Keyword search (4,164 papers available)

"fibrosis" Keyword-tagged Publications:

Title Authors PubMed ID
1 Sex Differences in the Association Between Subjective Social Status and Imaging Markers of Cardiac Inflammation and Fibrosis Sánchez-Carro Y; Moukarzel M; Friedrich MG; Gouin JP; Luu JM; 40471966
PSYCHOLOGY
2 Curcumin inhibition of bleomycin-induced changes in lung collagen synthesis, deposition and assembly Durairaj P; Venkatesan S; Narayanan V; Babu M; 34643929
BIOLOGY
3 How do cystic fibrosis patients experience parenthood? A systematic review Jacob A; Journiac J; Fischer L; Astrologo L; Flahault C; 32431218
PSYCHOLOGY
4 Protective effects of curcumin on bleomycin-induced changes in lung glycoproteins. Durairaj P, Venkatesan S, Narayanan V, Babu M 32350681
BIOLOGY

 

Title:Sex Differences in the Association Between Subjective Social Status and Imaging Markers of Cardiac Inflammation and Fibrosis
Authors:Sánchez-Carro YMoukarzel MFriedrich MGGouin JPLuu JM
Link:https://pubmed.ncbi.nlm.nih.gov/40471966/
DOI:10.1097/PSY.0000000000001411
Publication:Biopsychosocial science and medicine
Keywords:cardiac inflammationcardiovascular diseasefibrosissexsocioeconomic statussubjective social status
PMID:40471966 Category: Date Added:2025-06-05
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montreal, Canada (Sánchez-Carro, Gouin); Department of Medicine and Health Sciences, McGill University, Montreal, Canada (Moukarzel, Friedrich, Luu); Department of Diagnostic Radiology, McGill University, Montreal, Canada (Friedrich).

Description:

Objective: Beyond objective socioeconomic status (SES) indicators, subjective social status (SSS), an individual's subjective perception of their social standing relative to others, has been independently linked to cardiovascular disease (CVD) morbidity and mortality. Some studies also report sex differences in the association between SSS and CVD. This study aimed to investigate these potential sex differences using advanced cardiac magnetic resonance imaging to detect subclinical CVD progression among healthy individuals.

Methods: A cross-sectional study was conducted with 443 participants (mean age=56.40, SD=10.88; 52.14% females) free of CVD. All participants underwent CMR for quantitative assessment of T1 and T2 mapping, reflecting respectively diffuse fibrosis and edema, as part of inflammatory processes in the heart. SSS was measured using the MacArthur Subjective Social Status Scale.

Results: Female sex (b(SE)=0.29 (0.10), P=0.005), lower education (b(SE)=-0.23 (0.10), P=0.026), and an interaction between sex and SSS (b(SE)=-0.15 (0.06), P=0.019) were associated with higher T1 values, indicating a stronger association between lower SSS and cardiac fibrosis markers in females compared to males. No significant associations were found for T2 values.

Conclusions: These findings extend the literature on the association of SSS with cardiovascular outcomes. Compared to males, females demonstrated a stronger association between lower SSS and an imaging marker of cardiac fibrosis among individuals free of CVD, further highlighting the relevance of sex-specific cardiovascular risk assessment.





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