PERFORM Publications

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Title		Authors	PubMed ID
1	Imagining the beat: causal evidence for dorsal premotor cortex (dPMC) role in beat imagery via transcranial magnetic stimulation (TMS)	Lazzari G; Ferreri L; Cattaneo L; Penhune V; Lega C;	41248776 PSYCHOLOGY
2	Assessing in silico tools for accurate pathogenicity prediction in CHD nucleosome remodelers	Rabouhi N; Guindon S; Coleman EA; van Heesbeen HJ; Greenwood CMT; Lu T; Campeau PM;	40907936 ENCS
3	Application of machine learning for predicting the incubation period of water droplet erosion in metals	AlHammad K; Medraj M; Tembely M;	40612685 ENCS
4	Rubber Fatigue Revisited: A State-of-the-Art Review Expanding on Prior Works by Tee, Mars and Fatemi	Wang X; Sedaghati R; Rakheja S; Shangguan W;	40219307 ENCS
5	Perceptions of carbon dioxide emission reductions and future warming among climate experts	Wynes S; Davis SJ; Dickau M; Ly S; Maibach E; Rogelj J; Zickfeld K; Matthews HD;	39280638 CONCORDIA
6	Brain tumor detection based on a novel and high-quality prediction of the tumor pixel distributions	Sun Y; Wang C;	38493601 ENCS
7	Development and validation of risk of CPS decline (RCD): a new prediction tool for worsening cognitive performance among home care clients in Canada	Guthrie DM; Williams N; O' Rourke HM; Orange JB; Phillips N; Pichora-Fuller MK; Savundranayagam MY; Sutradhar R;	38041046 CRDH
8	Context changes judgments of liking and predictability for melodies	Albury AW; Bianco R; Gold BP; Penhune VB;	38034280 PSYCHOLOGY
9	NMDA Receptors in the Basolateral Amygdala Complex Are Engaged for Pavlovian Fear Conditioning When an Animal's Predictions about Danger Are in Error	Tuval Keidar	37607821 CSBN
10	Deep learning approach to security enforcement in cloud workflow orchestration	El-Kassabi HT; Serhani MA; Masud MM; Shuaib K; Khalil K;	36691661 ENCS
11	Calcium activity is a degraded estimate of spikes	Hart EE; Gardner MPH; Panayi MC; Kahnt T; Schoenbaum G;	36368324 PSYCHOLOGY
12	Weakly Supervised Occupancy Prediction Using Training Data Collected via Interactive Learning	Bouhamed O; Amayri M; Bouguila N;	35590880 ENCS
13	Prediction error determines whether NMDA receptors in the basolateral amygdala complex are involved in Pavlovian fear conditioning	Williams-Spooner MJ; Delaney AJ; Westbrook RF; Holmes NM;	35410880 PSYCHOLOGY
14	Towards a better understanding of deep convolutional neural network processes for recognizing organic chemicals of environmental concern	Sun X; Zhang X; Wang L; Li Y; Muir DCG; Zeng EY;	34388923 CHEMBIOCHEM
15	Arcuate fasciculus architecture is associated with individual differences in pre-attentive detection of unpredicted music changes	Vaquero L; Ramos-Escobar N; Cucurell D; François C; Putkinen V; Segura E; Huotilainen M; Penhune V; Rodríguez-Fornells A;	33454403 MLNP
16	Integrative approach for detecting membrane proteins.	Alballa M, Butler G	33349234 CSFG
17	Inter-protein residue covariation information unravels physically interacting protein dimers	Salmanian S; Pezeshk H; Sadeghi M;	33334319 ENCS
18	CCCDTD5 recommendations on early non cognitive markers of dementia: A Canadian consensus	Montero-Odasso M; Pieruccini-Faria F; Ismail Z; Li K; Lim A; Phillips N; Kamkar N; Sarquis-Adamson Y; Speechley M; Theou O; Verghese J; Wallace L; Camicioli R;	33094146 CRDH
19	Prediction Errors in Depression: A Quasi-Experimental Analysis.	Radomsky AS, Wong SF, Dussault D, Gilchrist PT, Tesolin SB	32746394 PSYCHOLOGY
20	TooT-T: discrimination of transport proteins from non-transport proteins.	Alballa M, Butler G	32321420 CSFG
21	Water Droplet Erosion of Wind Turbine Blades: Mechanics, Testing, Modeling and Future Perspectives.	Elhadi Ibrahim M, Medraj M	31906204 ENCS
22	Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.	Mendoza JA, Lafferty CK, Yang AK, Britt JP	31693885 CSBN
23	Genotype scores predict drug efficacy in subtypes of female sexual interest/arousal disorder: A double-blind, randomized, placebo-controlled cross-over trial.	Tuiten A, Michiels F, Böcker KB, Höhle D, van Honk J, de Lange RP, van Rooij K, Kessels R, Bloemers J, Gerritsen J, Janssen P, de Leede L, Meyer JJ, Everaerd W, Frijlink HW, Koppeschaar HP, Olivier B, Pfaus JG	30016917 CSBN
24	Evaluating Programs for Predicting Genes and Transcripts with RNA-Seq Support in Fungal Genomes.	Reid I	29876820 CSFG

Title:	Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.
Authors:	Mendoza JA, Lafferty CK, Yang AK, Britt JP
Link:	https://www.ncbi.nlm.nih.gov/pubmed/31693885?dopt=Abstract
DOI:	10.1016/j.celrep.2019.09.077
Publication:	Cell reports
Keywords:	calcium imaging; dopamine; expected value; motivation; optogenetics; overexpectation; reinforcement learning; reward prediction error; ventral tegmental area;
PMID:	31693885	Category:	Cell Rep	Date Added:	2019-11-07
Dept Affiliation:	CSBN 1 Department of Psychology, McGill University, Montreal, QC H3A 1B1, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada. 2 Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada. 3 Department of Psychology, McGill University, Montreal, QC H3A 1B1, Canada; Integrated Program in Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada; Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, QC H4B 1R6, Canada. Electronic address: jonathan.britt@mcgill.ca.

Description:

Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value.

Cell Rep. 2019 Nov 05;29(6):1429-1437.e3

Authors: Mendoza JA, Lafferty CK, Yang AK, Britt JP

Abstract

Cue-evoked midbrain dopamine (DA) neuron activity reflects expected value, but its influence on reward assessment is unclear. In mice performing a trial-based operant task, we test if bidirectional manipulations of cue or operant-associated DA neuron activity drive learning as a result of under- or overexpectation of reward value. We target optogenetic manipulations to different components of forced trials, when only one lever is presented, and assess lever biases on choice trials in the absence of photomanipulation. Although lever biases are demonstrated to be flexible and sensitive to changes in expected value, augmentation of cue or operant-associated DA signaling does not significantly alter choice behavior, and blunting DA signaling during any component of the forced trials reduces choice trial responses on the associated lever. These data suggest cue-evoked DA helps maintain cue-value associations but does not encode expected value as to set the benchmark against which received reward is judged.

PMID: 31693885 [PubMed - in process]

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