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PubMed Publications| Keyword search (4,163 papers available) |  |
"rats" Keyword-tagged Publications:
| Title | Authors | PubMed ID | |
|---|---|---|---|
| 1 | Modeling hormonal contraception in female rats: a framework for studies in behavioral neurobiology | Lacasse JM; Gomez-Perales E; Brake WG; | 35952797 PSYCHOLOGY |
| 2 | Supplementary dataset of context-dependent conditioned responding to an alcohol-predictive cue in female and male rats | Segal D; Valyear MD; Chaudhri N; | 35330738 PSYCHOLOGY |
| 3 | Dexamethasone-Induced Perturbations in Tissue Metabolomics Revealed by Chemical Isotope Labeling LC-MS analysis | Dahabiyeh LA; Malkawi AK; Wang X; Colak D; Mujamammi AH; Sabi EM; Li L; Dasouki M; Abdel Rahman AM; | 31973046 CHEMBIOCHEM |
| 4 | Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner. | Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A | 29080670 CSBN |
| Title: | Modeling hormonal contraception in female rats: a framework for studies in behavioral neurobiology | ||||
| Authors: | Lacasse JM, Gomez-Perales E, Brake WG | ||||
| Link: | https://pubmed.ncbi.nlm.nih.gov/35952797/ | ||||
| DOI: | 10.1016/j.yfrne.2022.101020 | ||||
| Publication: | Frontiers in neuroendocrinology | ||||
| Keywords: | Animal models; Dose; Ethinyl estradiol; Female rats; Hormonal contraceptives; Levonorgestrel; Methodology; Progestin; | ||||
| PMID: | 35952797 | Category: | Date Added: | 2022-08-12 | |
| Dept Affiliation: |
PSYCHOLOGY
1 Centre for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, Canada, H4B 1R6. Electronic address: lacasse.jesse@gmail.com. 2 Centre for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, Canada, H4B 1R6. 3 Centre for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, Canada, H4B 1R6. Electronic address: wayne.brake@concordia.ca. |
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Description: |
Research on hormonal contraceptives (HC) in animal models is lacking, and as a result, so is our understanding of the impact of HC on the brain and behavior. Here, we provide a review of the pharmacology of HC, as well as the methodology and best practices for designing a model of HC in female rats. We outline specific methodological considerations regarding dosing, route of administration, exposure time/timing, and selecting a control group. We also provide a framework outlining important levels of analysis for thinking about the impact of HC on behavioral and neurobiological outcomes. The purpose of this review is to equip researchers with foundational knowledge, and some basic elements of experimental design for future studies investigating the impact of HC on the brain and behavior of female rats. |
