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PubMed Publications| Keyword search (4,163 papers available) |  |
"depressive disorder" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Development and validation of the multidimensional Fear of Depression Recurrence Questionnaire (FoDRQ) | Gumuchian ST; Boyle A; Kennedy G; Wong SF; Ellenbogen MA; | 40391691 PSYCHOLOGY |
| 2 | Depression Screening and Health Outcomes in Children and Adolescents: A Systematic Review | Roseman M; Saadat N; Riehm KE; Kloda LA; Boruff J; Ickowicz A; Baltzer F; Katz LY; Patten SB; Rousseau C; Thombs BD; | 28851234 LIBRARY |
| 3 | The effects of intranasal oxytocin on the efficacy of psychotherapy for major depressive disorder: a pilot randomized controlled trial | Ellenbogen MA; Cardoso C; Serravalle L; Vadaga K; Joober R; | 38445382 PSYCHOLOGY |
| 4 | Editorial: Neuroepigenetics and biological mechanisms of stress-induced socio-cognitive changes | Daniels WMU; Ajonijebu DC; Olajide OJ; | 38445046 CSBN |
| 5 | Fear of depression recurrence among individuals with remitted depression: a qualitative interview study | Stephanie T Gumuchian | 38383311 PSYCHOLOGY |
| 6 | Symptoms characteristics of personality disorders associated with suicidal ideation and behaviors in a clinical sample of adolescents with a depressive disorder | Gifuni AJ; Spodenkiewicz M; Laurent G; MacNeil S; Jollant F; Renaud J; | 38146283 PSYCHOLOGY |
| 7 | The effects of walking in nature on negative and positive affect in adult psychiatric outpatients with major depressive disorder: A randomized-controlled study | Watkins-Martin K; Bolani D; Richard-Devantoy S; Pennestri MH; Malboeuf-Hurtubise C; Philippe F; Guindon J; Gouin JP; Ouellet-Morin I; Geoffroy MC; | 36058362 PSYCHOLOGY |
| 8 | Probability of Major Depression Classification Based on the SCID, CIDI, and MINI Diagnostic Interviews: A Synthesis of Three Individual Participant Data Meta-Analyses | Wu Y; Levis B; Ioannidis JPA; Benedetti A; Thombs BD; | 32814337 LIBRARY |
| 9 | The Neuroscience of Sadness: A Multidisciplinary Synthesis and Collaborative Review for the Human Affectome Project. | Arias JA, Williams C, Raghvani R, Aghajani M, Baez S, Belzung C, Booij L, Busatto G, Chiarella J, Fu CH, Ibanez A, Liddell BJ, Lowe L, Penninx BWJH, Rosa P, Kemp AH | 32001274 PSYCHOLOGY |
| 10 | Probability of major depression diagnostic classification based on the SCID, CIDI and MINI diagnostic interviews controlling for Hospital Anxiety and Depression Scale - Depression subscale scores: An individual participant data meta-analysis of 73 primary studies | Wu Y; Levis B; Sun Y; Krishnan A; He C; Riehm KE; Rice DB; Azar M; Yan XW; Neupane D; Bhandari PM; Imran M; Chiovitti MJ; Saadat N; Boruff JT; Cuijpers P; Gilbody S; McMillan D; Ioannidis JPA; Kloda LA; Patten SB; Shrier I; Ziegelstein RC; Henry M; Ismail Z; Loiselle CG; Mitchell ND; Tonelli M; Al-Adawi S; Beraldi A; Braeken APBM; Büel-Drabe N; Bunevicius A; Carter G; Chen CK; Cheung G; Clover K; Conroy RM; Cukor D; da Rocha E Silva CE; Dabscheck E; Daray FM; Douven E; Downing MG; Feinstein A; Ferentinos PP; Fischer FH; Flint AJ; Fujimori M; Gallagher P; Gandy M; Goebel S; Grassi L; Härter M; Jenewein J; Jetté N; Julião M; Kim JM; Kim SW; Kjærgaard M; Köhler S; Loosman WL; Löwe B; Martin-Santos R; Massardo L; Matsuoka Y; Mehnert A; Michopoulos I; Misery L; Navines R; O' Donnell ML; Öztürk A; Peceliuniene J; Pintor L; Ponsford JL; Quinn TJ; Reme SE; Reuter K; Rooney AG; Sánchez-González R; Schwarzbold ML; Senturk Cankorur V; Shaaban J; Sharpe L; Sharpe M; Simard S; Singer S; Stafford L; Stone J; Sultan S; Teixeira AL; Tiringer I; Turner A; Walker J; Walterfang M; Wang LJ; White J; Wong DK; Benedetti A; Thombs BD; | 31911325 LIBRARY |
