Keyword search (4,163 papers available)

"technology" Keyword-tagged Publications:

Title Authors PubMed ID
1 Smart Optogenetics for Real-Time Automated Control of Cardiac Electrical Activity Deng S; Harlaar N; Zhang J; Dekker SO; Kudryashova NN; Zhou H; Bart CI; Jin T; Derevyanko G; van Driel W; Panfilov AV; Poelma RH; de Vries AAF; Zhang G; De Coster T; Pijnappels DA; 41684280
CHEMBIOCHEM
2 Mechanistic insights of plant-microbe interactions for enhancing the growth and productivity of plants under salt stress conditions for agricultural sustainability Sharma B; Negi R; Jyothi SR; Gupta A; Jhamta S; Yadav N; Kaur N; Puri P; Thakur SS; Bagavathiappan S; Thakur N; Shreaz S; Madouh TA; Yadav AN; 41245209
BIOLOGY
3 Auditory and vibrotactile interactions in perception of timbre acoustic features Chauvette L; Sophie Grenier A; Albouy P; Coffey E; Zatorre R; Sharp A; 41168236
PSYCHOLOGY
4 Leveraging Personal Technologies in the Treatment of Schizophrenia Spectrum Disorders: Scoping Review D' Arcey J; Torous J; Asuncion TR; Tackaberry-Giddens L; Zahid A; Ishak M; Foussias G; Kidd S; 39348196
PSYCHOLOGY
5 Advancements in Hybrid Cellulose-Based Films: Innovations and Applications in 2D Nano-Delivery Systems Ramezani G; Stiharu I; van de Ven TGM; Nerguizian V; 38667550
ENCS
6 Perinatal, obstetric and parental risk factors for asthma in the offspring throughout childhood: a longitudinal cohort study Caparros-Gonzalez RA; Essau C; Gouin JP; Pemau A; Galvez-Merlin A; de la Torre-Luque A; 37326102
PSYCHOLOGY
7 Online physical exercise intervention in older adults during lockdown: Can we improve the recipe? Granet J; Peyrusqué E; Ruiz F; Buckinx F; Abdelkader LB; Dang-Vu TT; Sirois MJ; Gouin JP; Pageaux B; Aubertin-Leheudre M; 36635450
PERFORM
8 The use of technology in the treatment of youth with eating disorders: A scoping review Dufour R; Novack K; Picard L; Chadi N; Booij L; 36434657
PSYCHOLOGY
9 Coding Public Health Interventions for Health Technology Assessments: A Pilot Experience With WHO's International Classification of Health Interventions (ICHI) Wübbeler M; Geis S; Stojanovic J; Elliott L; Gutierrez-Ibarluzea I; Lenoir-Wijnkoop I; 34222165
HKAP
10 Recent Advances of DNA Tetrahedra for Therapeutic Delivery and Biosensing. Copp W, Pontarelli A, Wilds CJ 33506614
CHEMBIOCHEM
11 Digital Game Interventions for Youth Mental Health Services (Gaming My Way to Recovery): Protocol for a Scoping Review. Ferrari M, McIlwaine SV, Reynolds JA, Archie S, Boydell K, Lal S, Shah JL, Henderson J, Alvarez-Jimenez M, Andersson N, Boruff J, Nielsen RKL, Iyer SN 32579117
CONCORDIA
12 O6-Alkylguanine DNA Alkyltransferase Mediated Disassembly of a DNA Tetrahedron. Copp W, Wilds CJ 32543755
CHEMBIOCHEM
13 Evaluating Public Health Interventions: A Neglected Area in Health Technology Assessment. Stojanovic J, Wübbeler M, Geis S, Reviriego E, Gutiérrez-Ibarluzea I, Lenoir-Wijnkoop I 32391300
HKAP
14 Augmented reality mastectomy surgical planning prototype using the HoloLens template for healthcare technology letters. Amini S, Kersten-Oertel M 32038868
PERFORM
15 Exploring the use of smartphones and tablets among people with visual impairments: Are mainstream devices replacing the use of traditional visual aids? Martiniello N, Eisenbarth W, Lehane C, Johnson A, Wittich W 31697612
PSYCHOLOGY
16 Start-up of oxygen-limited autotrophic partial nitrification-anammox process for treatment of nitrite-free wastewater in a single-stage hybrid bioreactor. Hosseinpour B, Saborimanesh N, Yerushalmi L, Walsh D, Mulligan CN 31378146
CSFG

 

Title:O6-Alkylguanine DNA Alkyltransferase Mediated Disassembly of a DNA Tetrahedron.
Authors:Copp W,  Wilds CJ
Link:https://www.ncbi.nlm.nih.gov/pubmed/32543755?dopt=Abstract
DOI:10.1002/chem.202002565
Publication:Chemistry (Weinheim an der Bergstrasse, Germany)
Keywords:DNA nanotechnology;  DNA tetrahedron;  DNA-protein interactions;  hAGT;  self-assembly; 
PMID:32543755 Category:Chemistry Date Added:2020-06-17
Dept Affiliation: CHEMBIOCHEM
1 Department of Chemistry and Biochemistry, Concordia University, Montréal, Québec, H4B 1R6, Canada.

Description:

O6-Alkylguanine DNA Alkyltransferase Mediated Disassembly of a DNA Tetrahedron.

Chemistry. 2020 Jun 16;:

Authors: Copp W, Wilds CJ

Abstract

Tetrahedron DNA structures were formed by the assembly of three-way junction (TWJ) oligonucleotides containing O6-2'-deoxyguanosine-alkylene-O6-2'-deoxyguanosine (butylene and heptylene linked) intrastrand cross-links (IaCLs) lacking a phosphodiester group between the 2'-deoxyribose residues. The DNA tetrahedra containing TWJs were shown to undergo an unhooking reaction by the human DNA repair protein O6-alkylguanine DNA alkyltransferase (hAGT) resulting in structure disassembly. The unhooking reaction of hAGT towards the DNA tetrahedra was observed to be moderate to virtually complete depending on the protein equivalents. DNA tetrahedron structures have been explored as drug delivery platforms that release their payload in response to triggers such as light, chemical agents or hybridization of release strands. The dismantling of DNA tetrahedron structures by a DNA repair protein contributes to the armamentarium of approaches for drug release employing DNA nanostructures.

PMID: 32543755 [PubMed - as supplied by publisher]




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