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Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.

Author(s): Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Bipolar Disord. 2020 Mar 30;: Authors: Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Article GUID: 32232937
Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer's disease.

Author(s): Hadoux X, Hui F, Lim JKH, Masters CL, Pébay A, Chevalier S, Ha J, Loi S, Fowler CJ, Rowe C, Villemagne VL, Taylor EN, Fluke C, Soucy JP, Les...

Nat Commun. 2019 Sep 17;10(1):4227 Authors: Hadoux X, Hui F, Lim JKH, Masters CL, Pébay A, Chevalier S, Ha J, Loi S, Fowler CJ, Rowe C, Villemagne VL, Taylor EN, Fluke C, Soucy JP, Lesage F, ...

Article GUID: 31530809
Title:Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.
Authors:Lavin-Gonzalez P,  Bourguignon C,  Crescenzi O,  Beaulieu S,  Storch KF,  Linnaranta O
Link:https://www.ncbi.nlm.nih.gov/pubmed/32232937?dopt=Abstract
DOI:10.1111/bdi.12903
Category:Bipolar Disord
PMID:32232937
Dept Affiliation: PSYCHOLOGY
1 Department of Psychiatry, McGill University, Montreal, Québec, Canada.
2 Douglas Group for Sleep and Biological Rhythms, Douglas Mental Health University Institute, Montreal, Québec, Canada.
3 Integrated Program in Neuroscience, McGill University, Montreal, Québec, Canada.
4 Department of Psychology, Concordia University, Montreal, Québec, Canada.

Description:

Inactograms and objective sleep measures as means to capture subjective sleep problems in patients with a bipolar disorder.

Bipolar Disord. 2020 Mar 30;:

Authors: Lavin-Gonzalez P, Bourguignon C, Crescenzi O, Beaulieu S, Storch KF, Linnaranta O

Abstract

BACKGROUND: Sleep problems are common in bipolar disorders (BDs). To objectively characterize these problems in BDs, further methodological development is needed to capture subjective insomnia.

AIM: To test psychometric properties of the Athens Insomnia Scale (AIS), and associations with actigraphy-derived measures, applying modifications in actigraphy data processing to capture features of perturbed sleep in patients with a BD.

METHODS: Seventy-four patients completed the AIS and the Quick Inventory of Depressive Symptomatology, self-report (QIDS-SR-16). Locomotor activity was continuously recorded by wrist-actigraphy for =10 consecutive days. We computed the sleep onset/offset, the center of daily inactivity (CenDI), as a proxy for chronotype, and the degree of consolidation of daily inactivity (ConDI), as a proxy for sleep-wake rhythm strength.

RESULTS: AIS showed good psychometric properties (Cronbach's alpha=0.84; test-retest correlation=0.84, p<.001). Subjective sleep problems correlated moderately with a later sleep phase (CenDI with AIS rho=0.34, p=.003), lower consolidation (ConDI with AIS rho=-0.22, p=.05; with QIDS-SR-16 rho=-0.27, p=.019), later timing of sleep offset (with AIS rho=0.49, p= =.001, with QIDS-SR-16 rho=0.36, p=.002), and longer total sleep (with AIS rho=0.29, p=.012, with QIDS-SR-16 rho=0.41, p==.001). While AIS was psychometrically more solid, correlations with objective sleep were more consistent across time for QIDS-SR-16.

CONCLUSIONS: AIS and QIDS-SR-16 are suitable for clinical screening of sleep problems among patients with a BD. Subjective insomnia associated with objective measures. For clinical and research purposes, actigraphy and data visualization on inactograms are useful for accurate longitudinal characterization of sleep patterns.

PMID: 32232937 [PubMed - as supplied by publisher]