Author(s): Nasr MA; Martin VJJ; Kwan DH;

Reprogramming cellular behaviour is one of the hallmarks of synthetic biology. To this end, prokaryotic allosteric transcription factors (aTF) have been repurposed as versatile tools for processing small molecule signals into cellular responses. Expanding the toolbox of aTFs that recognize new inducer molecules is of considerable interest in many applicat ...

Article GUID: 37377432

Author(s): Primavesi R; Patocka C; Burcheri A; Coutin A; Elhalwi AM; Ali A; Pandya A; Gagné A; Johnston B; Thoma B; LeBlanc C; Fovet F; Gallinger J; Mohadeb J; Ragheb M; Dong S; Smith S; Oyedokun T; Newmarch T; Knight V; McColl T;

Objectives: This call to action seeks to improve emergency care in Canada for equity-deserving communities, enabled by equitable representation among emergency physicians nationally. Specifically, this work describes current resident selection processes and makes recommendations to enhance the eq ...

Article GUID: 37368231

Author(s): Lawrence ER; Pedersen EJ; Fraser DJ;

The broad scale distribution of population-specific genetic diversity (GDP ) across taxa remains understudied relative to species diversity gradients, despite its relevance for systematic conservation planning. We used nuclear DNA data collected from 3678 vertebrate populations across the Americas to assess the role of environmental and spatial variables ...

Article GUID: 37365672

Author(s): Isola C; Granger S; Turner N; LeBlanc MM; Barling J;

This study investigates the link between intimate partner violence (IPV) and work withdrawal (including absence frequency, partial absenteeism, and turnover intentions) in the context of partners' interference with victims at work and family supportive supervision of victims at work. Using the work-home resources model, we propose that (1) partner int ...

Article GUID: 37359457

Author(s): Peters JA; Farhadloo M;

Introduction: To assess the effects of various non-pharmaceutical interventions (NPI) on cases, hospitalizations, and mortality during the first wave of the COVID-19 pandemic. Methods: To empirically investigate the impacts of different NPIs on COVID-19-related health outcomes, a systematic literature review was conducted. We studied the effects of 10 NP ...

Article GUID: 37362389

Author(s): Sultana S; Abdullah M; Li J; Hochstrasser M; Kachroo AH;

Yeast and humans share thousands of genes despite a billion years of evolutionary divergence. While many human genes can functionally replace their yeast counterparts, nearly half of the tested shared genes cannot. For example, most yeast proteasome subunits are "humanizable", except subunits comprising the ß-ring core, including ß2c (HsPSMB7, a constitut ...

Article GUID: 37364278

Author(s): Ghani HU; Ryberg M; Bjørn A; Hauschild MZ; Gheewala SH;

Purpose: Extensive agriculture activities for crop production have led to increasing environmental impacts that threaten to exceed environmentally safe limits. The purpose of this study is to analyze resource efficiency of the agri-food industry, considering the case of sugarcane production in Pakistan. Methods: A holistic approach has been applied by de ...

Article GUID: 37363084

Author(s): Roozbeh Nia A; Awasthi A; Bhuiyan N;

Within an uncertain environment and following carbon trade policies, this study uses the Extended Exergy Accounting (EEA) method for coal supply chains (SCs) in eight of the world's most significant coal consuming countries. The purpose is to improve the sustainability of coal SCs in terms of Joules rather than money while considering economic, enviro ...

Article GUID: 37363701

Author(s): Audet JS; Jacmin-Park S; Kheloui S; Gravel C; Juster RP; Aardema F;

Specific concerns have been raised for those suffering from obsessive-compulsive disorder (OCD) during the COVID-19 pandemic, particularly those suffering from contamination fear. Investigation in non-clinical and OCD samples have reported an increase in contamination symptoms in association with the severity of the COVID-19 pandemic. In particular, stres ...

Article GUID: 37359678

Author(s): Krause S; Radomsky AS;

Purpose: Cognitive models of mental contamination (feelings of dirtiness/washing behaviour that arise without direct contact with a contaminant) highlight the central role of perceptions of violation in the onset and maintenance of these feelings. Little research has been done to clarify violation-specific appraisals relevant to mental contamination. Perc ...

Article GUID: 37363745

Author(s): Jason W Payne

Research on memory reconsolidation has relied heavily on the use of Pavlovian auditory cued-fear conditioning. Here, an auditory cue (CS) is paired with a footshock (US) and the CS is later able to evoke a freezing response when presented alone. Some treatments, when administered to conditioned subjects immediately following a CS-alone (memory reactivatio ...

Article GUID: 37347748

Author(s): Sares AG; Gilbert AC; Zhang Y; Iordanov M; Lehmann A; Deroche MLD;

Auditory memory is an important everyday skill evaluated more and more frequently in clinical settings as there is recently a greater recognition of the cost of hearing loss to cognitive systems. Testing often involves reading a list of unrelated items aloud; but prosodic variations in pitch and timing across the list can affect the number of items rememb ...

Article GUID: 37338981