Keyword search (4,164 papers available)

"regulation" Keyword-tagged Publications:

Title Authors PubMed ID
1 Exploiting fluctuations in gene expression to detect causal interactions between genes Joly-Smith E; Talpur MM; Allard P; Papazotos F; Potvin-Trottier L; Hilfinger A; 41401079
BIOLOGY
2 Child and marital stress are associated with a psychophysiological index of self-regulatory capacities among parents of preschool children MacNeil S; da Estrela C; Caldwell W; Gouin JP; 40972822
PERFORM
3 Global survey of secondary metabolism in em Aspergillus niger /em via activation of specific transcription factors Semper C; Pham TTM; Ram S; Palys S; Evdokias G; Ouedraogo JP; Moisan MC; Geoffrion N; Reid I; Di Falco M; Bailey Z; Tsang A; Benoit-Gelber I; Savchenko A; 40852424
GENOMICS
4 Protecting shorelines in Canadian Indigenous communities: Environmental challenges, policy interventions, and mitigation technologies Iravani R; Biagi M; Laforest S; Lee K; Isaacman L; Chen Z; An C; 40554913
ENCS
5 Identification and comprehensive characterization of moral disapproval and behavioral dysregulation-based pornography-use profiles across 42 countries Bothe B; Tóth-Király I; Popova N; Nagy L; Koós M; Demetrovics Z; Potenza MN; Kraus SW; Ballester-Arnal R; Batthyány D; Bergeron S; Billieux J; Briken P; Burkauskas J; Cárdenas-López G; Carvalho J; Castro-Calvo J; Chen L; Ciocca G; Corazza O; Csako RI; Czakó A; Fernandez DP; Fernandez EF; Fujiwara H; Fuss J; Gabrhelík R; Gewirtz-Meydan A; Gjoneska B; Gola M; Hashim HT; Islam MS; Ismail M; Jiménez-Martínez MC; Jurin T; Kalina O; Klein V; Költo A; Lee CT; Lee SK; Lewczuk K; Lin CY; Lochner C; López-Alvarado S; Lukavská K; Mayta-Tristán P; Miller DJ; Orosová O; Orosz G; Ponce FP; Quintana GR; Quintero Garzola GC; Ramos-Diaz J; Rigaud K; Rousseau A; Scanavino MT; Schulmeyer MK; Sharan P; Shibata M; Shoib S; Sigre-Leirós V; Sniewski L; Spasovski O; Steibliene V; Stein DJ; Štulhofer A; Ünsal BC; Vaillancourt-Morel MP; Van Hout MC; Grubbs JB; 39945767
PSYCHOLOGY
6 Oil spills in coastal regions of the Arctic and Subarctic: Environmental impacts, response tactics, and preparedness Bi H; Wang Z; Yue R; Sui J; Mulligan CN; Lee K; Pegau S; Chen Z; An C; 39689468
ENCS
7 Fe/GMP functional nanomaterial enhancing the denitrification efficiency by bi-signal regulation: Electron transfer and microbial community Hao Y; Guo T; Li H; Liu W; Chen Z; Zhang W; Wang X; Guo J; 39326537
ENCS
8 Who Should Decide How Machines Make Morally Laden Decisions? Dominic Martin 27905083
JMSB
9 Gambling Patterns and Problems of Gamblers on Licensed and Unlicensed Sites in France Costes JM; Kairouz S; Eroukmanoff V; Monson E; 25862019
SOCANTH
10 A cross-cultural comparison of population gambling patterns and regulatory frameworks: France and Québec Kairouz S; Paradis C; Nadeau L; Tovar ML; Pousset M; 27171860
SOCANTH
11 Identification of a Conserved Transcriptional Activator-Repressor Module Controlling the Expression of Genes Involved in Tannic Acid Degradation and Gallic Acid Utilization in Aspergillus niger Arentshorst M; Falco MD; Moisan MC; Reid ID; Spaapen TOM; van Dam J; Demirci E; Powlowski J; Punt PJ; Tsang A; Ram AFJ; 37744122
CSFG
12 Utilization of ferulic acid in Aspergillus niger requires the transcription factor FarA and a newly identified Far-like protein (FarD) that lacks the canonical Zn(II)2Cys6 domain Arentshorst M; Reijngoud J; van Tol DJC; Reid ID; Arendsen Y; Pel HJ; van Peij NNME; Visser J; Punt PJ; Tsang A; Ram AFJ; 37746181
CSFG
13 Understanding National Nonprofit Data Environments Bloodgood EA; Bourns J; Lenczner M; Shibaike T; Tabet J; Melvin A; Wong WH; 36974198
CONCORDIA
