Keyword search (4,164 papers available)

"structure" Keyword-tagged Publications:

Title Authors PubMed ID
1 Land-use history causes differences in park nighttime cooling capacity and forest structure Richmond IC; Paulauskas MA; Padvaiskas E; Gonzàlez Sinisterra LC; Hutt-Taylor K; Robitaille AL; Ziter CD; 40761092
BIOLOGY
2 Variations in perfusion detectable in advance of microstructure in white matter aging Robinson TD; Sun YL; Chang PTH; Gauthier CJ; Chen JJ; 40694306
PHYSICS
3 Evolution from the physical process-based approaches to machine learning approaches to predicting urban floods: a literature review Md Shike Bin Mazid Anik 40692624
ENCS
4 Leveraging deep learning for nonlinear shape representation in anatomically parameterized statistical shape models Gheflati B; Mirzaei M; Rottoo S; Rivaz H; 39953355
ENCS
5 Research Trends in the Development of Block Copolymer-Based Biosensing Platforms Chung YH; Oh JK; 39590001
CHEMBIOCHEM
6 Examining Dimensionality and Item-Quality of the Eating Disorder Examination Questionnaire in Individuals With Eating Disorders Using Item Response Theory Analysis Dufour R; Steiger H; Booij L; 39548958
PSYCHOLOGY
7 Amorphous Cu/Fe nanoparticles with tandem intracellular and extracellular electron capacity for enhancing denitrification performance and recovery of co-contaminant suppressed denitrification Fu J; Guo T; Li H; Liu W; Chen Z; Wang X; Guo J; 39542060
ENCS
8 Crystal structure and Hirshfeld surface analysis of tri-chlorido-(1,10-phenanthroline-κ2 N,N')phenyltin(IV) Benlatreche T; Bensegueni MA; Dénès G; Golhen S; Merazig H; 39372187
CHEMBIOCHEM
9 Music reward sensitivity is associated with greater information transfer capacity within dorsal and motor white matter networks in musicians Matthews TE; Lumaca M; Witek MAG; Penhune VB; Vuust P; 39052097
PSYCHOLOGY
10 Functional and structural characterization of an IclR family transcription factor for the development of dicarboxylic acid biosensors Pham C; Nasr MA; Skarina T; Di Leo R; Kwan DH; Martin VJJ; Stogios PJ; Mahadevan R; Savchenko A; 38696354
BIOLOGY
11 Web-based processing of physiological noise in fMRI: addition of the PhysIO toolbox to CBRAIN Valevicius D; Beck N; Kasper L; Boroday S; Bayer J; Rioux P; Caron B; Adalat R; Evans AC; Khalili-Mahani N; 37841811
ENCS
12 Multi-objective control optimization of isolated bridge using replicator controller and NSGA-II Momeni Z; Bagchi A; 37662735
ENCS
13 Electric Field-Induced Nano-Assembly Formation: First Evidence of Silicon Superclusters with a Giant Permanent Dipole Moment Jardali F; Tran J; Liège F; Florea I; Leulmi ME; Vach H; 37570492
CERMM
14 Understanding the impact of radical changes in diet and the gut microbiota on brain function and structure: rationale and design of the EMBRACE study Ben-Porat T; Alberga A; Audet MC; Belleville S; Cohen TR; Garneau PY; Lavoie KL; Marion P; Mellah S; Pescarus R; Rahme E; Santosa S; Studer AS; Vuckovic D; Woods R; Yousefi R; Bacon SL; 37088645
PERFORM
15 Analysis of an Adaptive Periodic Low-Frequency Wave Filter Featuring Magnetorheological Elastomers Jafari H; Sedaghati R; 36772034
ENCS
16 Structural brain network topological alterations in stuttering adults Gracco VL; Sares AG; Koirala N; 35368614
PSYCHOLOGY
17 Joint intergroup aggression in female colobus monkeys (Colobus vellerosus) is associated with grooming bonds, male participation, and group size Wikberg EC; Gonzalez S; Rodriguez C; Sicotte P; 34927751
BIOLOGY
18 Analyses of microstructural variation in the human striatum using non-negative matrix factorization Robert C; Patel R; Blostein N; Steele CC; Mallar Chakravarty M; 34848302
PSYCHOLOGY
19 Analysis and Design of Lattice Structures for Rapid-Investment Casting Christopher T Richard 34500961
ENCS
20 Numerical assessment of directional energy performance for 3D printed midsole structures Sultana A; Kwok TH; Hsu CC; Ng HD; 34198446
ENCS
