PERFORM Publications

Keyword search (4,163 papers available)

Title		Authors	PubMed ID
1	Longitudinal effects of cerebrovascular reactivity and cerebral pulsatility in cognitively intact older adults with APOE4: links with cognition	Potvin-Jutras Z; Tremblay PL; Mohammadi H; Villeneuve S; Spreng RN; Gauthier CJ;	41353310 SOH
2	Neuropsychiatric Symptoms and Psychotropic Medication Use Following SARS-Cov-2 Infection Among Elderly Residents in Long-Term Care Facilities	Cruz-Santiago D; Meng X; Canac-Marquis M; Sengupta A; Brassard JP; Pavey E; Girouard H; Vinh DC; Gouin JP;	40051588 PSYCHOLOGY
3	Realistic dual-task listening-while-balancing in older adults with normal hearing and hearing loss with and without hearing aids	Mohanathas N; Montanari L; Gabriel GA; Downey R; Li KZH; Campos JL;	39567644 PERFORM
4	Vulnerability and narrative in later life	de Medeiros K; Ermoshkina P;	38761242 SOCANTH
5	A Qualitative Evaluation of a Plate-Method Dietary Self-Monitoring Tool in a Sample of Adults Over 50	Bouchaud CC; Chriqui JR; Slim M; Gouin JP; Plourde H; Cohen TR;	37600934 PERFORM
6	Negotiating Experiences of Belonging Alongside Age-Related Life Transitions	Fortune D; Weisgarber B;	37518953 CONCORDIA
7	Correlates and trajectories of loneliness among community-dwelling older adults during the COVID-19 pandemic: A Canadian longitudinal study	Lara E; Matovic S; Vasiliadis HM; Grenier S; Berbiche D; de la Torre-Luque A; Gouin JP;	37499331 PSYCHOLOGY
8	The association between information and communication technologies, loneliness and social connectedness: A scoping review	Petersen B; Khalili-Mahani N; Murphy C; Sawchuk K; Phillips N; Li KZH; Hebblethwaite S;	37034933 PSYCHOLOGY
9	Older adults' perceptions of the risks associated with contemporary gambling environments: Implications for public health policy and practice	Pitt H; McCarthy S; Thomas SL; Randle M; Marko S; Cowlishaw S; Kairouz S; Daube M;	37006633 SOCANTH
10	Trajectories of psychological distress during the COVID-19 pandemic among community-dwelling older adults in Quebec: A longitudinal study	Matovic S; Grenier S; Jauvin F; Gravel C; Vasiliadis HM; Vasil N; Belleville S; Rainville P; Dang-Vu TT; Aubertin-Leheudre M; Knäuper B; Dialahy IZ; Gouin JP;	36703303 HKAP
11	Benefits of a 3-month cycle of weekly virtual museum tours in community dwelling older adults: Results of a randomized controlled trial	Beauchet O; Matskiv J; Galery K; Goossens L; Lafontaine C; Sawchuk K;	36052331 CONCORDIA
12	Comparing the effect of Cognitive vs. Exercise Training on brain MRI outcomes in healthy older adults: A systematic review	Intzandt B; Vrinceanu T; Huck J; Vincent T; Montero-Odasso M; Gauthier CJ; Bherer L;	34245760 PERFORM
13	Resource-rational approach to meta-control problems across the lifespan	Ruel A; Devine S; Eppinger B;	33590729 PERFORM
14	Sex differences in the relationship between dietary pattern adherence and cognitive function among older adults: findings from the NuAge study.	D'Amico D, Parrott MD, Greenwood CE, Ferland G, Gaudreau P, Belleville S, Laurin D, Anderson ND, Kergoat MJ, Morais JA, Presse N, Fiocco AJ,	32563260 PERFORM
15	The Association between Generalized Anxiety Disorder, Subthreshold Anxiety Symptoms and Fear of Falling among Older Adults: Preliminary Results from a Pilot Study.	Payette MC, Bélanger C, Benyebdri F, Filiatrault J, Bherer L, Bertrand JA, Nadeau A, Bruneau MA, Clerc D, Saint-Martin M, Cruz-Santiago D, Ménard C, Nguyen P, Vu TTM, Comte F, Bobeuf F, Grenier S	28452660 PERFORM
16	Specific transfer effects following variable priority dual-task training in older adults.	Lussier M, Bugaiska A, Bherer L	27372514 PERFORM
17	Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults.	Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium	27785698 PERFORM