14 Specificity of Affective Responses in Misophonia Depends on Trigger Identification Savard MA; Sares AG; Coffey EBJ; Deroche MLD; 35692416
PSYCHOLOGY
15 Understanding the Needs of Primary School Teachers in Supporting Their Students' Emotion Regulation Petrovic J; Mettler J; Argento A; Carsley D; Bloom E; Sullivan S; Heath NL; 35578767
PSYCHOLOGY
16 Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database Rurak GM; Simard S; Freitas-Andrade M; Lacoste B; Charih F; Van Geel A; Stead J; Woodside B; Green JR; Coppola G; Salmaso N; 35108542
ENCS
17 Implicit theories of emotion and mental health during adolescence: the mediating role of emotion regulation. De France K, Hollenstein T 32893732
PSYCHOLOGY
18 Examining the effect of a brief psychoeducation intervention based on self-regulation model on sexual satisfaction for women with breast cancer: A randomized controlled trial Abedini M; Olfati F; Oveisi S; Bahrami N; Astrologo L; Chan YH; 32526688
PSYCHOLOGY
19 Poor inhibition of personally-relevant facial expressions of sadness and anger predicts an elevated cortisol response following awakening six months later. Wong SF, Trespalacios F, Ellenbogen MA 32057777
PSYCHOLOGY
20 Metabolic networks of the human gut microbiota. Selber-Hnatiw S, Sultana T, Tse W, Abdollahi N, Abdullah S, Al Rahbani J, Alazar D, Alrumhein NJ, Aprikian S, Arshad R, Azuelos JD, Bernadotte D, Beswick N, Chazbey H, Church K, Ciubotaru E, D'Amato L, Del Corpo T, Deng J, Di Giulio BL, Diveeva D, Elahie E, Frank JGM, Furze E, Garner R, Gibbs V, Goldberg-Hall R, Goldman CJ, Goltsios FF, Gorjipour K, Grant T, Greco B, Guliyev N, Habrich A, Hyland H, Ibrahim N, Iozzo T, Jawaheer-Fenaoui A, Jaworski JJ, Jhajj MK, Jones J, Joyette R, Kaudeer S, Kelley S, Ki 31799915
BIOLOGY
21 MAP: A Personalized Receptive Music Therapy Intervention to Improve the Affective Well-being of Youths Hospitalized in a Mental Health Unit. Archambault K, Vaugon K, Deumié V, Brault M, Perez RM, Peyrin J, Vaillancourt G, Garel P 31742643
CONCORDIA
22 Population variation in density-dependent growth, mortality and their trade-off in a stream fish. Matte JM, Fraser DJ, Grant JWA 31642512
BIOLOGY
23 Life after breast cancer: moving on, sitting down or standing still? A prospective study of Canadian breast cancer survivors. Sabiston CM, Wrosch C, Fong AJ, Brunet J, Gaudreau P, O'Loughlin J, Meterissian S 30056387
PSYCHOLOGY
24 Glucose-mediated repression of plant biomass utilization in the white-rot fungus Dichomitus squalens. Daly P, Peng M, Di Falco M, Lipzen A, Wang M, Ng V, Grigoriev IV, Tsang A, Mäkelä MR, de Vries RP 31585998
CSFG
25 Agency and Motivation in Adulthood and Old Age. Heckhausen J, Wrosch C, Schulz R 30110574
PSYCHOLOGY
26 Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans. Scaduto CM, Kabrawala S, Thomson GJ, Scheving W, Ly A, Anderson MZ, Whiteway M, Bennett RJ 29255038
BIOLOGY
27 Some Metabolites Act as Second Messengers in Yeast Chronological Aging. Mohammad K, Dakik P, Medkour Y, McAuley M, Mitrofanova D, Titorenko VI 29543708
BIOLOGY
28 The evolutionary rewiring of the ribosomal protein transcription pathway modifies the interaction of transcription factor heteromer Ifh1-Fhl1 (interacts with forkhead 1-forkhead-like 1) with the DNA-binding specificity element. Mallick J, Whiteway M 23625919
BIOLOGY
29 An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger. Niu J, Alazi E, Reid ID, Arentshorst M, Punt PJ, Visser J, Tsang A, Ram AF 28049705
CSFG
30 The pathway intermediate 2-keto-3-deoxy-L-galactonate mediates the induction of genes involved in D-galacturonic acid utilization in Aspergillus niger. Alazi E, Khosravi C, Homan TG, du Pré S, Arentshorst M, Di Falco M, Pham TTM, Peng M, Aguilar-Pontes MV, Visser J, Tsang A, de Vries RP, Ram AFJ 28417461
CSFG