21 Characterizing white matter alterations subject to clinical laterality in drug-naïve de novo Parkinson's disease Xiao Y; Peters TM; Khan AR; 34106502
PERFORM
22 Beyond ribose and phosphate: Selected nucleic acid modifications for structure-function investigations and therapeutic applications Liczner C; Duke K; Juneau G; Egli M; Wilds CJ; 33981365
CHEMBIOCHEM
23 The effect of step-feeding distribution ratio on high concentration perchlorate removal performance in ABR system with heterotrophic combined sulfur autotrophic process. Li H, Li K, Guo J, Chen Z, Han Y, Song Y, Lu C, Hou Y, Zhang D, Zhang Y 33485237
ENCS
24 Depression prevalence based on the Edinburgh Postnatal Depression Scale compared to Structured Clinical Interview for DSM DIsorders classification: Systematic review and individual participant data meta-analysis Lyubenova A; Neupane D; Levis B; Wu Y; Sun Y; He C; Krishnan A; Bhandari PM; Negeri Z; Imran M; Rice DB; Azar M; Chiovitti MJ; Saadat N; Riehm KE; Boruff JT; Ioannidis JPA; Cuijpers P; Gilbody S; Kloda LA; Patten SB; Shrier I; Ziegelstein RC; Comeau L; Mitchell ND; Tonelli M; Vigod SN; Aceti F; Barnes J; Bavle AD; Beck CT; Bindt C; Boyce PM; Bunevicius A; Chaudron LH; Favez N; Figueiredo B; Garcia-Esteve L; Giardinelli L; Helle N; Howard LM; Kohlhoff J; Kusminskas L; Kozinszky Z; Lelli L; Leonardou AA; Meuti V; Radoš SN; García PN; Pawlby SJ; Quispel C; Robertson-Blackmore E; Rochat TJ; Sharp DJ; Siu BWM; Stein A; Stewart RC; Tadinac M; Tandon SD; Tendais I; Töreki A; Torres-Giménez A; Tran TD; Trevillion K; Turner K; Vega-Dienstmaier JM; Benedetti A; Thombs BD; 33089942
CONCORDIA
25 Synthesis, crystal structure and Hirshfeld surface of bis-(2-amino-pyridinium) hexa-chlorido-stannate(IV). Ghallab R, Boutebdja M, Dénès G, Merazig H 32844014
CHEMBIOCHEM
26 Computer-Aided Design of Active Pseudoknotted Hammerhead Ribozymes. Najeh S, Zandi K, Djerroud S, Kharma N, Perreault J 32712917
ENCS
27 Influence of Homogenization and Solution Treatments Time on the Microstructure and Hardness of Inconel 718 Fabricated by Laser Powder Bed Fusion Process. Fayed EM, Shahriari D, Saadati M, Brailovski V, Jahazi M, Medraj M 32516909
ENCS
28 DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents. Chiarella J, Schumann L, Pomares FB, Frodl T, Tozzi L, Nemoda Z, Yu P, Szyf M, Khalid-Khan S, Booij L 32479312
PSYCHOLOGY
29 Understanding behavioural engagement and achievement: The roles of teaching practices and student sense of competence and task value. Olivier E, Galand B, Hospel V, Dellisse S 31999841
PSYCHOLOGY
30 Investigating microstructural variation in the human hippocampus using non-negative matrix factorization. Patel R, Steele CJ, Chen A, Patel S, Devenyi GA, Germann J, Tardif CL, Chakravarty MM 31715254
PSYCHOLOGY
31 Cyberinfrastructure for Open Science at the Montreal Neurological Institute. Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C, Durcan TM, Campbell T, Moreau J, Dagher A, Collins DL, Karamchandani J, Bar-Or A, Fon EA, Hoge R, Baillet S, Rouleau G, Evans AC 28111547
IMAGING
32 Crystal structure of poly[di-aqua-(μ-2-carb-oxy-acetato-κ(3) O,O':O'')(2-carb-oxy-acetato-κO)di-μ-chlorido-dicobalt(II)]. Bouaoud Y, Setifi Z, Buvailo A, Potaskalov VA, Merazig H, Dénés G 26870577
CHEMBIOCHEM
33 BioMiCo: a supervised Bayesian model for inference of microbial community structure. Shafiei M, Dunn KA, Boon E, MacDonald SM, Walsh DA, Gu H, Bielawski JP 25774293
BIOLOGY
34 Diversity from genes to ecosystems: A unifying framework to study variation across biological metrics and scales. Gaggiotti OE, Chao A, Peres-Neto P, Chiu CH, Edwards C, Fortin MJ, Jost L, Richards CM, Selkoe KA 30026805
BIOLOGY
35 Genetic structure and diversity of indigenous rice (Oryza sativa) varieties in the Eastern Himalayan region of Northeast India. Choudhury B, Khan ML, Dayanandan S 23741655
BIOLOGY
36 An Adaptive Defect Weighted Sampling Algorithm to Design Pseudoknotted RNA Secondary Structures. Zandi K, Butler G, Kharma N 27499762
CSFG

