Keyword search (4,163 papers available)

"neuropsychology" Keyword-tagged Publications:

Title Authors PubMed ID
1 Overcoming boundaries: Interdisciplinary challenges and opportunities in cognitive neuroscience Brignol A; Paas A; Sotelo-Castro L; St-Onge D; Beltrame G; Coffey EBJ; 38750788
PSYCHOLOGY
2 A network approach to subjective cognitive decline: Exploring multivariate relationships in neuropsychological test performance across Alzheimer's disease risk states Grunden N; Phillips NA; ; 38458017
PSYCHOLOGY
3 Post-COVID-19 fatigue: the contribution of cognitive and neuropsychiatric symptoms Calabria M; García-Sánchez C; Grunden N; Pons C; Arroyo JA; Gómez-Anson B; Estévez García MDC; Belvís R; Morollón N; Vera Igual J; Mur I; Pomar V; Domingo P; 35488918
PSYCHOLOGY
4 Neuropsychological deficits in patients with cognitive complaints after COVID-19 García-Sánchez C; Calabria M; Grunden N; Pons C; Arroyo JA; Gómez-Anson B; Lleó A; Alcolea D; Belvís R; Morollón N; Mur I; Pomar V; Domingo P; 35137561
PSYCHOLOGY
5 Evidence of a Relation Between Hippocampal Volume, White Matter Hyperintensities, and Cognition in Subjective Cognitive Decline and Mild Cognitive Impairment Caillaud M; Hudon C; Boller B; Brambati S; Duchesne S; Lorrain D; Gagnon JF; Maltezos S; Mellah S; Phillips N; Belleville S; 31758692
CRDH
6 Brain perfusion during rapid-eye-movement sleep successfully identifies amnestic mild cognitive impairment. Brayet P, Petit D, Baril AA, Gosselin N, Gagnon JF, Soucy JP, Gauthier S, Kergoat MJ, Carrier J, Rouleau I, Montplaisir J 28522082
PERFORM

 

Title:Evidence of a Relation Between Hippocampal Volume, White Matter Hyperintensities, and Cognition in Subjective Cognitive Decline and Mild Cognitive Impairment
Authors:Caillaud MHudon CBoller BBrambati SDuchesne SLorrain DGagnon JFMaltezos SMellah SPhillips NBelleville S
Link:https://pubmed.ncbi.nlm.nih.gov/31758692/
DOI:10.1093/geronb/gbz120
Publication:The journals of gerontology. Series B, Psychological sciences and social sciences
Keywords:Alzheimer's diseaseBiomarkersNeuroimagingNeuropsychology
PMID:31758692 Category:J Gerontol B Psychol Sci Soc Sci Date Added:2019-11-24
Dept Affiliation: CRDH
1 Research Centre, Institut universitaire de gériatrie de Montréal, Québec, Canada.
2 Department of Psychology, Université de Montréal, Québec, Canada.
3 CERVO Brain Research Centre, Institut universitaire en santé mentale de Québec, Canada.
4 Department of Psychology, Université de Laval, Québec, Canada.
5 Departement of Psychology, Université du Québec à Trois-Rivières, Québec, Canada.
6 Department of Radiology, Université de Laval, Québec, Canada.
7 Research Centre, Centre de recherche sur le vieillissement de Sherbrooke, Québec, Canada.
8 Department of Psychology, Université de Sherbrooke, Québec, Canada.
9 Department of Psychology, Université du Québec à Montréal, Québec, Canada.
10 Department of Psychology, Centre for Research in Human Development (CRDH), Concordia University, Montreal, Québec, Canada.

Description:

Objective: The concepts of mild cognitive impairment (MCI) and subjective cognitive decline (SCD) have been proposed to identify individuals in the early stages of Alzheimer's disease (AD), or other neurodegenerative diseases. One approach to validate these concepts is to investigate the relationship between pathological brain markers and cognition in those individuals.

Method: We included 126 participants from the Consortium for the Early Identification of Alzheimer's disease-Quebec (CIMA-Q) cohort (67 SCD, 29 MCI, and 30 cognitively healthy controls [CH]). All participants underwent a complete cognitive assessment and structural magnetic resonance imaging. Group comparisons were done using cognitive data, and then correlated with hippocampal volumes and white matter hyperintensities (WMHs).

Results: Significant differences were found between participants with MCI and CH on episodic and executive tasks, but no differences were found when comparing SCD and CH. Scores on episodic memory tests correlated with hippocampal volumes in both MCI and SCD, whereas performance on executive tests correlated with WMH in all of our groups.

Discussion: As expected, the SCD group was shown to be cognitively healthy on tasks where MCI participants showed impairment. However, SCD's hippocampal volume related to episodic memory performances, and WMH to executive functions. Thus, SCD represents a valid research concept and should be used, alongside MCI, to better understand the preclinical/prodromal phase of AD.





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