| 11 | Comparison of major depression diagnostic classification probability using the SCID, CIDI, and MINI diagnostic interviews among women in pregnancy or postpartum: An individual participant data meta-analysis | Levis B; McMillan D; Sun Y; He C; Rice DB; Krishnan A; Wu Y; Azar M; Sanchez TA; Chiovitti MJ; Bhandari PM; Neupane D; Saadat N; Riehm KE; Imran M; Boruff JT; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; Patten SB; Shrier I; Ziegelstein RC; Comeau L; Mitchell ND; Tonelli M; Vigod SN; Aceti F; Alvarado R; Alvarado-Esquivel C; Bakare MO; Barnes J; Beck CT; Bindt C; Boyce PM; Bunevicius A; Couto TCE; Chaudron LH; Correa H; de Figueiredo FP; Eapen V; Fernandes M; Figueiredo B; Fisher JRW; Garcia-Esteve L; Giardinelli L; Helle N; Howard LM; Khalifa DS; Kohlhoff J; Kusminskas L; Kozinszky Z; Lelli L; Leonardou AA; Lewis BA; Maes M; Meuti V; Nakic Radoš S; Navarro García P; Nishi D; Okitundu Luwa E-Andjafono D; Robertson-Blackmore E; Rochat TJ; Rowe HJ; Siu BWM; Skalkidou A; Stein A; Stewart RC; Su KP; Sundström-Poromaa I; Tadinac M; Tandon SD; Tendais I; Thiagayson P; Töreki A; Torres-Giménez A; Tran TD; Trevillion K; Turner K; Vega-Dienstmaier JM; Wynter K; Yonkers KA; Benedetti A; Thombs BD; | 31568624 LIBRARY |
| Title: | The effects of intranasal oxytocin on the efficacy of psychotherapy for major depressive disorder: a pilot randomized controlled trial | ||||
| Authors: | Ellenbogen MA, Cardoso C, Serravalle L, Vadaga K, Joober R | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/38445382/ | ||||
| DOI: | 10.1017/S0033291724000217 | ||||
| Publication: | Psychological medicine | ||||
| Keywords: | intranasal oxytocin; major depressive disorder; psychotherapy; therapeutic alliance; | ||||
| PMID: | 38445382 | Category: | Date Added: | 2024-03-06 | |
| Dept Affiliation: |
PSYCHOLOGY
1 Centre for Research in Human Development, Department of Psychology, Concordia University, Montréal, Canada. 2 The Douglas Research Centre, Department of Psychiatry, McGill University, Montréal, Canada. |
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Description: |
Background: Although both pharmacotherapy and psychological treatments are considered to be efficacious in the treatment of major depressive disorder (MDD), one third of patients do not respond to treatment and many experience residual symptoms post-treatment. In this double-blind placebo-controlled randomized control trial (RCT), we assessed whether intranasal oxytocin (OT) augments the therapeutic efficacy of psychotherapy for MDD and improves the therapeutic alliance. Methods: Twenty-three volunteers (12 female) with MDD underwent 16 sessions of interpersonal therapy. Prior to each session, volunteers self-administered 24 International Units of intranasal OT (n = 12; Syntocinon) or placebo (n = 11). Depressive symptoms were assessed with the Inventory of Depressive Symptomatology at pre- and post-treatment, and at a six month follow-up. Results: Multilevel modeling found a significant effect of OT on the negative slope of depressive symptoms over time (p < 0.05), with medium-large effect sizes at post-treatment (Cohen's d = 0.75) and follow-up (Cohen's d = 0.82). Drug intervention also predicted the intercept when examining the weekly ratings of the therapeutic alliance (p < 0.05), such that volunteers receiving OT, relative to placebo, reported improved therapeutic alliance at session 1. The agreement of goals between therapists and participants, a facet of the therapeutic alliance, mediated the relationship between drug intervention and clinical outcome. Conclusion: In this pilot study, the administration of intranasal OT, relative to placebo, improved the therapeutic alliance at the beginning of therapy and therapeutic efficacy of psychotherapy in persons with MDD. Future RCTs should attempt to replicate these findings in larger samples with different therapeutic modalities (ClinicalTrials.gov: NCT02405715). |
