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Comment on the article "Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome 486 (2020) 110102"

Author(s): Arsalan Rahimabadi

Considering the reaction schemes (20) and (21) in Fornari et al., 2020, the fragmentation terms Fi (Eq. (22) in Fornari et al., 2020) are not correct. Thus, the fragmentation terms Fi (Eq. (12) in Fornari et al., 2020) are also incorrect when the reaction s...

Article GUID: 34843739


Title:Comment on the article "Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome 486 (2020) 110102"
Authors:Arsalan Rahimabadi
Link:https://pubmed.ncbi.nlm.nih.gov/34843739/
DOI:10.1016/j.jtbi.2021.110965
Category:
PMID:34843739
Dept Affiliation: PERFORM
1 PERFORM Centre, Concordia University, Montreal, QC, Canada; ECE Department, Concordia University, Montreal, QC, Canada.

Description:

Considering the reaction schemes (20) and (21) in Fornari et al., 2020, the fragmentation terms Fi (Eq. (22) in Fornari et al., 2020) are not correct. Thus, the fragmentation terms Fi (Eq. (12) in Fornari et al., 2020) are also incorrect when the reaction schemes (10) and (11) in Fornari et al., 2020 are taken into account. Here, the correct equations will be presented.