Title:	Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults.
Authors:	Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium
Link:	https://www.ncbi.nlm.nih.gov/pubmed/27785698?dopt=Abstract
DOI:	10.1007/s10548-016-0533-z
Publication:	Brain topography
Keywords:	Brain volume; Fall; Magnetic resonance imaging; Motor control; Older adults;
PMID:	27785698	Category:	Brain Topogr	Date Added:	2019-04-15
Dept Affiliation:	PERFORM 1 Division of Geriatric Medicine, Department of Medicine, Sir Mortimer B. Davis - Jewish General Hospital and Lady Davis Institute for Medical Research, McGill University, Montreal, QC, Canada. Olivier.beauchet@mcgill.ca. 2 Dr. Joseph Kaufmann Chair in Geriatric Medicine, Faculty of Medicine, McGill University, Montreal, QC, Canada. Olivier.beauchet@mcgill.ca. 3 Centre of Excellence on Aging and Chronic Diseases of McGill Integrated University Health Network, Montreal, QC, Canada. Olivier.beauchet@mcgill.ca. 4 Division of Geriatric Medicine, Department of Neuroscience, Angers University Hospital, Angers, France. 5 University Memory Clinic of Angers, Angers, France. 6 UPRES EA 4638, University of Angers, UNAM, Angers, France. 7 Neuromechanical Research Centre, Faculty of Kinesiology and Health Studies, University of Regina, Regina, SK, Canada. 8 Aging, Mobility and Cognitive Neuroscience Laboratory, Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada. 9 Andrew and Marjorie McCain Human Performance Laboratory, Richard J. Currie Center, Faculty of Kinesiology, University of New Brunswick, Fredericton, NB, Canada. 10 Department of Physical Therapy, College of Rehabilitation Sciences, University of Manitoba, Winnipeg, MB, Canada. 11 Centre de recherche, Institut universitaire de gériatrie de Montréal (CRIUGM), Montréal, QUÉBEC, Canada. 12 Research Center on Aging, Institut universitaire de gériatrie de Sherbrooke (IUGS), Sherbrooke, QUÉBEC, Canada. 13 PERFORM Centre and Department of Psychology, Concordia University, Montreal, QC, Canada. 14 Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway. 15 Division of Cognitive & Motor Aging, Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY, USA. 16 Department of Neurology, Geneva University Hospital and University of Geneva, Geneva, Switzerland.

Description:

Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults.

Brain Topogr. 2017 03;30(2):272-280

Authors: Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G, Biomathics and Canadian Gait Consortium

Abstract

Falls are a consequence of gait instability. Cortical and subcortical abnormalities have been associated with gait instability but not yet with falls. This study aims to compare the global and regional brain subvolumes between healthy older fallers and non-fallers. A total of 77 healthy older individuals (23 fallers and 54 non-fallers, 69.8 ± 3.5 years; 45.5 % female) were included in this study using a cross-sectional design. Based on an a priori hypothesis, the following brain subvolumes were quantified from three-dimensional T1-weighted MRI using FreeSurfer software: total white matter abnormalities, total white matter, total cortical and subcortical gray matter, hippocampus, motor cortex, somatosensory cortex, premotor cortex, prefrontal cortex and parietal cortex volumes. Gait performances were also recorded. Age, sex, body mass index, comorbidities, use of psychoactive drugs, far-distance visual acuity, lower-limb proprioception, depressive symptoms and cognitive scores (Mini-Mental State Examination, Frontal Assessment Battery) were used as covariates. Fallers have more frequently depressive symptoms (P = 0.048), a lower far distance visual acuity (P = 0.026) and a higher coefficient of variation of stride time (P = 0.008) compared to non-fallers. There was a trend to greater subvolumes for the somatosensory cortex (P = 0.093) and the hippocampus (P = 0.060) in the falls group. Multiple logistic regressions showed that subvolumes of the somatosensory cortex and the hippocampus (P < 0.042) were increased in fallers compared to non-fallers, even after adjustment for clinical and brain characteristics. The greater subvolumes of the somatosensory cortex and hippocampus reported in fallers compared to non-fallers suggests a possible brain compensatory mechanism involving spatial navigation and integration of sensory information.

PMID: 27785698 [PubMed - indexed for MEDLINE]

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