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The Dyadic Health Influence Model

Author(s): Huelsnitz CO; Jones RE; Simpson JA; Joyal-Desmarais K; Standen EC; Auster-Gussman LA; Rothman AJ;

Relationship partners affect one another's health outcomes through their health behaviors, yet how this occurs is not well understood. To fill this gap, we present the Dyadic Health Influence Model (DHIM). The DHIM identifies three routes through which a person (the agent) can impact the he ...

Article GUID: 34873983


Pre- and post-industrial levels of polycyclic aromatic hydrocarbons in sediments from the Estuary and Gulf of St. Lawrence (eastern Canada)

Author(s): Corminboeuf A; Montero-Serrano JC; St-Louis R; Dalpé A; Gélinas Y;

The concentrations of 23 polycyclic aromatic hydrocarbons (PAHs; 16 parent PAHs and 7 alkyl-PAHs) were determined in 45 surface sediment and 7 basal sediment box core samples retrieved from the Estuary and Gulf of St. Lawrence in eastern Canada. The concentration sums of 16 priority PAHs (S<sub>16</sub>PAHs) in the surface sediments (represe ...

Article GUID: 34871900


Associations of the BDNF Val66Met Polymorphism With Body Composition, Cardiometabolic Risk Factors, and Energy Intake in Youth With Obesity: Findings From the HEARTY Study

Author(s): Goldfield GS; Walsh J; Sigal RJ; Kenny GP; Hadjiyannakis S; De Lisio M; Ngu M; Prud' homme D; Alberga AS; Doucette S; Goldfield DB; Cameron JD;

The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is functionally related to BDNF, and is associated with obesity and metabolic complications in adults, but limited research exists among adolescents. This study comparatively examined carriers and non-carriers of the BDNF Val66M ...

Article GUID: 34867148


The trade-off between pulse duration and power in optical excitation of midbrain dopamine neurons approximates Bloch's law

Author(s): Pallikaras V; Carter F; Velazquez-Martinez DN; Arvanitogiannis A; Shizgal P;

Optogenetic experiments reveal functional roles of specific neurons. However, functional inferences have been limited by widespread adoption of a restricted set of stimulation parameters. Broader exploration of the parameter space can deepen insight into the mapping between selective neural activity and behavior. In this way, characteristics of the acti ...

Article GUID: 34864162


A comparison of the effect of physical activity and cognitive training on dual-task performance in older adults

Author(s): Vrinceanu T; Blanchette CA; Intzandt B; Lussier M; Pothier K; Vu TTM; Nigam A; Bosquet L; Karelis AD; Li KZH; Berryman N; Bherer L;

Objectives: Studies suggest that cognitive training and physical activity can improve age-related deficits in dual-task performances. However, both of these interventions have never been compared in the same study. This paper investigates the improvement in dual-task performance in two types of ...

Article GUID: 34865009


White matter correlates of sensorimotor synchronization in persistent developmental stuttering

Author(s): Jossinger S; Sares A; Zislis A; Sury D; Gracco V; Ben-Shachar M;

Introduction: Individuals with persistent developmental stuttering display deficits in aligning motor actions to external cues (i.e., sensorimotor synchronization). Diffusion imaging studies point to stuttering-associated differences in dorsal, not ventral, white matter pathways, and in the cerebellar peduncles. Here, we studied microstructural white ma ...

Article GUID: 34856426


Insights from a dyslexia simulation font: Can we simulate reading struggles of individuals with dyslexia?

Author(s): Stark Z; Franzen L; Johnson AP;

No abstract

Article GUID: 34854169


Caloric restriction causes a distinct reorganization of the lipidome in quiescent and non-quiescent cells of budding yeast

Author(s): Mohammad K; Orfanos E; Titorenko VI;

After budding yeast cells cultured in a nutrient-rich liquid medium with 0.2% glucose (under caloric restriction conditions) or 2% glucose (under non-caloric restriction conditions), ferment glucose to ethanol and then consume ethanol, they enter the stationary phase. The process of their chronological aging begins. At that point, the yeast culture star ...

Article GUID: 34853658


The Role of Context Conditioning in the Reinstatement of Responding to an Alcohol-Predictive Conditioned Stimulus

Author(s): LeCocq MR; Sun S; Chaudhri N;

Re-exposure to an unconditioned stimulus (US) can reinstate extinguished conditioned responding elicited by a conditioned stimulus (CS). We tested the hypothesis that the reinstatement of responding to an appetitive CS is driven by an excitatory association formed between the US and the context that the US was ingested in during US re-exposure. Male, Lo ...

Article GUID: 34852244


Discovery of new vascular disrupting agents based on evolutionarily conserved drug action, pesticide resistance mutations, and humanized yeast

Author(s): Garge RK; Cha HJ; Lee C; Gollihar JD; Kachroo AH; Wallingford JB; Marcotte EM;

Thiabendazole (TBZ) is an FDA-approved benzimidazole widely used for its antifungal and antihelminthic properties. We showed previously that TBZ is also a potent vascular disrupting agent and inhibits angiogenesis at the tissue level by dissociating vascular endothelial cells in newly formed blood vessels. Here, we uncover TBZ's molecular target and ...

Article GUID: 34849907


The zinc cluster transcription factor Rha1 is a positive filamentation regulator in Candida albicans

Author(s): Omran RP; Ramírez-Zavala B; Aji Tebung W; Yao S; Feng J; Law C; Dumeaux V; Morschhäuser J; Whiteway M;

Zinc cluster transcription factors are essential fungal regulators of gene expression. In the pathogen Candida albicans, the gene orf19.1604 encodes a zinc cluster transcription factor regulating filament development. Hyperactivation of orf19.1604, which we have named RHA1 for Regulator of Hyph ...

Article GUID: 34849863


Factors Associated with Speech-Recognition Performance in School-Aged Children with Cochlear Implants and Early Auditory-Verbal Intervention

Author(s): Wolfe J; Deroche M; Neumann S; Hanna L; Towler W; Wilson C; Bien AG; Miller S; Schafer EC; Gracco V;

<strong>Background:</strong> Considerable variability exists in the speech recognition abilities achieved by children with cochlear implants (CIs) due to varying demographic and performance variables including language abilities.

<strong>Purpose:</strong> This ...

Article GUID: 34847584


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