 

Title:An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger.
Authors:Niu JAlazi EReid IDArentshorst MPunt PJVisser JTsang ARam AF
Link:https://www.ncbi.nlm.nih.gov/pubmed/28049705?dopt=Abstract
DOI:10.1534/genetics.116.194050
Publication:Genetics
Keywords:galacturonic acidgene regulationgenomicspectinrepressor proteintranscriptomics
PMID:28049705 Category:Genetics Date Added:2019-06-07
Dept Affiliation: CSFG
1 Molecular Microbiology and Biotechnology, Leiden University, Institute of Biology Leiden, 2333 BE Leiden, The Netherlands.
2 Centre for Structural and Functional Genomics, Concordia University, Montreal, Quebec H4B1R6, Canada.
3 Dutch DNA Biotech, 3704 HE Zeist, Utrecht, The Netherlands.
4 Molecular Microbiology and Biotechnology, Leiden University, Institute of Biology Leiden, 2333 BE Leiden, The Netherlands a.f.j.ram@biology.leidenuniv.nl.

Description:

An Evolutionarily Conserved Transcriptional Activator-Repressor Module Controls Expression of Genes for D-Galacturonic Acid Utilization in Aspergillus niger.

Genetics. 2017 01;205(1):169-183

Authors: Niu J, Alazi E, Reid ID, Arentshorst M, Punt PJ, Visser J, Tsang A, Ram AF

Abstract

The expression of genes encoding extracellular polymer-degrading enzymes and the metabolic pathways required for carbon utilization in fungi are tightly controlled. The control is mediated by transcription factors that are activated by the presence of specific inducers, which are often monomers or monomeric derivatives of the polymers. A D-galacturonic acid-specific transcription factor named GaaR was recently identified and shown to be an activator for the expression of genes involved in galacturonic acid utilization in Botrytis cinerea and Aspergillus niger Using a forward genetic screen, we isolated A. niger mutants that constitutively express GaaR-controlled genes. Reasoning that mutations in the gaaR gene would lead to a constitutively activated transcription factor, the gaaR gene in 11 of the constitutive mutants was sequenced, but no mutations in gaaR were found. Full genome sequencing of five constitutive mutants revealed allelic mutations in one particular gene encoding a previously uncharacterized protein (NRRL3_08194). The protein encoded by NRRL3_08194 shows homology to the repressor of the quinate utilization pathway identified previously in Neurospora crassa (qa-1S) and Aspergillus nidulans (QutR). Deletion of NRRL3_08194 in combination with RNA-seq analysis showed that the NRRL3_08194 deletion mutant constitutively expresses genes involved in galacturonic acid utilization. Interestingly, NRRL3_08194 is located next to gaaR (NRRL3_08195) in the genome. The homology to the quinate repressor, the chromosomal clustering, and the constitutive phenotype of the isolated mutants suggest that NRRL3_08194 is likely to encode a repressor, which we name GaaX. The GaaR-GaaX module and its chromosomal organization is conserved among ascomycetes filamentous fungi, resembling the quinate utilization activator-repressor module in amino acid sequence and chromosomal organization.

PMID: 28049705 [PubMed - indexed for MEDLINE]





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