Keyword search (4,164 papers available)

"orbitofrontal" Keyword-tagged Publications:

Title Authors PubMed ID
1 OFC neurons do not represent the negative value of a conditioned inhibitor Esber GR; Usypchuk A; Saini S; Deroche M; Iordanova MD; Schoenbaum G; 38042330
CONCORDIA
2 Calcium activity is a degraded estimate of spikes Hart EE; Gardner MPH; Panayi MC; Kahnt T; Schoenbaum G; 36368324
PSYCHOLOGY
3 Mechanisms of higher-order learning in the amygdala Gostolupce D; Iordanova MD; Lay BPP; 34197867
PSYCHOLOGY
4 Different methods of fear reduction are supported by distinct cortical substrates. Lay BP, Pitaru AA, Boulianne N, Esber GR, Iordanova MD 32589138
PSYCHOLOGY

 

Title:Mechanisms of higher-order learning in the amygdala
Authors:Gostolupce DIordanova MDLay BPP
Link:https://pubmed.ncbi.nlm.nih.gov/34197867/
DOI:10.1016/j.bbr.2021.113435
Publication:Behavioural brain research
Keywords:Fear conditioningLearningOrbitofrontal cortexPerirhinal cortexRetrosplenial cortexSecond-order conditioningSensory preconditioning
PMID:34197867 Category: Date Added:2021-07-02
Dept Affiliation: PSYCHOLOGY
1 Center for Studies in Behavioural Neurobiology, Department of Psychology, Concordia University, Montreal, QC, Canada.
2 Center for Studies in Behavioural Neurobiology, Department of Psychology, Concordia University, Montreal, QC, Canada. Electronic address: mihaela.iordanova@concordia.ca.

Description:

Adaptive behaviour is under the potent control of environmental cues. Such cues can acquire value by virtue of their associations with outcomes of motivational significance, be they appetitive or aversive. There are at least two ways through which an environmental cue can acquire value, through first-order and higher-order conditioning. In first-order conditioning, a neutral cue is directly paired with an outcome of motivational significance. In higher-order conditioning, a cue is indirectly associated with motivational events via a directly conditioned first-order stimulus. The present article reviews some of the associations that support learning in first- and higher-order conditioning, as well as the role of the BLA and the molecular mechanisms involved in these two types of learning.





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