Keyword search (4,164 papers available)

"subjective cognitive decline" Keyword-tagged Publications:

Title Authors PubMed ID
1 The predictive role of olfactory identification on episodic memory and mild cognitive impairment: Results from the CIMA-Q cohort Jobin B; Phillips NA; Frasnelli J; Boller B; 40944318
PSYCHOLOGY
2 A network approach to subjective cognitive decline: Exploring multivariate relationships in neuropsychological test performance across Alzheimer's disease risk states Grunden N; Phillips NA; ; 38458017
PSYCHOLOGY
3 Olfactory function reflects episodic memory performance and atrophy in the medial temporal lobe in individuals at risk for Alzheimer's disease Papadatos Z; Phillips NA; 37146503
PSYCHOLOGY
4 Hearing loss is associated with gray matter differences in older adults at risk for and with Alzheimer's disease Giroud N; Pichora-Fuller MK; Mick P; Wittich W; Al-Yawer F; Rehan S; Orange JB; Phillips NA; 36911511
CRDH
5 Feasibility and preliminary efficacy of the LEAD trial: a cluster randomized controlled lifestyle intervention to improve hippocampal volume in older adults at-risk for dementia N D Koblinsky 35139918
PERFORM
6 Visual Performance and Cortical Atrophy in Vision-Related Brain Regions Differ Between Older Adults with (or at Risk for) Alzheimer's Disease Sana Rehan 34397410
CRDH
7 Neural correlates of resilience to the effects of hippocampal atrophy on memory. Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group 33360019
HKAP

 

Title:Neural correlates of resilience to the effects of hippocampal atrophy on memory.
Authors:Belleville S,  Mellah S,  Cloutier S,  Dang-Vu TT,  Duchesne S,  Maltezos S,  Phillips N,  Hudon C,  CIMA-Q group
Link:https://www.ncbi.nlm.nih.gov/pubmed/33360019
DOI:10.1016/j.nicl.2020.102526
Publication:NeuroImage. Clinical
Keywords:Aging;  Associative memory;  Cognitive reserve;  Hippocampal atrophy;  Mild cognitive impairment;  Subjective cognitive decline; 
PMID:33360019 Category:Neuroimage Clin Date Added:2020-12-29
Dept Affiliation: HKAP
1 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Psychology, Université de Montréal, Pavillon Marie-Victorin, 90 Vincent d'Indy, Montreal, QC H2V 2S9, Canada. Electronic address: sylvie.bellevillle@umontreal.ca.
2 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada. Electronic address: samira.mellah@criugm.qc.ca.
3 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Psychology, Université de Montréal, Pavillon Marie-Victorin, 90 Vincent d'Indy, Montreal, QC H2V 2S9, Canada.
4 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Health, Kinesiology and Applied Physiology, Concordia University, 7141 Sherbrooke Street West, Montreal, QC H4B 1R6, Canada. Electronic address: TT.DangVu@concordia.ca.
5 Department of Radiology, Université Laval, and CERVO Brain Research Center, Institut Universitaire en santé mentale de Québec, 2601 Chemin de la Canardière, Quebec City, QC G1J 2G3, Canada. Electronic address: simon.duchesne@fmed.ulaval.ca.
6 Research Center, Institut Universitaire de Gériatrie de Montréal. 4565 Queen Mary Rd, Montreal, QC H3W 1W5, Canada; Department of Psychology, Université de Montréal, Pavillon Marie-Victorin, 90 Vincent d'Indy, Montreal, QC H2V 2S9, Canada. Electronic address: sarantia.samantha.maltezos@mail.mcgill.ca.
7 Department of Psychology, Concordia University, 1455 Maisonneuve Boulevard West, Montreal, QC H3G 1M8, Canada. Electronic address: natalie.phillips@concordia.ca.
8 Department of Radiology, Université Laval, and CERVO Brain Research Center, Institut Universitaire en santé mentale de Québec, 2601 Chemin de la Canardière, Quebec City, QC G1J 2G3, Canada. Electronic address: carol.hudon@psy.ulaval.ca.

Description:

Neural correlates of resilience to the effects of hippocampal atrophy on memory.

Neuroimage Clin. 2020 Dec 07; 29:102526

Authors: Belleville S, Mellah S, Cloutier S, Dang-Vu TT, Duchesne S, Maltezos S, Phillips N, Hudon C, CIMA-Q group

Abstract

INTRODUCTION: Cognitive reserve can be defined as a property of the brain that enables an individual to sustain cognitive performance in spite of age-related neural changes. This study uses brain imaging to identify which cognitive reserve mechanisms protect against the detrimental effect of hippocampal atrophy on associative memory.

METHODS: The study included 108 older adults from the Quebec Consortium for the early identification of Alzheimer's disease. They received a magnetic resonance imaging examination to measure memory-related activations and hippocampal volume. Participants also completed a reserve-proxy questionnaire, and received a comprehensive clinical assessment.

RESULTS: Higher scores on the reserve questionnaire were associated with more activation in the right inferior temporal and left occipital fusiform gyri. The activation of the right temporal gyrus moderated the relationship between the volume of the hippocampus and face-name memory. A smaller volume was associated with weaker memory in participants with lower activation, but not in those with greater activation.

DISCUSSION: Recruitment of the temporal lobe protects against the detrimental effect of hippocampal atrophy on associative memory and contributes to cognitive reserve.

PMID: 33360019 [PubMed - as supplied by publisher]




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