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PubMed Publications| Keyword search (4,163 papers available) |  |
"fat infiltration" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Ultrasound and MRI-based evaluation of relationships between morphological and mechanical properties of the lower lumbar multifidus muscle in chronic low back pain | Naghdi N; Masi S; Bertrand C; Rosenstein B; Cohen-Adad J; Rivaz H; Roy M; Fortin M; | 40488869 HKAP |
| 2 | MuscleMap: An Open-Source, Community-Supported Consortium for Whole-Body Quantitative MRI of Muscle | McKay MJ; Weber KA; Wesselink EO; Smith ZA; Abbott R; Anderson DB; Ashton-James CE; Atyeo J; Beach AJ; Burns J; Clarke S; Collins NJ; Coppieters MW; Cornwall J; Crawford RJ; De Martino E; Dunn AG; Eyles JP; Feng HJ; Fortin M; Franettovich Smith MM; Galloway G; Gandomkar Z; Glastras S; Henderson LA; Hides JA; Hiller CE; Hilmer SN; Hoggarth MA; Kim B; Lal N; LaPorta L; Magnussen JS; Maloney S; March L; Nackley AG; O' Leary SP; Peolsson A; Perraton Z; Pool-Goudzwaard AL; Schnitzler M; Seitz AL; Semciw AI; Sheard PW; Smith AC; Snodgrass SJ; Sullivan J; Tran V; Valentin S; Walton DM; Wishart LR; Elliott JM; | 39590726 HKAP |
| 3 | Morphological Changes of Deep Extensor Neck Muscles in Relation to the Maximum Level of Cord Compression and Canal Compromise in Patients With Degenerative Cervical Myelopathy | Naghdi N; Elliott JM; Weber MH; Fehlings MG; Fortin M; | 36289049 PERFORM |
| 4 | Paraspinal Muscle Changes in Individuals with and without Chronic Low Back Pain over a 4-Month Period: A Longitudinal MRI Study | Anstruther M; Sean M; Tétreault P; Fortin M; | 38541216 SOH |
| 5 | Thresholding approaches for estimating paraspinal muscle fat infiltration using T1- and T2-weighted MRI: Comparative analysis using water-fat MRI | Ornowski J; Dziesinski L; Hess M; Krug R; Fortin M; Torres-Espin A; Majumdar S; Pedoia V; Bonnheim NB; Bailey JF; | 38222819 HKAP |
| 6 | PILLAR: ParaspInaL muscLe segmentAtion pRoject - a comprehensive online resource to guide manual segmentation of paraspinal muscles from magnetic resonance imaging | Anstruther M; Rossini B; Zhang T; Liang T; Xiao Y; Fortin M; | 37996857 SOH |
| Title: | Ultrasound and MRI-based evaluation of relationships between morphological and mechanical properties of the lower lumbar multifidus muscle in chronic low back pain | ||||
| Authors: | Naghdi N, Masi S, Bertrand C, Rosenstein B, Cohen-Adad J, Rivaz H, Roy M, Fortin M | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/40488869/ | ||||
| DOI: | 10.1007/s00586-025-09012-7 | ||||
| Publication: | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | ||||
| Keywords: | Chronic LBP; Fat infiltration; Lumbar multifidus muscle; MRI; Muscle stiffness; Shear wave elastography; Ultrasound; | ||||
| PMID: | 40488869 | Category: | Date Added: | 2025-06-09 | |
| Dept Affiliation: |
HKAP
1 Department of Health, Kinesiology & Applied Physiology, Concordia University, Montreal, Canada. 2 School of Physical and Occupational Therapy, McGill University, Montreal, Canada. 3 NeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, Canada. 4 Department of Electrical and Computer Engineering, Concordia University, Montreal, Canada. 5 Department of Psychology, McGill University, Montreal, Canada. 6 Department of Health, Kinesiology & Applied Physiology, Concordia University, Montreal, Canada. maryse.fortin@concordia.ca. 7 Centre de Recherche Interdisciplinaire en Readaptation (CRIR), Montreal, Canada. maryse.fortin@concordia.ca. |
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Description: |
Purposes: While lumbar multifidus (MF) muscle alterations are linked to low back pain (LBP), the structure-function relationship is not fully understood. This study aims to evaluate the relationship between fatty degeneration of the lumbar MF muscle and its function in individuals with and without LBP. Methods: The study included 25 participants with chronic nonspecific LBP and 25 age- and sex-matched healthy controls. Participants underwent MRI assessment for MF fat infiltration, utilizing IDEAL fat-water images. Ultrasound measures evaluated MF function, including shear-wave elastography (SWE) for stiffness/elasticity and thickness ratio from rest to submaximal contraction. All measurements were acquired at L4/L5 and L5/S1 spinal levels, bilaterally. Bivariate and multivariable linear regression models were used to assess the relationship between morphology and function, while age, sex, body max index (BMI), physical activity levels, and LBP status were considered as covariates. Results: Fifty participants (26 females) were included (mean age: 39.22 ± 11.67). Greater % MF fat at L4/L5 was significantly associated with greater MF SWE ratio (p = 0.002). No significant bivariate or multivariable relationships were found between MF fat infiltration and MF thickness ratio. Participants with LBP exhibited lower contraction ratios (p = 0.017) and higher SWE during contraction (p = 0.03) at L4/L5 compared to controls. Conclusion: This study highlights a positive association between MF fat infiltration and SWE-based stiffness measures at L4/L5, suggesting altered muscle composition may impacts MF function. However, no relationship was found between MF fat infiltration and contraction. Participants with LBP demonstrated distinct deficits in muscle activation, supporting the need for targeted rehabilitation strategies addressing these functional impairments. |
