pharmacological research: A review of state-of-the-Art, challenges, and opportunities for studying brain chemistry. | Khalili-Mahani N, Rombouts SA, van Osch MJ, Duff EP, Carbonell F, Nickerson LD, Becerra L, Dahan A, Evans AC, Soucy JP, Wise R, Zijdenbos AP, van Gerven JM | 28145075 PERFORM |
| Title: | CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus | ||||
| Authors: | Montero-Odasso M, Pieruccini-Faria F, Ismail Z, Li K, Lim A, Phillips N, Kamkar N, Sarquis-Adamson Y, Speechley M, Theou O, Verghese J, Wallace L, Camicioli R | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/33094146/ | ||||
| DOI: | 10.1002/trc2.12068 | ||||
| Publication: | Alzheimer s & dementia (New York, N. Y.) | ||||
| Keywords: | behavior; biomarker; cognitive impairment; dementia; frailty; gait; hearing; olfaction; parkinsonism; prediction; risk; sleep; vision; | ||||
| PMID: | 33094146 | Category: | Alzheimers Dement (N Y) | Date Added: | 2020-10-24 |
| Dept Affiliation: |
CRDH
1 Gait and Brain Laboratory Parkwood Institute Lawson Health Research Institute London Ontario Canada. 2 Division of Geriatric Medicine Department of Medicine Schulich School of Medicine and Dentistry London Ontario Canada. 3 Department of Epidemiology and Biostatistics University of Western Ontario London Ontario Canada. 4 Departments of Psychiatry Clinical Neurosciences and Community Health Sciences Hotchkiss Brain Institute and O'Brien Institute for Public Health University of Calgary Calgary Alberta Canada. 5 Centre for Research in Human Development Concordia University Montreal Quebec Canada. 6 Department of Psychology Concordia University Quebec Canada. 7 Division of Neurology Department of Medicine Sunnybrook Health Sciences Centre Toronto Ontario Canada. 8 School of Physiotherapy Dalhousie University Halifax Nova Scotia Canada. 9 Department of Medicine Dalhousie University Halifax Nova Scotia Canada. 10 Department of Neurology Albert Einstein College of Medicine Bronx New York USA. 11 Division of Neurology Department of Medicine University of Alberta Edmonton Alberta Canada. |
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Description: |
Introduction: Cognitive impairment is the hallmark of Alzheimer's disease (AD) and related dementias. However, motor decline has been recently described as a prodromal state that can help to detect at-risk individuals. Similarly, sensory changes, sleep and behavior disturbances, and frailty have been associated with higher risk of developing dementia. These clinical findings, together with the recognition that AD pathology precedes the diagnosis by many years, raises the possibility that non-cognitive changes may be early and non-invasive markers for AD or, even more provocatively, that treating non-cognitive aspects may help to prevent or treat AD and related dementias. Methods: A subcommittee of the Canadian Consensus Conference on Diagnosis and Treatment of Dementia reviewed areas of emerging evidence for non-cognitive markers of dementia. We examined the literature for five non-cognitive domains associated with future dementia: motor, sensory (hearing, vision, olfaction), neuro-behavioral, frailty, and sleep. The Grading of Recommendations Assessment, Development, and Evaluation system was used to assign the strength of the evidence and quality of the recommendations. We provide recommendations to primary care clinics and to specialized memory clinics, answering the following main questions: (1) What are the non-cognitive and functional changes associated with risk of developing dementia? and (2) What is the evidence that sensory, motor, behavioral, sleep, and frailty markers can serve as potential predictors of dementia? Results: Evidence supported that gait speed, dual-task gait speed, grip strength, frailty, neuropsychiatric symptoms, sleep measures, and hearing loss are predictors of dementia. There was insufficient evidence for recommending assessing olfactory and vision impairments as a predictor of dementia. Conclusions: Non-cognitive markers can assist in identifying people at risk for cognitive decline or dementia. These non-cognitive markers may represent prodromal symptoms and several of them are potentially amenable to treatment that might delay the onset of cognitive decline. |