 

Title:DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents.
Authors:Chiarella JSchumann LPomares FBFrodl TTozzi LNemoda ZYu PSzyf MKhalid-Khan SBooij L
Link:https://www.ncbi.nlm.nih.gov/pubmed/32479312?dopt=Abstract
DOI:10.1016/j.jad.2020.03.062
Publication:Journal of affective disorders
Keywords:Adolescent depressionBrain structureDNA methylationEpigeneticsFunctional connectivity
PMID:32479312 Category:J Affect Disord Date Added:2020-06-02
Dept Affiliation: PSYCHOLOGY
1 Department of Psychology, Concordia University, Montreal, Canada; CHU Sainte-Justine Hospital Research Centre, University of Montreal, Montreal, Canada; Department of Psychology, Queen's University, Kingston, Canada.
2 Department of Psychology, Queen's University, Kingston, Canada.
3 Department of Psychology, Concordia University, Montreal, Canada.
4 Department of Psychiatry and Psychotherapy, Otto von Guericke University, Magdeburg, Germany.
5 Department of Psychiatry, Trinity College School of Medicine and Trinity College Institute of Neuroscience, Dublin, Ireland.
6 Department of Psychology, Concordia University, Montreal, Canada; Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada; Department of Medical Chemistry, Molecular Biology and Pathobiochemistry, Semmelweis University, Budapest, Hungary.
7 Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada.
8 Department of Psychiatry, Division of Child Psychiatry, Hotel Dieu Hospital, Queen's University, Kingston, Canada.
9 Department of Psychology, Concordia University, Montreal, Canada; CHU Sainte-Justine Hospital Research Centre, University of Montreal, Montreal, Canada; Department of Psychology, Queen's University, Kingston, Canada. Electronic address: linda.booij@concordia.ca.

Description:

DNA methylation differences in stress-related genes, functional connectivity and gray matter volume in depressed and healthy adolescents.

J Affect Disord. 2020 Jun 15;271:160-168

Authors: Chiarella J, Schumann L, Pomares FB, Frodl T, Tozzi L, Nemoda Z, Yu P, Szyf M, Khalid-Khan S, Booij L

Abstract

BACKGROUND: Studies in adult depressed patients have indicated that altered DNA methylation patterns at genes related to serotonin and HPA axis functioning (e.g., SLC6A4, FKBP5) are associated with changes in frontolimbic functional connectivity and structure. Here, we examined whether these associations can be generalized to adolescents.

METHODS: 25 adolescents with depression (Mean age = 15.72 ± 0.94 SD; 20 girls) and 20 healthy controls (Mean age = 16.05 ± 1.5 SD; 16 girls) underwent a functional and structural magnetic resonance imaging protocol, which included a resting-state assessment and measures of brain morphometry. DNA was obtained from saliva. Levels of SLC6A4 and FKBP5 methylation were determined using pyrosequencing.

RESULTS: SLC6A4 methylation was linked to amygdala-frontal operculum resting-state functional connectivity (rs-FC), regardless of diagnosis, and was differentially associated with inferior orbitofrontal gyrus (IFOG) gray matter (GM) volume in adolescents with depression and controls. Replicating and extending previous findings in adults, FKBP5 methylation was associated with IFOG GM volume in depressed and healthy adolescents, as well as orbitofrontal cortex (OFC)-rostral prefrontal cortex (RPFC) connectivity in healthy adolescents only.

LIMITATIONS: Effects of medication use or genotype cannot be ruled out. Further, the relatively small sample size and predominately female sample may limit generalizability.

CONCLUSIONS: These findings suggest that previously observed associations between SLC6A4 and FKBP5 methylation and frontolimbic processes in adult depressed patients can be in part generalized to adolescent patients. Further, findings suggest that measuring peripheral methylation at these genes deserves further attention as potential markers of typical and atypical development.

PMID: 32479312 [PubMed - as supplied by publisher]





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