PERFORM Publications

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Title		Authors	PubMed ID
1	Improved electrical performance of PDMS and PEDOT: PSS composites with MWCNT and AgNP particles	Shafagh SH; Deen I; Packirisamy M;	41424586 ENCS
2	Light-Activated Micromotors in Air Propelled by Thermal Convection	Mena-Giraldo P; Mandl GA; Quezada-Novoa V; Garcia-Henao C; Bondon N; Hazlett MJ; Capobianco JA;	40964823 CNSR
3	A synthetic model of bioinspired liposomes to study cancer-cell derived extracellular vesicles and their uptake by recipient cells	López RR; Ben El Khyat CZ; Chen Y; Tsering T; Dickinson K; Bustamante P; Erzingatzian A; Bartolomucci A; Ferrier ST; Douanne N; Mounier C; Stiharu I; Nerguizian V; Burnier JV;	40069225 ENCS
4	Long-lasting antimicrobial effect of multipurpose ZnO nanoparticle-loaded dental resins enhanced by blue light photodynamic therapy	Leite ML; Comeau P; Zaghwan A; Shen Y; Manso AP;	39765362 ENCS
5	3D bioheat transfer mapping reveals nanomagnetic particles effectiveness in radiofrequency hyperthermia breast cancer treatment comparing to experimental study	Kavousi M; Saadatmand E; Masoumbeigi M; Mahdavi R; Riyahi Alam N;	39557504 PHYSICS
6	Non-invasive paper-based sensors containing rare-earth-doped nanoparticles for the detection of D-glucose	López-Peña G; Ortiz-Mansilla E; Arranz A; Bogdan N; Manso-Silván M; Martín Rodríguez E;	38729020 CHEMBIOCHEM
7	Tailoring plasmonic sensing strategies for the rapid and sensitive detection of hypochlorite in swimming water samples	Sadiq Z; Al-Kassawneh M; Safiabadi Tali SH; Jahanshahi-Anbuhi S;	38451315 ENCS
8	Janus Micromotors for Photophoretic Motion and Photon Upconversion Applications Using a Single Near-Infrared Wavelength	Mena-Giraldo P; Kaur M; Maurizio SL; Mandl GA; Capobianco JA;	38197400 CHEMBIOCHEM
9	SiCNFe Ceramics as Soft Magnetic Material for MEMS Magnetic Devices: A Mössbauer Study	Stiharu I; Andronenko S; Zinnatullin A; Vagizov F;	37241549 PHYSICS
10	Gold Nanoparticles-Based Colorimetric Assays for Environmental Monitoring and Food Safety Evaluation	Sadiq Z; Safiabadi Tali SH; Hajimiri H; Al-Kassawneh M; Jahanshahi-Anbuhi S;	36629748 ENCS
11	Utilization of a biosurfactant foam/nanoparticle mixture for treatment of oil pollutants in soil	Vu KA; Mulligan CN;	35834082 ENCS
12	Remediation of oil-contaminated soil using Fe/Cu nanoparticles and biosurfactants	Vu KA; Mulligan CN;	35361056 ENCS
13	Electrospun Upconverting Nanofibrous Hybrids with Smart NIR-Light-Controlled Drug Release for Wound Dressing	Huang HY; Skripka A; Zaroubi L; Findlay BL; Vetrone F; Skinner C; Oh JK; Cuccia LA;	35019380 CHEMBIOCHEM
14	Microfluidic Shear Processing Control of Biological Reduction Stimuli-Responsive Polymer Nanoparticles for Drug Delivery.	Huang Y, Jazani AM, Howell EP, Reynolds LA, Oh JK, Moffitt MG	33455300 CHEMBIOCHEM
15	Using intracellular plasmonics to characterize nanomorphology in human cells.	Sohrabi Kashani A, Piekny A, Packirisamy M	33365137 BIOLOGY
16	Controlled Microfluidic Synthesis of Biological Stimuli-Responsive Polymer Nanoparticles.	Huang Y, Moini Jazani A, Howell EP, Oh JK, Moffitt MG	31820915 CHEMBIOCHEM
17	The Key Role of Intrinsic Lifetime Dynamics from Upconverting Nanosystems in Multiemission Particle Velocimetry	Tessitore G; Maurizio SL; Sabri T; Skinner CD; Capobianco JA;	32924221 CNSR
18	Exploring the biophysicochemical alteration of green alga Asterococcus superbus interactively affected by nanoparticles, triclosan and illumination.	Xin X, Huang G, An C, Lu C, Xiong W	32473326 ENCS
19	Wavelength-Selective Nonlinear Imaging and Photo-Induced Cell Damage by Dielectric Harmonic Nanoparticles.	Kilin V, Campargue G, Fureraj I, Sakong S, Sabri T, Riporto F, Vieren A, Mugnier Y, Mas C, Staedler D, Collins JM, Bonacina L, Vogel A, Capobianco JA, Wolf JP	32282184 CNSR
20	Surface Response Based Modeling of Liposome Characteristics in a Periodic Disturbance Mixer.	López RR, Ocampo I, Sánchez LM, Alazzam A, Bergeron KF, Camacho-León S, Mounier C, Stiharu I, Nerguizian V	32106424 ENCS

Title:	Controlled Microfluidic Synthesis of Biological Stimuli-Responsive Polymer Nanoparticles.
Authors:	Huang Y, Moini Jazani A, Howell EP, Oh JK, Moffitt MG
Link:	https://www.ncbi.nlm.nih.gov/pubmed/31820915
DOI:	10.1021/acsami.9b17101
Publication:	ACS applied materials & interfaces
Keywords:	directed self-assembly; drug delivery; microfluidics; nanoparticles; stimuli-responsive block copolymers;
PMID:	31820915	Category:	ACS Appl Mater Interfaces	Date Added:	2020-09-24
Dept Affiliation:	CHEMBIOCHEM 1 Department of Chemistry , University of Victoria , PO Box 1700 Stn CSC, Victoria , BC V8W 2Y2 Canada. 2 Department of Chemistry and Biochemistry , Concordia University , 7141 Sherbrooke St. West , Montreal , Quebec H4B 1R6 , Canada.

Description:

Controlled Microfluidic Synthesis of Biological Stimuli-Responsive Polymer Nanoparticles.

ACS Appl Mater Interfaces. 2020 Jan 08; 12(1):177-190

Authors: Huang Y, Moini Jazani A, Howell EP, Oh JK, Moffitt MG

Abstract

Microfluidic flow-directed self-assembly of biological stimuli-responsive block copolymers is demonstrated with dual-location cleavable linkages at the junction between hydrophilic and hydrophobic blocks and on pendant group within the hydrophobic blocks. On-chip self-assembly within a two-phase microfluidic reactor forms various "DualM" polymer nanoparticles (PNPs), including cylinders and multicompartment vesicles, with sizes and morphologies that are tunable with manufacturing flow rate. Complex kinetically trapped intermediates between shear-dependent states provide the most detailed mechanism to date of microfluidic PNP formation in the presence of flow-variable high shear. Glutathione (GSH)-triggered changes in PNP size and internal structure depend strongly on the initial flow-directed size and internal structure. Upon incubation in GSH, flow-directed PNPs with smaller average sizes showed a faster hydrodynamic size increase (attributed to junction cleavage) and those with higher excess Gibbs free energy showed faster inner compartment growth (attributed to pendant cleavage). These results demonstrate that the combination of chemical control of the location of biologically responsive linkages with microfluidic shear processing offers promising routes for tunable "smart" polymeric nanomedicines.

PMID: 31820915 [PubMed - indexed for MEDLINE]

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