Author(s): Jourde HR; Merlo R; Brooks M; Rowe M; Coffey EBJ;

Closed-loop auditory stimulation (CLAS) is a brain modulation technique in which sounds are timed to enhance or disrupt endogenous neurophysiological events. CLAS of slow oscillation up-states in sleep is becoming a popular tool to study and enhance sleep's functions, as it increases slow oscillations, evokes sleep spindles and enhances memory conso ...

Article GUID: 37675803

Author(s): Pontarelli A; Wilds CJ;

The clinical success of the antisense approach for the treatment of genetic disorders is indisputably the result of chemical modifications along the oligonucleotide (ON) scaffold, which impart desirable properties including high RNA affinity, nuclease stability and improved drug delivery. While effective, many modifications are not capable of eliciting ...

Article GUID: 37667655

Author(s): Bethell J; Andrew MK; Hothi S; Mick P; Morgan D; O' Connell ME; Phillips NA; Stewart S; Walker JD; Wittich W; McGilton KS;

Objectives: This study tested the association between neuroticism and six cognitive measures, and examined the potential mediating roles of social connection (social isolation and loneliness) among middle-aged and older adults. Methods: This cross-sectional study was a secondary analysis of th ...

Article GUID: 37667914

Author(s): Momeni Z; Bagchi A;

Earthquakes can cause significant damage to constructed structures, leading engineers to design systems that effectively reduce damage and improve real-time vibration control. While base isolation is a commonly used passive method for seismic protection in highway structures, it has limitations such as a lack of immediate adaptation, constrained power d ...

Article GUID: 37662735

Author(s): Xiao Y; Gilmore G; Kai J; Lau JC; Peters T; Khan AR;

Population-averaged brain atlases, that are represented in a standard space with anatomical labels, are instrumental tools in neurosurgical planning and the study of neurodegenerative conditions. Traditional brain atlases are primarily derived from anatomical scans and contain limited information regarding the axonal organization of the white matter. Wi ...

Article GUID: 37663773

Author(s): Malmir T; Héroux M; Lagos D; Eicker U;

Landfills are extensively applied to dispose of municipal solid wastes in developed and developing countries. Landfill gas generation from biodegradable organic wastes can be collected and converted to energy. When the gas collection system is shutdown, some of this gas can accumulate and be stored inside the landfill. Using the gas storage capacity of ...

Article GUID: 37659122

Author(s): Singh V; Raheja Y; Basotra N; Sharma G; Tsang A; Chadha BS;

Background: The filamentous fungus Rasamsonia emersonii has immense potential to produce biorefinery relevant thermostable cellulase and hemicellulase enzymes using lignocellulosic biomass. Previously in our lab, a hyper-cellulase producing strain of R. emersonii was developed through classical breeding and system biology approaches. ACE1, a pivotal tra ...

Article GUID: 37658430

Author(s): Pyne ME; Bagley JA; Narcross L; Kevvai K; Exley K; Davies M; Wang Q; Whiteway M; Martin VJJ;

Saccharomyces cerevisiae is a workhorse of industrial biotechnology owing to the organism's prominence in alcohol fermentation and the suite of sophisticated genetic tools available to manipulate its metabolism. However, S. cerevisiae is not suited to overproduce many bulk bioproducts, as t ...

Article GUID: 37652930

Author(s): Manera V; Partos C; Beauchet O; Benoit M; Dupetit B; Elbaum J; Fabre R; Gindt M; Gros A; Guerchouche R; Klöppel S; König A; Martin A; Mouton A; Pancrazi MP; Politis A; Robert G; Sacco G; Sacconi S; Sawchuk K; Solari F; Thiebot L; Trima ...

Introduction: The use of teleconsultations for mental health has drastically increased since 2020 due to the Covid19 pandemic. In the present paper, we aimed to analyze the advantages and disadvantages of teleconsultations for mental health compared to face-to-face consultations, and to provide ...

Article GUID: 37655117

Author(s): Vasiliadis HM; Spagnolo J; Fleury MJ; Gouin JP; Roberge P; Bartram M; Grenier S; Shen-Tu G; Vena JE; Wang J;

Background: Scarce are the studies focusing on initiation of new mental health service use (MHSU) and distinguishing individuals who have sought services but have been unsuccessful in accessing these. Aims: Assessing the factors associated with initiating new MHSU as compared to no MHSU due to ...

Article GUID: 37646244

Author(s): Giannis I; Wrosch C; Herriot H; Gouin JP;

ackground: Older adults often experience an increase in low-grade chronic inflammation. Purpose in life could act as a protective factor as it is associated with beneficial health outcomes. Purpose in life may exert part of its adaptive function by promoting persistence in goal pursuit. During older adulthood, however, when many individuals experience a ...

Article GUID: 37643057

Author(s): Emborg M; Lloyd S; Olsen S;

No abstract available

Article GUID: 37641449