Keyword search (3,448 papers available)


Surface Response Based Modeling of Liposome Characteristics in a Periodic Disturbance Mixer.

Author(s): López RR, Ocampo I, Sánchez LM, Alazzam A, Bergeron KF, Camacho-León S, Mounier C, Stiharu I, Nerguizian V

Micromachines (Basel). 2020 Feb 25;11(3): Authors: López RR, Ocampo I, Sánchez LM, Alazzam A, Bergeron KF, Camacho-León S, Mounier C, Stiharu I, Nerguizian V

Article GUID: 32106424
Dielectrophoresis Multipath Focusing of Microparticles through Perforated Electrodes in Microfluidic Channels.

Author(s): Alazzam A, Al-Khaleel M, Riahi MK, Mathew B, Gawanmeh A, Nerguizian V

Biosensors (Basel). 2019 Aug 07;9(3): Authors: Alazzam A, Al-Khaleel M, Riahi MK, Mathew B, Gawanmeh A, Nerguizian V

Article GUID: 31394810
Fabrication of Porous Gold Film Using Graphene Oxide as a Sacrificial Layer.

Author(s): Alazzam A, Alamoodi N, Abutayeh M, Stiharu I, Nerguizian V

Materials (Basel). 2019 Jul 18;12(14): Authors: Alazzam A, Alamoodi N, Abutayeh M, Stiharu I, Nerguizian V

Article GUID: 31323903
Lateral fluid flow fractionation using dielectrophoresis (LFFF-DEP) for size-independent, label-free isolation of circulating tumor cells.

Author(s): Waheed W, Alazzam A, Mathew B, Christoforou N, Abu-Nada E

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jun 15;1087-1088:133-137 Authors: Waheed W, Alazzam A, Mathew B, Christoforou N, Abu-Nada E

Article GUID: 29734073
The effect of dielectrophoresis on living cells: crossover frequencies and deregulation in gene expression.

Author(s): Nerguizian V, Stiharu I, Al-Azzam N, Yassine-Diab B, Alazzam A

Analyst. 2019 May 17;: Authors: Nerguizian V, Stiharu I, Al-Azzam N, Yassine-Diab B, Alazzam A

Article GUID: 31099354
Title:Lateral fluid flow fractionation using dielectrophoresis (LFFF-DEP) for size-independent, label-free isolation of circulating tumor cells.
Authors:Waheed W,  Alazzam A,  Mathew B,  Christoforou N,  Abu-Nada E
Link:https://www.ncbi.nlm.nih.gov/pubmed/29734073?dopt=Abstract
Category:J Chromatogr B Analyt Technol Biomed Life Sci
PMID:29734073
Dept Affiliation: ENCS
1 Mechanical Engineering Department, Khalifa University, Abu Dhabi, P.O. Box 127788, United Arab Emirates.
2 Mechanical Engineering Department, Khalifa University, Abu Dhabi, P.O. Box 127788, United Arab Emirates; Concave Research center, Concordia University, Montreal H3G 1M8, Canada; Electrical Engineering Department, École de Technologie Supérieure, Montréal H3C 1K3, Canada. Electronic address: anas.alazzam@ku.ac.ae.
3 Mechanical Engineering Department, UAEU, Al Ain, P.O. Box 15551, United Arab Emirates.
4 Humacyte Inc., 7020 Kit Creek Rd, Morrisville, NC 27560, USA.

Description:

Lateral fluid flow fractionation using dielectrophoresis (LFFF-DEP) for size-independent, label-free isolation of circulating tumor cells.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jun 15;1087-1088:133-137

Authors: Waheed W, Alazzam A, Mathew B, Christoforou N, Abu-Nada E

Abstract

This short communication introduces a continuous-flow, dielectrophoresis-based lateral fluid flow fractionation microdevice for detection/isolation of circulating tumor cells in the presence of other haematological cells. The device utilizes two sets of planar interdigitated transducer electrodes micropatterned on top of a glass wafer using standard microfabrication techniques. A microchannel with a single inlet and two outlets, realized in polydimethylsiloxane, is bonded on the glass substrate. The two sets of electrodes slightly protrude into the microchannel. Both of the electrode sets are energized with signals at different frequencies and different operating voltages ensuring that the cancer cells experience positive dielectrophoretic force from one set of the electrodes and negative dielectrophoretic force from the other array. Normal cells experience unequal negative dielectrophoretic forces from opposing sets of electrodes. The resultant dielectrophoretic forces on cancer and normal cells push them to flow towards their designed outlets. Successful isolation of green fluorescent protein-labelled MDA-MB-231 breast cancer cells from regular blood cells, both suspended in a sucrose/dextrose medium, is reported in this work.

PMID: 29734073 [PubMed - indexed for MEDLINE]